Sacubitril/Valsartan Decreases Cardiac Fibrosis in Left Ventricle Pressure Overload by Restoring PKG Signaling in Cardiac Fibroblasts

Resident fibroblast expansion during cardiac growth and remodeling

(2018) Malina J. Ivey et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure

(2018) Ryan M. Burke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LCZ696, an angiotensin receptor-neprilysin inhibitor, improves cardiac function with the attenuation of fibrosis in heart failure with reduced ejection fraction in streptozotocin-induced diabetic mice

(2016) Yasunori Suematsu et al.   EUROPEAN JOURNAL OF HEART FAILURE

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

(2016) Onur Kanisicak et al.   Nature Communications

Pre-treatment with LCZ696, an orally active angiotensin receptor neprilysin inhibitor, prevents ischemic brain damage

(2015) Hui-Yu Bai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Thioredoxin-Interacting Protein Is a Biomechanical Regulator of Src Activity

(2014) Oded N. Spindel et al.   CIRCULATION RESEARCH

Myocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels

(2014) M. A. Trembley et al.   DEVELOPMENT

Efficacy and Safety of LCZ696, a First-in-Class Angiotensin Receptor Neprilysin Inhibitor, in Asian Patients With Hypertension

(2014) Kazuomi Kario et al.   HYPERTENSION

Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis

(2014) Thomas Moore-Morris et al.   JOURNAL OF CLINICAL INVESTIGATION

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

(2014) John J.V. McMurray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Guanylyl cyclase/natriuretic peptide receptor-A signaling antagonizes phosphoinositide hydrolysis, Ca2+ release, and activation of protein kinase C

(2014) Kailash N. Pandey   Frontiers in Molecular Neuroscience

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

The Actin–MRTF–SRF Gene Regulatory Axis and Myofibroblast Differentiation

(2012) Eric M. Small   Journal of Cardiovascular Translational Research

Guanylyl cyclase / atrial natriuretic peptide receptor-A: role in the pathophysiology of cardiovascular regulation

(2011) Kailash N. Pandey   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Heart Disease and Stroke Statistics—2009 Update

(2009) et al.   CIRCULATION

Differential VASP phosphorylation controls remodeling of the actin cytoskeleton

(2009) P. M. Benz et al.   JOURNAL OF CELL SCIENCE

Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi)

(2009) Jessie Gu et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Regulation of natriuretic peptide receptor-A gene expression and stimulation of its guanylate cyclase activity by transcription factor Ets-1

(2008) Prerna Kumar et al.   BIOSCIENCE REPORTS

Cardiac Plasticity

(2008) Joseph A. Hill et al.   NEW ENGLAND JOURNAL OF MEDICINE