Curcumin induces apoptotic cell death and protective autophagy by inhibiting AKT/mTOR/p70S6K pathway in human ovarian cancer cells

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Screening for Ovarian Cancer

(2018) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2

(2018) Sourav Banerjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimizing treatment in recurrent epithelial ovarian cancer

(2017) Giacomo Corrado et al.   Expert Review of Anticancer Therapy

Cisplatin induces protective autophagy through activation of BECN1 in human bladder cancer cells

(2017) Ji-Fan Lin et al.   Drug Design Development and Therapy

Curcumin Inhibits Apoptosis of Chondrocytes through Activation ERK1/2 Signaling Pathways Induced Autophagy

(2017) Xiaodong Li et al.   Nutrients

Endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance in human ovarian cancer cells

(2017) Jin-Long Hu et al.   Oncotarget

Altered Cell to Cell Communication, Autophagy and Mitochondrial Dysfunction in a Model of Hepatocellular Carcinoma: Potential Protective Effects of Curcumin and Stem Cell Therapy

(2016) Ola M Tork et al.   Asian Pacific Journal of Cancer Prevention

Novel mechanisms and approaches to overcome multidrug resistance in the treatment of ovarian cancer

(2016) Fang Ren et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Autophagy as a target for hematological malignancy therapy

(2016) Zhiwu Dong et al.   BLOOD REVIEWS

Interfering EZH2 Expression Reverses the Cisplatin Resistance in Human Ovarian Cancer by Inhibiting Autophagy

(2016) Yang Sun et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Curcumin induces apoptosis by inhibiting sarco/endoplasmic reticulum Ca2+ ATPase activity in ovarian cancer cells

(2016) Jeong-ah Seo et al.   CANCER LETTERS

Curcumin activates autophagy and attenuates oxidative damage in EA.hy926 cells via the Akt/mTOR pathway

(2016) SHOUYU GUO et al.   Molecular Medicine Reports

Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids

(2016) Misi He et al.   Oncotarget

In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line

(2016) Jigang Wang et al.   Scientific Reports

Curcumin Suppresses Proliferation and Migration of MDA-MB-231 Breast Cancer Cells through Autophagy-Dependent Akt Degradation

(2016) Feng Guan et al.   PLoS One

TXNDC17 promotes paclitaxel resistance via inducing autophagy in ovarian cancer

(2015) Song-Fa Zhang et al.   Autophagy

Polymeric nanoassemblies entrapping curcumin overcome multidrug resistance in ovarian cancer

(2015) Qiheng Gou et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Curcumin induces autophagy, inhibits proliferation and invasion by downregulating AKT/mTOR signaling pathway in human melanoma cells

(2015) GUANGMING ZHAO et al.   ONCOLOGY REPORTS

B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy

(2015) Fang-Yuan Shao et al.   Oncotarget

PI3K/AKT/mTOR signaling pathway as a therapeutic target for ovarian cancer

(2014) HaiXia Li et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Curcumin Promotes Autophagic Survival of a Subset of Colon Cancer Stem Cells, Which Are Ablated by DCLK1-siRNA

(2014) C. Kantara et al.   CANCER RESEARCH

Potential Application of Curcumin and Its Analogues in the Treatment Strategy of Patients with Primary Epithelial Ovarian Cancer

(2014) Katarzyna Terlikowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transferrin-Targeted Polymeric Micelles Co-loaded with Curcumin and Paclitaxel: Efficient Killing of Paclitaxel-Resistant Cancer Cells

(2014) Abraham H. Abouzeid et al.   PHARMACEUTICAL RESEARCH

B19, a Novel Monocarbonyl Analogue of Curcumin, Induces Human Ovarian Cancer Cell Apoptosis via Activation of Endoplasmic Reticulum Stress and the Autophagy Signaling Pathway

(2013) Wanglei Qu et al.   International Journal of Biological Sciences

Curcumin Induces Cross-Regulation Between Autophagy and Apoptosis in Uterine Leiomyosarcoma Cells

(2013) Bin Li et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Polymeric Mixed Micelles for Delivery of Curcumin to Multidrug Resistant Ovarian Cancer

(2013) Vipin Saxena et al.   Journal of Biomedical Nanotechnology

Curcumin-induced autophagy contributes to the decreased survival of oral cancer cells

(2012) Ji Young Kim et al.   ARCHIVES OF ORAL BIOLOGY

Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy

(2012) Paola Maycotte et al.   Autophagy

A novel mono-carbonyl analogue of curcumin induces apoptosis in ovarian carcinoma cells via endoplasmic reticulum stress and reactive oxygen species production

(2011) Jian Xiao   Molecular Medicine Reports

Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells

(2010) Kazuhito Sasaki et al.   BMC CANCER

Curcumin Selectively Induces Apoptosis in Cutaneous T-Cell Lymphoma Cell Lines and Patients’ PBMCs: Potential Role for STAT-3 and NF-κB Signaling

(2010) Chunlei Zhang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Curcumin induces apoptosis-independent death in oesophageal cancer cells

(2009) G O'Sullivan-Coyne et al.   BRITISH JOURNAL OF CANCER

Chloroquine and its analogs: A new promise of an old drug for effective and safe cancer therapies

(2009) V. Raja Solomon et al.   EUROPEAN JOURNAL OF PHARMACOLOGY