Tumor Heterogeneity Correlates with Less Immune Response and Worse Survival in Breast Cancer Patients

Cytolytic Activity Score to Assess Anticancer Immunity in Colorectal Cancer

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Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer

(2018) Linda S Lindström et al.   JNCI-Journal of the National Cancer Institute

Ceramide species are elevated in human breast cancer and are associated with less aggressiveness

(2018) Kazuki Moro et al.   Oncotarget

Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer

(2018) Linda S Lindström et al.   JNCI-Journal of the National Cancer Institute

Novel MicroRNA-Based Risk Score Identified by Integrated Analyses to Predict Metastasis and Poor Prognosis in Breast Cancer

(2018) Tstutomu Kawaguchi et al.   ANNALS OF SURGICAL ONCOLOGY

ASO Author Reflections: “From Computer to Bedside”: A New Translational Approach to Immunogenomics

(2018) Tsutomu Kawaguchi et al.   ANNALS OF SURGICAL ONCOLOGY

Paradoxical Association of Postoperative Plasma Sphingosine-1-Phosphate with Breast Cancer Aggressiveness and Chemotherapy

(2017) Rajesh Ramanathan et al.   MEDIATORS OF INFLAMMATION

Determining the optimal number and location of cutoff points with application to data of cervical cancer

(2017) Chung Chang et al.   PLoS One

Molecular heterogeneity in breast cancer: State of the science and implications for patient care

(2017) Rachel E. Ellsworth et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tamoxifen sensitivity-related microRNA-342 is a useful biomarker for breast cancer survival

(2017) Jessica Young et al.   Oncotarget

Overexpression of suppressive microRNAs, miR-30a and miR-200c are associated with improved survival of breast cancer patients

(2017) Tsutomu Kawaguchi et al.   Scientific Reports

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

(2017) Pornpimol Charoentong et al.   Cell Reports

Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

(2016) Giampaolo Bianchini et al.   Nature Reviews Clinical Oncology

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

(2016) N. McGranahan et al.   SCIENCE

Pan-cancer analysis of intratumor heterogeneity as a prognostic determinant of survival

(2016) Luc G.T. Morris et al.   Oncotarget

Pan-cancer analysis of the extent and consequences of intratumor heterogeneity

(2015) Noemi Andor et al.   NATURE MEDICINE

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Correction: Intra-tumor Genetic Heterogeneity and Mortality in Head and Neck Cancer: Analysis of Data from The Cancer Genome Atlas

(2015)   PLOS MEDICINE

Single-Cell Genetic Analysis Using Automated Microfluidics to Resolve Somatic Mosaicism

(2015) Keith E. Szulwach et al.   PLoS One

Adenosine A2A Receptors Intrinsically Regulate CD8+ T Cells in the Tumor Microenvironment

(2014) C. Cekic et al.   CANCER RESEARCH

PyClone: statistical inference of clonal population structure in cancer

(2014) Andrew Roth et al.   NATURE METHODS

VISTA Is a Novel Broad-Spectrum Negative Checkpoint Regulator for Cancer Immunotherapy

(2014) J. L. Lines et al.   Cancer Immunology Research

CD4+ follicular helper T cell infiltration predicts breast cancer survival

(2013) Chunyan Gu-Trantien et al.   JOURNAL OF CLINICAL INVESTIGATION

The causes and consequences of genetic heterogeneity in cancer evolution

(2013) Rebecca A. Burrell et al.   NATURE

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

THetA: inferring intra-tumor heterogeneity from high-throughput DNA sequencing data

(2013) Layla Oesper et al.   GENOME BIOLOGY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Absolute quantification of somatic DNA alterations in human cancer

(2012) Scott L Carter et al.   NATURE BIOTECHNOLOGY

MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma

(2012) Edmund A. Mroz et al.   ORAL ONCOLOGY

Cutoff Finder: A Comprehensive and Straightforward Web Application Enabling Rapid Biomarker Cutoff Optimization

(2012) Jan Budczies et al.   PLoS One

Indoleamine 2,3 dioxygenase and metabolic control of immune responses

(2012) David H. Munn et al.   TRENDS IN IMMUNOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery