A novel orally administered trimebutine compound (GIC-1001) is anti-nociceptive and features peripheral opioid agonistic activity and Hydrogen Sulphide-releasing capacity in mice
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A novel orally administered trimebutine compound (GIC-1001) is anti-nociceptive and features peripheral opioid agonistic activity and Hydrogen Sulphide-releasing capacity in mice
Authors
Keywords
-
Journal
EUROPEAN JOURNAL OF PAIN
Volume 20, Issue 5, Pages 723-730
Publisher
Wiley
Online
2015-11-06
DOI
10.1002/ejp.798
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hydrogen sulfide inhibits homocysteine-induced endoplasmic reticulum stress and neuronal apoptosis in rat hippocampus via upregulation of the BDNF-TrkB pathway
- (2014) Hai-jun Wei et al. ACTA PHARMACOLOGICA SINICA
- Safety, Tolerability and Pharmacokinetics of Trimebutine 3-Thiocarbamoylbenzenesulfonate (GIC-1001) in a Randomized Phase I Integrated Design Study: Single and Multiple Ascending Doses and Effect of Food in Healthy Volunteers
- (2014) Jean-Michel Paquette et al. CLINICAL THERAPEUTICS
- Carbon Monoxide, Hydrogen Sulfide, and Nitric Oxide as Signaling Molecules in the Gastrointestinal Tract
- (2014) Gianrico Farrugia et al. GASTROENTEROLOGY
- The physiological role of hydrogen sulfide and beyond
- (2014) Hideo Kimura NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- Hydrogen Sulfide Signaling in the Gastrointestinal Tract
- (2013) David R. Linden ANTIOXIDANTS & REDOX SIGNALING
- Current and future pharmacological treatments for diarrhea-predominant irritable bowel syndrome
- (2013) Michael Camilleri EXPERT OPINION ON PHARMACOTHERAPY
- Eluxadoline Benefits Patients With Irritable Bowel Syndrome With Diarrhea in a Phase 2 Study
- (2013) Leonard S. Dove et al. GASTROENTEROLOGY
- Potentiation of TRPV4 signalling by histamine and serotonin: an important mechanism for visceral hypersensitivity
- (2010) N. Cenac et al. GUT
- Hydrogen Sulphide Induces μ Opioid Receptor-Dependent Analgesia in a Rodent Model of Visceral Pain
- (2010) Eleonora Distrutti et al. Molecular Pain
- Endogenous Production of H2S in the Gastrointestinal Tract: Still in Search of a Physiologic Function
- (2009) David R. Linden et al. ANTIOXIDANTS & REDOX SIGNALING
- The Endogenous Hydrogen Sulfide Producing Enzyme Cystathionine-β Synthase Contributes to Visceral Hypersensitivity in a Rat Model of Irritable Bowel Syndrome
- (2009) Guang-Yin Xu et al. Molecular Pain
- A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats
- (2009) Eleonora Distrutti et al. PHARMACOLOGICAL RESEARCH
- Clinical trial: asimadoline in the treatment of patients with irritable bowel syndrome
- (2008) A. W. MANGEL et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- T1456 Histamine and Serotonin Sensitizes the Transient Receptor Potential Vanilloid Receptor 4 to Induce Visceral Allodynia and Hyperalgesia
- (2008) Nicolas Cenac et al. GASTROENTEROLOGY
- Novel pharmacology: asimadoline, a κ-opioid agonist, and visceral sensation
- (2008) m. camilleri NEUROGASTROENTEROLOGY AND MOTILITY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started