Modulation of CD95-mediated signaling by post-translational modifications: towards understanding CD95 signaling networks

The tyrosine phosphorylated pro-survival form of Fas intensifies the EGF-induced signal in colorectal cancer cells through the nuclear EGFR/STAT3-mediated pathway

(2018) Ngoc Ly Ta et al.   Scientific Reports

Quantitative single cell analysis uncovers the life/death decision in CD95 network

(2018) Jörn H. Buchbinder et al.   PLoS Computational Biology

Drug resistance related to aberrant glycosylation in colorectal cancer

(2017) Ninon Very et al.   Oncotarget

Cell death-independent activities of the death receptors CD95, TRAILR1, and TRAILR2

(2016) Daniela Siegmund et al.   FEBS Journal

Hallmarks of glycosylation in cancer

(2016) Jennifer Munkley et al.   Oncotarget

An Evolution-Guided Analysis Reveals a Multi-Signaling Regulation of Fas by Tyrosine Phosphorylation and its Implication in Human Cancers

(2016) Krittalak Chakrabandhu et al.   PLOS BIOLOGY

Fas Versatile Signaling and Beyond: Pivotal Role of Tyrosine Phosphorylation in Context-Dependent Signaling and Diseases

(2016) Krittalak Chakrabandhu et al.   Frontiers in Immunology

Fas palmitoylation by the palmitoyl acyltransferase DHHC7 regulates Fas stability

(2014) A Rossin et al.   CELL DEATH AND DIFFERENTIATION

Systems biology of death receptor networks: live and let die

(2014) I N Lavrik   Cell Death & Disease

Glycobiology of cell death: when glycans and lectins govern cell fate

(2013) R G Lichtenstein et al.   CELL DEATH AND DIFFERENTIATION

What does S-palmitoylation do to membrane proteins?

(2013) Sanja Blaskovic et al.   FEBS Journal

Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells

(2013) Sean P. Cullen et al.   MOLECULAR CELL

Structural determinants of DISC function: New insights into death receptor-mediated apoptosis signalling

(2013) Tamas Sessler et al.   PHARMACOLOGY & THERAPEUTICS

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

(2012) Laura S. Dickens et al.   MOLECULAR CELL

Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model

(2012) Kolja Schleich et al.   MOLECULAR CELL

Tyrosine phosphorylation and CD95: A FAScinating switch

(2011) Ignacio Sancho-Martinez et al.   CELL CYCLE

Regulation of CD95/Fas signaling at the DISC

(2011) I N Lavrik et al.   CELL DEATH AND DIFFERENTIATION

S-Nitrosylation of the Death Receptor Fas Promotes Fas Ligand–Mediated Apoptosis in Cancer Cells

(2011) Lissbeth Leon-Bollotte et al.   GASTROENTEROLOGY

Calmodulin Mediates Fas-induced FADD-independent Survival Signaling in Pancreatic Cancer Cells via Activation of Src-Extracellular Signal-regulated Kinase (ERK)

(2011) Kaiyu Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialylation of the Fas Death Receptor by ST6Gal-I Provides Protection against Fas-mediated Apoptosis in Colon Carcinoma Cells

(2011) Amanda F. Swindall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of the CD95-Induced Apoptosis: The Role of CD95 N-Glycosylation

(2011) Olga M. Shatnyeva et al.   PLoS One

Regulation of apoptosis through cysteine oxidation: implications for fibrotic lung disease

(2010) Yvonne M.W. Janssen-Heininger et al.   Annals of the New York Academy of Sciences

CD95-Ligand on Peripheral Myeloid Cells Activates Syk Kinase to Trigger Their Recruitment to the Inflammatory Site

(2010) Elisabeth Letellier et al.   IMMUNITY

SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity

(2010) E Charlier et al.   LEUKEMIA

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells

(2010) Leo Neumann et al.   Molecular Systems Biology

Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling

(2009) Zhaoyu Jin et al.   CELL

The Death Receptor CD95 Activates Adult Neural Stem Cells for Working Memory Formation and Brain Repair

(2009) Nina S. Corsini et al.   Cell Stem Cell

Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas

(2009) Vikas Anathy et al.   JOURNAL OF CELL BIOLOGY

A New C-Terminal Cleavage Product of Procaspase-8, p30, Defines an Alternative Pathway of Procaspase-8 Activation

(2009) J. C. Hoffmann et al.   MOLECULAR AND CELLULAR BIOLOGY

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

(2009) Lorraine A. O’ Reilly et al.   NATURE

Regulation of CD95/APO-1/Fas-induced apoptosis by protein phosphatases

(2008) Geoffrey Gloire et al.   BIOCHEMICAL PHARMACOLOGY

Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma

(2008) Susanne Kleber et al.   CANCER CELL

Role of S-nitrosylation in apoptosis resistance and carcinogenesis

(2008) Anand Krishnan V. Iyer et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY