The platelet NLRP3 inflammasome is upregulated in a murine model of pancreatic cancer and promotes platelet aggregation and tumor growth

Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps

(2018) Brian A. Boone et al.   BMC CANCER

Platelets at the crossroads of thrombosis, inflammation and haemolysis

(2018) Sebastian Vogel et al.   BRITISH JOURNAL OF HAEMATOLOGY

Annual Report to the Nation on the Status of Cancer, part I: National cancer statistics

(2018) Kathleen A. Cronin et al.   CANCER

NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis

(2018) Jianlin Qiao et al.   HAEMATOLOGICA

Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3

(2018) Hao Hu et al.   Molecular Cancer

NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis

(2018) Jianlin Qiao et al.   HAEMATOLOGICA

Role of the NLRP3 inflammasome in cancer

(2018) Maryam Moossavi et al.   Molecular Cancer

Human NACHT, LRR, and PYD domain–containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase

(2017) Xiao Liu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NLRP3 inflammasome activation promotes inflammation-induced carcinogenesis in head and neck squamous cell carcinoma

(2017) Cong-Fa Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma

(2017) Donnele Daley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MiR-22 sustains NLRP3 expression and attenuates H. pylori-induced gastric carcinogenesis

(2017) S Li et al.   ONCOGENE

Incidence, outcome and risk stratification tools for venous thromboembolism in advanced pancreatic cancer – A retrospective cohort study

(2017) Stephan Kruger et al.   THROMBOSIS RESEARCH

P2X7 receptor and NLRP3 inflammasome activation in head and neck cancer

(2017) Ju Young Bae et al.   Oncotarget

Inflammasomes in Inflammation-Induced Cancer

(2017) Chu Lin et al.   Frontiers in Immunology

Preoperative platelet lymphocyte ratio as independent predictors of prognosis in pancreatic cancer: A systematic review and meta-analysis

(2017) Wei Song et al.   PLoS One

Aspirin Use and Reduced Risk of Pancreatic Cancer

(2016) Harvey A. Risch et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Activation of NLRP3 inflammasome enhances the proliferation and migration of A549 lung cancer cells

(2016) YANLI WANG et al.   ONCOLOGY REPORTS

Platelets at the interface of thrombosis, inflammation, and cancer

(2015) A. T. Franco et al.   BLOOD

Ibrutinib Exerts Potent Antifibrotic and Antitumor Activities in Mouse Models of Pancreatic Adenocarcinoma

(2015) D. Masso-Valles et al.   CANCER RESEARCH

Nucleotide-Binding Oligomerization Domain 2 Receptor Is Expressed in Platelets and Enhances Platelet Activation and ThrombosisCLINICAL PERSPECTIVE

(2015) Si Zhang et al.   CIRCULATION

Platelet-derived HMGB1 is a critical mediator of thrombosis

(2015) Sebastian Vogel et al.   JOURNAL OF CLINICAL INVESTIGATION

Bruton’s tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury

(2015) Minako Ito et al.   Nature Communications

Emerging roles for platelets as immune and inflammatory cells

(2014) C. N. Morrell et al.   BLOOD

Toll-Like Receptor 4 Regulates Platelet Function and Contributes to Coagulation Abnormality and Organ Injury in Hemorrhagic Shock and Resuscitation

(2014) N. Ding et al.   Circulation-Cardiovascular Genetics

Platelets guide the formation of early metastatic niches

(2014) M. Labelle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation

(2013) E. D. Hottz et al.   BLOOD

NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice

(2012) M. Kovarova et al.   JOURNAL OF IMMUNOLOGY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Pancreatitis-Induced Inflammation Contributes to Pancreatic Cancer by Inhibiting Oncogene-Induced Senescence

(2011) Carmen Guerra et al.   CANCER CELL