Article
Chemistry, Applied
Behzad Zakani, Sohrab Entezami, Dana Grecov, Hayder Salem, Ahmad Sedaghat
Summary: In this study, the effect of ultrasonic treatment on the lubrication performance of CNC aqueous suspensions was systematically investigated. The results showed that ultrasonication can significantly reduce the friction coefficient and wear of the lubricant.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Applied
Qingmeng Xu, Fanxing Bu, Chen Sun, Xiao Huang, Hongjie Luo
Summary: Cellulose nanocrystals (CNCs)/DMSO organogels were carefully investigated in this study, and it was found that metal ions played a vital role in organogel formation, similar to hydrogels. The coordination between cations and DMSO alleviated the influence of cation valence on gel mechanical strength. Both CNCs/DMSO and CNCs/H2O gels exhibited instant thixotropic behavior, making them potentially useful for drug delivery applications.
CARBOHYDRATE POLYMERS
(2023)
Article
Engineering, Mechanical
Bo Yu, Kai Wang, Xianjuan Pang, Gensheng Wu, Jibin Pu, Haichao Zhao
Summary: By grafting octadecylamine onto graphene oxide through a simple amidation reaction, ODA-RGO was obtained as a lubricant additive, showing beneficial effects on lubrication and friction-reduction. The excellent tribological behavior was attributed to the formation of a protective film and the restacked shape of ODA-RGO.
TRIBOLOGY INTERNATIONAL
(2022)
Article
Chemistry, Physical
Qing Feng, Fukang Deng, Kangchun Li, Mingyuan Dou, Shuai Zou, Fuchuan Huang
Summary: MXene material Ti3C2 was chemically modified with TDPA to obtain TDPA-Ti3C2, which was dispersed in castor oil. The addition of 0.1 wt% TDPA-Ti3C2 significantly reduced the coefficient of friction and wear rate of the castor oil.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Engineering, Mechanical
Dawit Zenebe Segu, Younghun Chae, Sung-Jun Lee, Chang-Lae Kim
Summary: This study investigates the combined use of nanofluids and laser surface texturing (LST) to improve tribological performance. ZrO2-MoDTC hybrid nanoparticles at different concentrations were added as lubricant additives in base oil. Steel pin surfaces were textured using laser ablation to create microtextured patterns of different shapes and sizes, and their tribological performance was evaluated. Circular dimple textured (DT) surfaces with 0.5 wt% ZrO2-MoDTC hybrid nanofluid demonstrated superior friction reduction and anti-wear performance compared to cross-groove textured (GT) and untextured (UT) surfaces. The average friction coefficient of DT was reduced by approximately 24-28% and 57-60% compared to GT and UT surfaces, respectively. The worn surface analysis indicated excellent tribological performance due to the synergistic effects of the nanofluid and LST.
TRIBOLOGY INTERNATIONAL
(2023)
Article
Engineering, Mechanical
Eduardo Tomanik, Laurent Aubanel, Michael Bussas, Francesco Delloro, Thomas Lampke
Summary: The tribological performance of a thermal sprayed, mirror-like surface with localized protuberances was studied through experiments and computational simulations. The presence of protuberances promoted the quick formation of an antifriction tribofilm, reducing the asperity friction in reciprocating tribological tests. Computer simulations showed that the protuberances reduced hydrodynamic friction by increasing the oil film thickness and reducing the oil film shear rate.
Article
Engineering, Mechanical
Min Ji, Shuhai Liu, Huaping Xiao, Haoyang Li
Summary: This paper investigated the tribological behavior of two synthesized microcapsules filled with ionic liquids as smart tribological additives for water-based drilling mud. The experimental results showed that both microcapsules effectively reduced friction, with a significant decrease in coefficient of friction. The study also demonstrated the correlation between microcapsule responses and load stimuli, suggesting the potential for large-scale applications of smart lubrication.
TRIBOLOGY INTERNATIONAL
(2023)
Article
Engineering, Mechanical
Hongdong Wang, Yue Wang, Yuhong Liu, Jun Zhao, Jinjin Li, Qiang Wang, Jianbin Luo
Summary: Layered double hydroxide (LDH) is a natural mineral that can also be synthetically prepared, known for its unique crystal structure and diverse properties. Research showed that the flower-like LDH sample exhibited the best tribological performance among LDH samples with different morphologies, demonstrating potential for improving lubrication systems.
Review
Chemistry, Multidisciplinary
Mei-Chun Li, Qinglin Wu, Robert J. Moon, Martin A. Hubbe, Michael J. Bortner
Summary: Cellulose nanomaterials, including nanofibrillated cellulose and cellulose nanocrystals, have unique properties such as sustainability, biodegradability, and biocompatibility, making them attractive for a wide range of applications. Their aqueous suspension rheology allows for the creation of viscous suspensions with shear-thinning behavior. These properties make cellulose nanomaterials valuable rheological modifiers in fluid-based applications.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Physical
Chenghong Hu, Xi He, Yunyan Han, Xiangyuan Ye, Mingjin Fan, Feng Zhou, Weimin Liu
Summary: The synthesized 1,4,5,8-4C(n) ester oils exhibit superior thermal and oxidation stability, as well as significant friction reducing and anti-wear properties, making them suitable for steel contact surfaces. These properties are attributed to the strongly and orderly physicochemical adsorption of the molecules on the sliding surfaces.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Engineering, Mechanical
Tuyana Dembelova, Badma Badmaev, Dagzama Makarova, Aleksandr Mashanov, Undrakh Mishigdorzhiyn
Summary: This paper investigates the viscoelastic properties of silicon dioxide nanoparticle suspensions based on polyethylsiloxane by the acoustic resonance method. The shear modulus and the tangent of the mechanical loss angle are calculated. The interaction between polymer molecules and nanoparticles is characterized by infrared spectroscopy. The results show that the addition of silicon dioxide nanoparticles improves the tear strength of the lubricating film and enhances the tribological properties.
Article
Engineering, Chemical
Xiaoliang Ma, Chaoliang Gan, Xiaopeng Li, Yuting Li, Peng Feng, Xiaoqiang Fan, Xiangyuan Ye, Minhao Zhu
Summary: Core-shell structural SiO2@Cu and SiO2@MoS2 microspheres as lubricant additives show improved tribological properties, with SiO2@Cu microspheres outperforming SiO2@MoS2 due to their structural advantage and the synergistic effect of hard SiO2 core and Cu shell.
Article
Engineering, Mechanical
Bader Alqahtani, Wael Hoziefa, Hussein Mohammed Abdel Moneam, Mohamed Hamoud, Sachin Salunkhe, Abou Bakr Elshalakany, Mohamed Abdel-Mottaleb, Joao Paulo Davim
Summary: This paper examines the effects of adding graphene nanoplates to SAE 5W-30 oil on the rheological and tribological properties of the lubricant. The results show that the addition of graphene nanoplates can significantly improve the wear and friction properties of the oil, as well as enhance its thermal conductivity and flashpoint.
Review
Chemistry, Physical
Jia Leang Teh, Rashmi Walvekar, Thachnatharen Nagarajan, Zafar Said, Mohammad Khalid, Nabisab Mujawar Mubarak
Summary: This review presents the recent research on the tribological performance of non -water miscible lubricants. It discusses the tribological properties of various lubricants, such as vegetable oil, blend oil, synthetic oil, ionic liquid, as well as the use of nanoparticles. The findings suggest the need for further research on oil-miscible ionic liquids for mineral, vegetable oils, and nanolubricants. The review also explains the characteristics of nanolubricants, including dispersion stability, viscosity, thermal conductivity, thermal-oxidative stability, and tribological performance. Future recommendations for lubricant research are also discussed.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Physical
Qianqian Jia, Wenjing Sun, Yunyan Han, Mingjin Fan, Desuo Yang, Feng Zhou, Weimin Liu
Summary: The study demonstrates that GAILs exhibit excellent lubricating properties, including better viscosity-temperature characteristics, corrosiveness, and hydrolytic stability, for copper and aluminum friction counterfaces, while traditional halogen-containing ILs are not suitable for these counterfaces.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Engineering, Mechanical
Jinwan Yang, Yuyang Yuan, Ke Li, Tobias Amann, Chun Wang, Chengqing Yuan, Anne Neville
Summary: The study demonstrates that EPND is a promising additive for nematic liquid crystal lubricants, showing potential to reduce surface energy of steel and promote homeotropic alignment of 5CB, leading to excellent lubrication performance, especially in applications with high requirements for low friction.
Article
Chemistry, Multidisciplinary
Yuxia Wang, Zechuan Yu, Alain Dufresne, Zelin Ye, Ning Lin, Ji Zhou
Summary: Nanocellulose, including CNCs and CNFs, is widely utilized as a nano-reinforcing filler for polymeric-based composites due to its high specific modulus. This study introduces a set of theories and methods to evaluate the compatibility and dispersibility of nanocellulose in polymeric matrices, aiming to improve mechanical reinforcement. A promising approach of triple-bond modification on the nanocellulose surface is discussed for accurate recognition in composites.
Article
Chemistry, Applied
Sunan Wang, Ke Li, Tao Xia, Ping Lan, Hui Xu, Ning Lin
Summary: This study successfully applied modified cellulose nanocrystals as a rheological modifier in PFPE lubricating oil, significantly thickening and improving the rheological performance, forming a stable subnetwork based on chain entanglement.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Li Xie, Yue Zhang, Ao Huang, Ji Zhou, Ning Lin, Xiang Lu
Summary: Cellulose nanocrystals (CNC) are rod-like nano-objects derived from natural cellulose with low toxicity and good biocompatibility, widely used in biomedicine as functional additives and nanomaterials. In this study, it was found that TMEs loaded on CNC and TO-CNC surfaces exhibited inhibitory effects on cell activity and proliferation at different concentrations, particularly for Pb2+ and Cd2+ loaded nanocrystals, with cancer cells showing higher sensitivity to these metal elements than normal cells.
MACROMOLECULAR BIOSCIENCE
(2022)
Article
Chemistry, Applied
Jingwen Li, Ning Lin, Chen Du, Yue Ge, Tobias Amann, Hao Feng, Chengqing Yuan, Ke Li
Summary: This study focuses on the application of cellulose nanocrystal (CNC) in greases. The results demonstrate that the addition of CNC within a certain concentration range significantly reduces the friction and wear of the greases. This finding is of great importance for the development of more environmentally friendly lubricant additives.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Multidisciplinary
Mengqin Zhou, Zhenlong Liu, Tongliao Liu, Yan Zhu, Ning Lin
Summary: Chitin nanocrystals (ChNC) are highly crystalline nano-objects found in fungi and shellfish exoskeletons, which have great potential for various applications. In this study, we successfully obtained amino groups on the surface of ChNC through acid hydrolysis and further modified them with fluorescence. The fluorescent-modified ChNC was used as a multifunctional additive in a waterborne polyurethane-based nail polish coating, demonstrating remarkable performance.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Review
Biochemistry & Molecular Biology
Zikang Li, Ge Zhu, Ning Lin
Summary: This review provides a comprehensive summary and exploration of the dispersion characterization of cellulose nanocrystals (CNCs) in polymer matrices, including direct observation, indirect evaluation, and quantified evaluation. Decision tree flowcharts are provided as a reference for selecting appropriate characterization methods.
Article
Biochemistry & Molecular Biology
Yiming Liu, Yan Yang, Yueernisa Tuersun, Wei Du, Yuanhang Xu, Xiaoping Zhao, Ge Zhu, Jingzhi Ma, Ning Lin
Summary: As a renewable and highly crystalline natural polymer nanomaterial, chitin nanocrystals (ChNCs) have attracted significant attention in the field of biomedicine. The structure of ChNCs consists of an acetylglucosamine unit with two hydroxyl groups and one acetyl group. By converting the acetyl group to an active amino group through deacetylation, ChNCs can maintain their rod-like morphology and high crystallinity, which is beneficial for subsequent modification and potential applications. In this study, we investigated the relationship between different treatments and the varied crystallinities of modified ChNCs, which retained high crystallinity while obtaining surface amino groups and aldehyde groups. Natural biomolecules were covalently immobilized on the surface of ChNCs through etherification based on their hydroxyl groups. Carboxyamine and Knoevenagel condensation reactions were achieved on ChNCs using the amino and aldehyde groups. Finally, the modification of ChNCs with natural biomolecules exhibited low or no cytotoxicity, antibacterial properties, and high antioxidant properties, thereby expanding their potential biomedical applications.
Article
Materials Science, Paper & Wood
Yue Ge, Ning Lin, Chen Du, Tobias Amann, Hao Feng, Chengqing Yuan, Ke Li
Summary: The present study aims to explore alternative nanoparticles with higher mechanical strength to replace polytetrafluoroethylene (PTFE) powder as a thickener for fluorine greases. Cellulose nanocrystals (CNCs) were surface modified by grafting fluoropolymer chains and introduced into perfluoropolyether PFPE base oil. The results showed that the obtained polyhexafuorobutyl methacrylate grafted CNC (CNC-g-PHFMA) powder exhibited better friction reduction (11%) and wear resistance (19%) compared to PTFE, indicating a good application prospect for fluoropolymer-grafted CNCs in fluorine greases.
Article
Engineering, Chemical
Jiayang Li, Yuyang Yuan, Tobias Amann, Chengqing Yuan, Ke Li
Summary: The lubricating performance of 1,3-diketone oil was tested on steel surfaces with different roughness grades. Superlubricity was achieved on both smooth and typical engineering surfaces, with the rougher surface showing a shorter running-in time. However, superlubricity was not achieved on the roughest surface due to excessive consumption of oil and large abrasive particles. This study is the first to report oil-based superlubricity on steel surfaces with a roughness of around 200 nm, with potential applications in industry.
Article
Chemistry, Multidisciplinary
Lei Tan, Alain Dufresne, Ge Zhu, Ning Lin
Summary: Receiving considerable interest in recent years, the reducing ends of cellulose nanocrystals (CNCs) have different reactivity from surface chemistry, which contributes to the development of new strategies for modification and performance tailoring. However, the understanding of the phenomena involved at the reducing end is still limited for nanocrystals. This study explores the introduction of aldehyde groups at the reducing end and investigates the influence of the modified species on the crystalline reconfiguration of nanocrystals.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Engineering, Mechanical
Chang Du, Chenxing Sheng, Xingxin Liang, Xiang Rao, Zhiwei Guo
Summary: As an important friction pair in a diesel engine, the cylinder-liner piston ring (CL-PR) operates in a challenging high-temperature environment. In order to understand the relationship between the friction performance of the CL-PR and temperature changes, a reciprocating-friction and wear-testing machine was used to analyze the friction and lubrication performance of four different lubricating oils at various temperatures (room temperature, 60 degrees C, 90 degrees C, and 120 degrees C) based on friction coefficient, contact resistance, and surface topography. The results show that the tribological properties of the lubricating oils exhibit different trends as temperature increases. The friction coefficient of the base oil initially decreases and then increases with temperature, indicating improved friction performance due to a certain temperature rise, as well as the promotion of oxide film formation and reduction in friction coefficient with temperature. On the other hand, the friction coefficient of the other three lubricating oils initially increases and then stabilizes, with the most severe wear observed at 120 degrees C in the form of abrasive wear and adhesive wear.
Article
Polymer Science
Ning Wang, Zikang Li, Ge Zhu, Zechuan Yu, Renyuan Qin, Ji Zhou, Ning Lin
Summary: This study investigates the influence of surface modification on nanoparticles on the mechanical performance of composites. By using surface-modified cellulose nanocrystals (CNCs) and castor oil-based polyurethane (PU) as a composite system, it is found that the compatibility between modified CNCs and PU affects the microstructure and mechanical properties of the composites. The modified CNCs can effectively enhance the strength and rigidity of the composite materials.
Article
Engineering, Mechanical
Yuwen Xu, Zhongmin Nie, Junsheng Li, Chen Du, Tobias Amann, Chengqing Yuan, Ke Li
Summary: In this study, polydopamine-coated silica nanoparticles were dispersed in 1,3-diketone oil to enhance its superlubricity on steel surfaces. The functionalized nanoparticles repaired surface pits on the steel substrate, leading to shorter running-in time and smaller wear. This modification allowed the superlubricity region of 1,3-diketone to extend beyond its original load and velocity boundaries.
TRIBOLOGY INTERNATIONAL
(2023)
Article
Chemistry, Multidisciplinary
Ziyi Xu, Ji Zhou, Dan Li, Ge Zhu, Ning Lin
Summary: This study investigates the covalent grafting of polyaniline (PANI) onto cellulose nanocrystals (CNCs) to prepare composite conductive fibers with improved properties. The wet spinning process resulted in fibers with good tensile strength, electrical conductivity, and flexibility. These composite fibers have potential applications in antistatic textiles and the electronic industry.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)