Cytolytic Activity Score to Assess Anticancer Immunity in Colorectal Cancer

Origins of natural killer cell memory: special creation or adaptive evolution

(2018) Kayla A. Holder et al.   IMMUNOLOGY

The PD-1 expressing immune phenotype of T cell exhaustion is prominent in the ‘immunoreactive’ microenvironment of colorectal carcinoma

(2017) Friedrich Prall et al.   HISTOPATHOLOGY

Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer

(2017) Inés Mármol et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Vascular endothelial growth factor A amplification in colorectal cancer is associated with reduced M1 and M2 macrophages and diminished PD-1-expressing lymphocytes

(2017) Katharina Burmeister et al.   PLoS One

Primary Tr1 cells from metastatic melanoma eliminate tumor-promoting macrophages through granzyme B- and perforin-dependent mechanisms

(2017) Hongxia Yan et al.   TUMOR BIOLOGY

Overexpression of suppressive microRNAs, miR-30a and miR-200c are associated with improved survival of breast cancer patients

(2017) Tsutomu Kawaguchi et al.   Scientific Reports

Clinical Impact of Tumor DNA Repair Expression and T-cell Infiltration in Breast Cancers

(2017) Andrew R. Green et al.   Cancer Immunology Research

Targeted Cell-to-Cell Delivery of Protein Payloads via the Granzyme-Perforin Pathway

(2017) Daniel J. Woodsworth et al.   Molecular Therapy-Methods & Clinical Development

A relationship to survival is seen by combining the factors of mismatch repair status, tumor location and age of onset in colorectal cancer patients

(2017) Pan Li et al.   PLoS One

Number of Intratumoral T Lymphocytes Is Associated With Lymph Node Size, Lymph Node Harvest, and Outcome in Node-Negative Colon Cancer

(2016) Bruno Märkl et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment

(2016) James H Park et al.   BRITISH JOURNAL OF CANCER

Immune Cytolytic Activity Stratifies Molecular Subsets of Human Pancreatic Cancer

(2016) David Balli et al.   CLINICAL CANCER RESEARCH

The Potential Value of Immunotherapy in Colorectal Cancers: Review of the Evidence for Programmed Death-1 Inhibitor Therapy

(2016) James W.T. Toh et al.   Clinical Colorectal Cancer

Prognostic impact of tumour-infiltrating B cells and plasma cells in colorectal cancer

(2016) Jonna Berntsson et al.   INTERNATIONAL JOURNAL OF CANCER

Implication of programmed cell death ligand 1 expression in tumor recurrence and prognosis in rectal cancer with neoadjuvant chemoradiotherapy

(2016) Susumu Saigusa et al.   International Journal of Clinical Oncology

Patterns and prognostic relevance of PD-1 and PD-L1 expression in colorectal carcinoma

(2016) Lik Hang Lee et al.   MODERN PATHOLOGY

Classification and characterization of microsatellite instability across 18 cancer types

(2016) Ronald J Hause et al.   NATURE MEDICINE

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

(2016) Marios Giannakis et al.   Cell Reports

Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study

(2016) H. Raza Ali et al.   PLOS MEDICINE

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

(2015) Dung T. Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data

(2015) Antonio Colaprico et al.   NUCLEIC ACIDS RESEARCH

The Evolving Role of Immune Checkpoint Inhibitors in Cancer Treatment

(2015) G. K. Pennock et al.   ONCOLOGIST

High Frequency of CD8 Positive Lymphocyte Infiltration Correlates with Lack of Lymph Node Involvement in Early Rectal Cancer

(2014) Silvio Däster et al.   DISEASE MARKERS

Tim-3: An Emerging Target in the Cancer Immunotherapy Landscape

(2014) A. C. Anderson   Cancer Immunology Research

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Regulatory T Cell Infiltration Predicts Outcome Following Resection of Colorectal Cancer Liver Metastases

(2012) Steven C. Katz et al.   ANNALS OF SURGICAL ONCOLOGY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Memory CD4 T cells: generation, reactivation and re-assignment

(2010) Megan K.L. MacLeod et al.   IMMUNOLOGY

Activation of cytotoxic T-cell receptor    T lymphocytes in response to specific stimulation in myelodysplastic syndromes

(2008) J.-J. Kiladjian et al.   HAEMATOLOGICA

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

(2008) Paul Salama et al.   JOURNAL OF CLINICAL ONCOLOGY