Revealing the Origins of Foam Cells in Atherosclerotic Lesions

Letter by Cochain et al Regarding Article, “Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models”

(2019) Clément Cochain et al.   CIRCULATION RESEARCH

Smooth Muscle Cells Contribute the Majority of Foam Cells in ApoE (Apolipoprotein E)-Deficient Mouse Atherosclerosis

(2019) Ying Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial–mesenchymal transition in atherosclerosis

(2018) Celine Souilhol et al.   CARDIOVASCULAR RESEARCH

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine AtherosclerosisNovelty and Significance

(2018) Clément Cochain et al.   CIRCULATION RESEARCH

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass CytometryNovelty and Significance

(2018) Holger Winkels et al.   CIRCULATION RESEARCH

Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice

(2018) Delphine Gomez et al.   NATURE MEDICINE

Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models

(2018) Kyeongdae Kim et al.   CIRCULATION RESEARCH

Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury

(2017) Ying-Ying Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective

(2016) Olga A Cherepanova et al.   NATURE MEDICINE

Endothelial-to-mesenchymal transition drives atherosclerosis progression

(2015) Pei-Yu Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammation and plaque vulnerability

(2015) G. K. Hansson et al.   JOURNAL OF INTERNAL MEDICINE

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

(2015) Laura S Shankman et al.   NATURE MEDICINE

Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis

(2014) Sima Allahverdian et al.   CIRCULATION

Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis

(2014) Susanne Feil et al.   CIRCULATION RESEARCH

Detection of histone modifications at specific gene loci in single cells in histological sections

(2013) Delphine Gomez et al.   NATURE METHODS

Smooth muscle cell phenotypic switching in atherosclerosis

(2012) D. Gomez et al.   CARDIOVASCULAR RESEARCH

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE