Histone demethylase Jmjd3 modulates osteoblast apoptosis induced by tumor necrosis factor-alpha through directly targeting RASSF5

Histone demethylase Jmjd3 regulates osteoblast apoptosis through targeting anti-apoptotic protein Bcl-2 and pro-apoptotic protein Bim

(2016) Di Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

H3K27 Demethylase JMJD3 Employs the NF- B and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis

(2016) W.-Y. Park et al.   CANCER RESEARCH

Fluid shear stress suppresses TNF-α-induced apoptosis in MC3T3-E1 cells: Involvement of ERK5-AKT-FoxO3a-Bim/FasL signaling pathways

(2016) Geng Bin et al.   EXPERIMENTAL CELL RESEARCH

Histone H3K27 Demethylase JMJD3 in Cooperation with NF-κB Regulates Keratinocyte Wound Healing

(2016) Jungtae Na et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Histone Demethylase Jumonji Coordinates Cellular Senescence Including Secretion of Neural Stem Cell–Attracting Cytokines

(2015) Patrick M. Perrigue et al.   MOLECULAR CANCER RESEARCH

Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process

(2014) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Histone Lysine Demethylase JMJD3/KDM6B Is Recruited to p53 Bound Promoters and Enhancer Elements in a p53 Dependent Manner

(2014) Kristine Williams et al.   PLoS One

Retinoic Acid Activates Two Pathways Required for Meiosis in Mice

(2014) Jana Koubova et al.   PLoS Genetics

Classical and Paradoxical Effects of TNF-α on Bone Homeostasis

(2014) Bilal Osta et al.   Frontiers in Immunology

Jmjd3 Inhibits Reprogramming by Upregulating Expression of INK4a/Arf and Targeting PHF20 for Ubiquitination

(2013) Wei Zhao et al.   CELL

Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells

(2013) Y Wei et al.   LEUKEMIA

Expression and significance of histone H3K27 demethylases in renal cell carcinoma

(2012) Yongqing Shen et al.   BMC CANCER

A Comprehensive Survey of Ras Mutations in Cancer

(2012) I. A. Prior et al.   CANCER RESEARCH

Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program

(2012) C. Estaras et al.   DEVELOPMENT

Induction of osteoclastogenesis in an in vitro model of Gaucher disease is mediated by T cells via TNF-α

(2012) Juan M. Mucci et al.   GENE

Histone Demethylase KDM6B Promotes Epithelial-Mesenchymal Transition

(2012) Sivakumar Ramadoss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

(2012) Laurens Kruidenier et al.   NATURE

Molecular mechanisms and potential functions of histone demethylases

(2012) Susanne Marije Kooistra et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone Demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Protein Nuclear Stabilization

(2012) Chibawanye I. Ene et al.   PLoS One

H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic geneBCL2determines ERα ligand dependency

(2011) Amy Svotelis et al.   EMBO JOURNAL

KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells

(2011) Fábio Pereira et al.   HUMAN MOLECULAR GENETICS

The H3K27me3 demethylase, KDM6B, is induced by Epstein–Barr virus and over-expressed in Hodgkin's Lymphoma

(2011) J A Anderton et al.   ONCOGENE

p53 Interaction with JMJD3 Results in Its Nuclear Distribution during Mouse Neural Stem Cell Differentiation

(2011) Susana Solá et al.   PLoS One

Tumor Suppressor Ras Association Domain Family 5 (RASSF5/NORE1) Mediates Death Receptor Ligand-induced Apoptosis

(2010) Jikyoung Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

NORE1A Tumor Suppressor Candidate Modulates p21CIP1 via p53

(2009) D. F. Calvisi et al.   CANCER RESEARCH

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

(2009) Francesca De Santa et al.   EMBO JOURNAL

Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes

(2009) Tanya Shaw et al.   EMBO REPORTS

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

(2009) K. Agger et al.   GENES & DEVELOPMENT

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

(2008) Thomas Kuilman et al.   CELL

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY