Maintaining mitochondria in beige adipose tissue

Increasing autophagy and blocking Nrf2 suppress laminopathy-induced age-dependent cardiac dysfunction and shortened lifespan

(2018) Shruti Bhide et al.   AGING CELL

Proteome Imbalance of Mitochondrial Electron Transport Chain in Brown Adipocytes Leads to Metabolic Benefits

(2018) Ruchi Masand et al.   Cell Metabolism

Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis

(2018) Yutaka Hasegawa et al.   Cell Metabolism

Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion

(2018) Ilan Y. Benador et al.   Cell Metabolism

Recent advances in the detection of brown adipose tissue in adult humans: a review

(2018) Frank J. Ong et al.   CLINICAL SCIENCE

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Wnt6 maintains anterior escort cells as an integral component of the germline stem cell niche

(2018) Xiaoxi Wang et al.   DEVELOPMENT

Exercise-induced ‘browning’ of adipose tissues

(2018) Peter Aldiss et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions

(2018) Pei-I Tsai et al.   MOLECULAR CELL

Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism

(2018) Xiaodan Lu et al.   Science Signaling

The Common and Distinct Features of Brown and Beige Adipocytes

(2018) Kenji Ikeda et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A map of the PGC-1α- and NT-PGC-1α-regulated transcriptional network in brown adipose tissue

(2018) Ji Suk Chang et al.   Scientific Reports

Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism

(2018) Xiaodan Lu et al.   Science Signaling

Adipose tissue autophagy related gene expression is associated with glucometabolic status in human obesity

(2018) Qing Xu et al.   Adipocyte

LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance

(2018) Larissa D. Cunha et al.   CELL

Thermal stress induces glycolytic beige fat formation via a myogenic state

(2018) Yong Chen et al.   NATURE

Drosophila MIC60/mitofilin conducts dual roles in mitochondrial motility and crista structure

(2017) Pei-I Tsai et al.   MOLECULAR BIOLOGY OF THE CELL

UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis

(2017) Kenji Ikeda et al.   NATURE MEDICINE

A fluorescence-based imaging method to measure in vitro and in vivo mitophagy using mt-Keima

(2017) Nuo Sun et al.   Nature Protocols

Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells

(2017) Min-Chieh Hsin et al.   Cell Death & Disease

A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B

(2017) N. Pengo et al.   Nature Communications

Cold-Inducible SIRT6 Regulates Thermogenesis of Brown and Beige Fat

(2017) Lu Yao et al.   Cell Reports

Muscle-Adipose Tissue Cross Talk

(2017) Kristin I. Stanford et al.   Cold Spring Harbor Perspectives in Medicine

Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1

(2017) Yinliang Zhang et al.   Molecular Metabolism

Functional Mitochondria in Health and Disease

(2017) Patries M. Herst et al.   Frontiers in Endocrinology

Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance

(2016) Svetlana Altshuler-Keylin et al.   Cell Metabolism

PKA Regulates PINK1 Stability and Parkin Recruitment to Damaged Mitochondria through Phosphorylation of MIC60

(2016) Shiori Akabane et al.   MOLECULAR CELL

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

(2016) Edward T. Chouchani et al.   NATURE

Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function

(2016) Daniel C. Berry et al.   Nature Communications

EBF2 promotes the recruitment of beige adipocytes in white adipose tissue

(2016) Rachel R. Stine et al.   Molecular Metabolism

Loss of Atg16 delays the alcohol-induced sedation response via regulation of Corazonin neuropeptide production in Drosophila

(2016) Kata Varga et al.   Scientific Reports

SMAD3 Negatively Regulates Serum Irisin and Skeletal Muscle FNDC5 and Peroxisome Proliferator-activated Receptor γ Coactivator 1-α (PGC-1α) during Exercise

(2015) Joseph P. Tiano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Measuring In Vivo Mitophagy

(2015) Nuo Sun et al.   MOLECULAR CELL

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

(2015) Jacqueline M. Kimmey et al.   NATURE

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

ATG12–ATG3 interacts with Alix to promote basal autophagic flux and late endosome function

(2015) Lyndsay Murrow et al.   NATURE CELL BIOLOGY

Genetic and functional characterization of clonally derived adult human brown adipocytes

(2015) Kosaku Shinoda et al.   NATURE MEDICINE

Exercise improves adipose function and inflammation and ameliorates fatty liver disease in obese diabetic mice

(2015) Fahrettin Haczeyni et al.   Obesity

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex

(2013) Haruya Ohno et al.   NATURE

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

(2013) Samuel A. Hasson et al.   NATURE

The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo

(2013) E. S. Vincow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis

(2013) Shu-Wen Qian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors

(2012) Joan Sanchez-Gurmaches et al.   Cell Metabolism

In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

(2012) Yun-Hee Lee et al.   Cell Metabolism

Resistance to Obesity by Repression ofVEGFGene Expression through Induction of Brown-Like Adipocyte Differentiation

(2012) Xiaodan Lu et al.   ENDOCRINOLOGY

Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin

(2010) E. Ziviani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat

(2010) T. J. Schulz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex

(2009) Shingo Kajimura et al.   NATURE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Arylsulfatase G, a Novel Lysosomal Sulfatase

(2008) Marc-André Frese et al.   JOURNAL OF BIOLOGICAL CHEMISTRY