miR-140-5p induces cell apoptosis and decreases Warburg effect in chronic myeloid leukemia by targeting SIX1

Transcriptional Regulation of the Warburg Effect in Cancer by SIX1

(2018) Ling Li et al.   CANCER CELL

MiR-139-5p is associated with poor prognosis and regulates glycolysis by repressing PKM2 in gallbladder carcinoma

(2018) Jianan Chen et al.   CELL PROLIFERATION

Silencing of miR-193a-5p increases the chemosensitivity of prostate cancer cells to docetaxel

(2017) Zhan Yang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

miR-140-5p suppresses the proliferation, migration and invasion of gastric cancer by regulating YES1

(2017) Zheng Fang et al.   Molecular Cancer

Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia

(2017) Andreas Hochhaus et al.   NEW ENGLAND JOURNAL OF MEDICINE

SIX1 overexpression predicts poor prognosis and induces radioresistance through AKT signaling in esophageal squamous cell carcinoma

(2017) Zheng He et al.   OncoTargets and Therapy

MicroRNA-140-5p targets insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1) to suppress cervical cancer growth and metastasis

(2016) Yanlin Su et al.   Oncotarget

miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells

(2015) Zhan Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

miR-140-5p inhibits ovarian cancer growth partially by repression of PDGFRA

(2015) Hong Lan et al.   BIOMEDICINE & PHARMACOTHERAPY

PKM2 contributes to cancer metabolism

(2015) Nicholas Wong et al.   CANCER LETTERS

ERK2-Pyruvate Kinase Axis Permits Phorbol 12-Myristate 13-Acetate-induced Megakaryocyte Differentiation in K562 Cells

(2015) Noor Chaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MiR-362-5p promotes the malignancy of chronic myelocytic leukaemia via down-regulation of GADD45α

(2015) Peng Yang et al.   Molecular Cancer

MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma

(2015) QIURAN XU et al.   ONCOLOGY REPORTS

MicroRNA-320a acts as a tumor suppressor by targeting BCR/ABL oncogene in chronic myeloid leukemia

(2015) Zhu Xishan et al.   Scientific Reports

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers

(2015) Shruti Desai et al.   Oncotarget

MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors

(2014) L.-S. Wang et al.   BLOOD

MicroRNAome genome: A treasure for cancer diagnosis and therapy

(2014) Ioana Berindan-Neagoe et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Down-Regulation of miR-140 Induces EMT and Promotes Invasion by Targeting Slug in Esophageal Cancer

(2014) Weiling Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-140-5p suppresses tumor growth and metastasis by targeting transforming growth factor β receptor 1 and fibroblast growth factor 9 in hepatocellular carcinoma

(2013) Hao Yang et al.   HEPATOLOGY

Targeting lactate metabolism for cancer therapeutics

(2013) Joanne R. Doherty et al.   JOURNAL OF CLINICAL INVESTIGATION

Six1 Promotes Proliferation of Pancreatic Cancer Cells via Upregulation of Cyclin D1 Expression

(2013) Zhaoming Li et al.   PLoS One

SIX1 promotes epithelial–mesenchymal transition in colorectal cancer through ZEB1 activation

(2012) H Ono et al.   ONCOGENE

Expression patterns of microRNAs associated with CML phases and their disease related targets

(2011) Kateřina Machová Poláková et al.   Molecular Cancer

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth

(2011) Q. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

(2009) Charles J. David et al.   NATURE

Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis

(2009) X Liu et al.   ONCOGENE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The sine oculis homeobox (SIX) family of transcription factors as regulators of development and disease

(2008) J. P. Kumar   CELLULAR AND MOLECULAR LIFE SCIENCES