Depletion of PD-1-positive cells ameliorates autoimmune disease

An Albumin-binding Polypeptide Both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells

(2018) Peng Wang et al.   Theranostics

An Anti-Programmed Death-1 Antibody (αPD-1) Fusion Protein That Self-Assembles into a Multivalent and Functional αPD-1 Nanoparticle

(2017) Peng Zhao et al.   MOLECULAR PHARMACEUTICS

Nivolumab-induced autoimmune diabetes mellitus presenting as diabetic ketoacidosis in a patient with metastatic lung cancer

(2017) James Luke Godwin et al.   Journal for ImmunoTherapy of Cancer

Novel Agents for Relapsing Forms of Multiple Sclerosis

(2016) Rebecca Straus Farber et al.   Annual Review of Medicine

Co-stimulatory and Co-inhibitory Pathways in Autoimmunity

(2016) Qianxia Zhang et al.   IMMUNITY

Neuropilin-1 modulates interferon-γ-stimulated signaling in brain microvascular endothelial cells

(2016) Ying Wang et al.   JOURNAL OF CELL SCIENCE

A Comparison Study of iTEP Nanoparticle-Based CTL Vaccine Carriers Revealed a Surprise Relationship between the Stability and Efficiency of the Carriers

(2016) Shuyun Dong et al.   Theranostics

Chemical Conjugation of Evans Blue Derivative: A Strategy to Develop Long-Acting Therapeutics through Albumin Binding

(2016) Haojun Chen et al.   Theranostics

New Life for Immunotoxin Cancer Therapy

(2015) R. Hassan et al.   CLINICAL CANCER RESEARCH

Response to Comment on Hughes et al. An Early Pregnancy HbA1c≥5.9% (41 mmol/mol) Is Optimal for Detecting Diabetes and Identifies Women at Increased Risk of Adverse Pregnancy Outcomes. Diabetes Care 2014;37:2953–2959

(2015) Ruth C.E. Hughes et al.   DIABETES CARE

Disease-modifying treatments for multiple sclerosis - a review of approved medications

(2015) Ø. Torkildsen et al.   EUROPEAN JOURNAL OF NEUROLOGY

Anti-CD20 Antibody Therapy and Susceptibility to Pneumocystis Pneumonia

(2015) Waleed Elsegeiny et al.   INFECTION AND IMMUNITY

An improved recombinant Fab-immunotoxin targeting CD22 expressing malignancies

(2014) Tapan K. Bera et al.   LEUKEMIA RESEARCH

Multiple Sclerosis: Current and Emerging Disease-Modifying Therapies and Treatment Strategies

(2014) Dean M. Wingerchuk et al.   MAYO CLINIC PROCEEDINGS

Novel Exenatide Analogs with Peptidic Albumin Binding Domains: Potent Anti-Diabetic Agents with Extended Duration of Action

(2014) Odile E. Levy et al.   PLoS One

In Vivo-Generated Antigen-Specific Regulatory T Cells Treat Autoimmunity Without Compromising Antibacterial Immune Response

(2014) S. Kasagi et al.   Science Translational Medicine

Using EAE to better understand principles of immune function and autoimmune pathology

(2013) Manu Rangachari et al.   JOURNAL OF AUTOIMMUNITY

Immune status following alemtuzumab treatment in human CD52 transgenic mice

(2013) Michael J. Turner et al.   JOURNAL OF NEUROIMMUNOLOGY

Type 1 diabetes

(2013) Mark A Atkinson et al.   LANCET

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

(2013) Taku Okazaki et al.   NATURE IMMUNOLOGY

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Immune checkpoints in central nervous system autoimmunity

(2012) Nicole Joller et al.   IMMUNOLOGICAL REVIEWS

A Recombinant Immunotoxin against the Tumor-Associated Antigen Mesothelin Reengineered for High Activity, Low Off-Target Toxicity, and Reduced Antigenicity

(2012) J. E. Weldon et al.   MOLECULAR CANCER THERAPEUTICS

Detection of autoreactive CD4 T cells using major histocompatibility complex class II dextramers

(2011) Chandirasegaran Massilamany et al.   BMC IMMUNOLOGY

Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies

(2011) Tom L. Van Belle et al.   PHYSIOLOGICAL REVIEWS

Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes

(2011) M. Onda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Belimumab in systemic lupus erythematosus: an update for clinicians

(2011) Susan S. Kim et al.   Therapeutic Advances in Chronic Disease

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

(2010) Yong Zhang et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

Genetics, pathogenesis and clinical interventions in type 1 diabetes

(2010) Jeffrey A. Bluestone et al.   NATURE

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

(2009) Brian T Fife et al.   NATURE IMMUNOLOGY

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

PD-1 ligands expressed on myeloid-derived APC in the CNS regulate T-cell responses in EAE

(2008) Bettina Schreiner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Engineering of a femtomolar affinity binding protein to human serum albumin

(2008) A. Jonsson et al.   PROTEIN ENGINEERING DESIGN & SELECTION