Transcription factor TAp73 and microRNA-449 complement each other to support multiciliogenesis

Motile cilia of the male reproductive system require miR-34/miR-449 for development and function to generate luminal turbulence

(2019) Shuiqiao Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multicilin and activated E2f4 induce multiciliated cell differentiation in primary fibroblasts

(2018) Seongjae Kim et al.   Scientific Reports

The Spatiotemporal Expression Pattern of MicroRNA in the Developing Mouse Nervous System

(2018) Pengcheng Shu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Infertility in an adult cohort with primary ciliary dyskinesia: phenotype–gene association

(2017) Gert Jan Vanaken et al.   EUROPEAN RESPIRATORY JOURNAL

The development and functions of multiciliated epithelia

(2017) Nathalie Spassky et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit

(2017) Tobias Otto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis

(2017) Munemasa Mori et al.   Nature Communications

Loss of p73 in ependymal cells during the perinatal period leads to aqueductal stenosis

(2017) Masashi Fujitani et al.   Scientific Reports

E2f4 and E2f5 are essential for the development of the male reproductive system

(2016) Paul S. Danielian et al.   CELL CYCLE

Age-Dependent Niche Signals from the Choroid Plexus Regulate Adult Neural Stem Cells

(2016) Violeta Silva-Vargas et al.   Cell Stem Cell

GEMC1 is a critical regulator of multiciliated cell differentiation

(2016) Berta Terré et al.   EMBO JOURNAL

MicroRNA‐34/449 controls mitotic spindle orientation during mammalian cortex development

(2016) Juan Pablo Fededa et al.   EMBO JOURNAL

GemC1 controls multiciliogenesis in the airway epithelium

(2016) Marina Arbi et al.   EMBO REPORTS

TAp73 is a central transcriptional regulator of airway multiciliogenesis

(2016) Alice Nemajerova et al.   GENES & DEVELOPMENT

Systematic Analysis ofCCNOVariants in a Defined Population: Implications for Clinical Phenotype and Differential Diagnosis

(2016) Israel Amirav et al.   HUMAN MUTATION

Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells

(2016) Li Li et al.   NATURE CELL BIOLOGY

Cilia-based flow network in the brain ventricles

(2016) R. Faubel et al.   SCIENCE

p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network

(2016) Clayton B. Marshall et al.   Cell Reports

Oasis: online analysis of small RNA deep sequencing data

(2015) Vincenzo Capece et al.   BIOINFORMATICS

Gmnc Is a Master Regulator of the Multiciliated Cell Differentiation Program

(2015) Feng Zhou et al.   CURRENT BIOLOGY

Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche

(2015) C. Kyrousi et al.   DEVELOPMENT

p73 is required for ependymal cell maturation and neurogenic SVZ cytoarchitecture

(2015) L. Gonzalez-Cano et al.   Developmental Neurobiology

Ciliary function and motor protein composition of human fallopian tubes

(2015) Johanna Raidt et al.   HUMAN REPRODUCTION

Spatially Heterogeneous Choroid Plexus Transcriptomes Encode Positional Identity and Contribute to Regional CSF Production

(2015) M. P. Lun et al.   JOURNAL OF NEUROSCIENCE

Development and functions of the choroid plexus–cerebrospinal fluid system

(2015) Melody P. Lun et al.   NATURE REVIEWS NEUROSCIENCE

Switching on cilia: transcriptional networks regulating ciliogenesis

(2014) S. P. Choksi et al.   DEVELOPMENT

Multicilin drives centriole biogenesis via E2f proteins

(2014) L. Ma et al.   GENES & DEVELOPMENT

TAp73 is essential for germ cell adhesion and maturation in testis

(2014) Lena Holembowski et al.   JOURNAL OF CELL BIOLOGY

Cortical hypoplasia and ventriculomegaly of p73-deficient mice: Developmental and adult analysis

(2014) Carolina Medina-Bolívar et al.   JOURNAL OF COMPARATIVE NEUROLOGY

miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110

(2014) Rui Song et al.   NATURE

TAp73 is required for spermatogenesis and the maintenance of male fertility

(2014) Satoshi Inoue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia

(2014) Mieke Boon et al.   Nature Communications

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

New insights into epididymal function in relation to sperm maturation

(2013) Jean-Louis Dacheux et al.   REPRODUCTION

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

MicroRNA-449 and MicroRNA-34b/c Function Redundantly in Murine Testes by Targeting E2F Transcription Factor-Retinoblastoma Protein (E2F-pRb) Pathway

(2012) Jianqiang Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation

(2012) J. L. Stubbs et al.   NATURE CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

MicroRNA-based silencing of Delta/Notch signaling promotes multiple cilia formation

(2011) Brice Marcet et al.   CELL CYCLE

TAp73 is downregulated in oocytes from women of advanced reproductive age

(2011) Maria Rosa Guglielmino et al.   CELL CYCLE

Idas, a Novel Phylogenetically Conserved Geminin-related Protein, Binds to Geminin and Is Required for Cell Cycle Progression

(2011) Dafni-Eleutheria Pefani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

(2011) Brice Marcet et al.   NATURE CELL BIOLOGY

Crosstalk between c-Jun and TAp73α/β contributes to the apoptosis–survival balance

(2011) Max Koeppel et al.   NUCLEIC ACIDS RESEARCH

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

(2011) Marc R. Friedländer et al.   NUCLEIC ACIDS RESEARCH

Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets

(2011) M. Agostini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

(2011) Graciana Diez-Roux et al.   PLOS BIOLOGY

MicroRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia

(2010) Muriel Lizé et al.   CELL CYCLE

Ependymal cells: biology and pathology

(2009) Marc R. Del Bigio   ACTA NEUROPATHOLOGICA

Three-Dimensional Reconstruction of Efferent Ducts in Wild-Type andLgr4Knock-Out Mice

(2009) Marie-Alexandra H. Lambot et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis

(2009) M Lizé et al.   CELL DEATH AND DIFFERENTIATION

Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus

(2009) X. Huang et al.   DEVELOPMENT

miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A

(2009) X. Yang et al.   GENES & DEVELOPMENT

DeltaNp73 regulates neuronal survival in vivo

(2009) F. Tissir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA-449 is a putative regulator of choroid plexus development and function

(2008) Nicholas Redshaw et al.   BRAIN RESEARCH

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

(2008) R. Tomasini et al.   GENES & DEVELOPMENT

Foxj1 transcription factors are master regulators of the motile ciliogenic program

(2008) Xianwen Yu et al.   NATURE GENETICS

Development and Notch Signaling Requirements of the Zebrafish Choroid Plexus

(2008) Brent R. Bill et al.   PLoS One