Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site

Published 2018 View Full Article

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Title
Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site
Authors
Keywords
Tubulin inhibitor, Vinyl sulfone, Indole, Colchicine site, Drug-likeness
Journal
BIOORGANIC CHEMISTRY
Volume 85, Issue -, Pages 49-59
Publisher
Elsevier BV
Online
2018-12-11
DOI
10.1016/j.bioorg.2018.12.015

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