Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site

标题
Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site
作者
关键词
Tubulin inhibitor, Vinyl sulfone, Indole, Colchicine site, Drug-likeness
出版物
BIOORGANIC CHEMISTRY
Volume 85, Issue -, Pages 49-59
出版商
Elsevier BV
发表日期
2018-12-11
DOI
10.1016/j.bioorg.2018.12.015

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