Lipid mediators in immune regulation and resolution

The oxidized linoleic acid metabolite 12,13-DiHOME mediates thermal hyperalgesia during inflammatory pain

(2018) Béla Zimmer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia

(2018) Matthew L. Edin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer’s Disease

(2018) Ju Youn Lee et al.   Nature Communications

Effects of docosahexaenoic acid–rich n−3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study

(2018) Inger Vedin et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

(2017) Simon D Harding et al.   NUCLEIC ACIDS RESEARCH

Prolonged immune alteration following resolution of acute inflammation in humans

(2017) Madhur P. Motwani et al.   PLoS One

Inflammatory Resolution Triggers a Prolonged Phase of Immune Suppression through COX-1/mPGES-1-Derived Prostaglandin E 2

(2017) Justine Newson et al.   Cell Reports

CYP450-derived oxylipins mediate inflammatory resolution

(2016) Derek W. Gilroy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of resolvin D2 receptor mediating resolution of infections and organ protection

(2015) Nan Chiang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipid-Metabolizing CYPs in the Regulation and Dysregulation of Metabolism

(2014) David Bishop-Bailey et al.   Annual Review of Nutrition

Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective

(2014) Raja-Elie E. Abdulnour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rationally Designed Multitarget Agents Against Inflammation and Pain

(2013) S. H. Hwang et al.   CURRENT MEDICINAL CHEMISTRY

Nutritional lipidomics: Molecular metabolism, analytics, and diagnostics

(2013) Jennifer T. Smilowitz et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inducible CYP2J2 and Its Product 11,12-EET Promotes Bacterial Phagocytosis: A Role for CYP2J2 Deficiency in the Pathogenesis of Crohn’s Disease?

(2013) Jonas Bystrom et al.   PLoS One

Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice

(2012) Ketul R. Chaudhary et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Endogenous Epoxygenases Are Modulators of Monocyte/Macrophage Activity

(2011) Jonas Bystrom et al.   PLoS One

Soluble Epoxide Hydrolase Deficiency Attenuates Neointima Formation in the Femoral Cuff Model of Hyperlipidemic Mice

(2010) Marc Revermann et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways

(2010) T. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

(2010) S. Krishnamoorthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Soluble Epoxide Hydrolase Attenuated Atherosclerosis, Abdominal Aortic Aneurysm Formation, and Dyslipidemia

(2009) Le-Ning Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats

(2009) Marc Revermann et al.   JOURNAL OF HYPERTENSION

Effects of Low-Dose Aspirin on Acute Inflammatory Responses in Humans

(2009) T. Morris et al.   JOURNAL OF IMMUNOLOGY

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis

(2009) Matthew Spite et al.   NATURE

Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets

(2008) M. Dona et al.   BLOOD

Synthetic chemerin-derived peptides suppress inflammation through ChemR23

(2008) Jenna L. Cash et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epoxyeicosatrienoic Acids Function as Selective, Endogenous Antagonists of Native Thromboxane Receptors: Identification of a Novel Mechanism of Vasodilation

(2008) D. J. Behm et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Role of Dose Potency in the Prediction of Risk of Myocardial Infarction Associated With Nonsteroidal Anti-Inflammatory Drugs in the General Population

(2008) Luis Alberto García Rodríguez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways

(2008) B. Inceoglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems approach with inflammatory exudates uncovers novel anti-inflammatory and pro-resolving mediators

(2008) Charles N. Serhan   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS