Article
Materials Science, Multidisciplinary
Bita Derakhshani, Nader Parvin, Mohammad Khodaei
Summary: This study investigated the effects of sintering temperature on the mechanical behavior and biocompatibility of Ti/HA FGMs produced via SPS. The results showed that raising the sintering temperature to 1150℃ resulted in the formation of TiO2 and TCP phases, reducing compressive strength and increasing hardness. Moreover, increasing the sintering temperature to 1150℃ enhanced the biocompatibility of the fabricated Ti/HA FGMs.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Pharmacology & Pharmacy
Isha Mutreja, Caixia Lan, Qishun Li, Conrado Aparicio
Summary: Developing antimicrobial surfaces, including antimicrobial peptide coatings, is a promising approach to overcome dental implant-associated infection. This study presents a fast and efficient chemoselective conjugation technique to coat titanium implant surfaces with antimicrobial peptides. The evaluated surfaces showed antibacterial potency against primary colonizers and pathogens of dental surfaces, as well as demonstrated long-term viability of human dental pulp stem cells.
Article
Biochemistry & Molecular Biology
Sanako Makishi, Taisuke Watanabe, Kotaro Saito, Hayato Ohshima
Summary: This study aimed to analyze the effects of HA/beta-TCP on osseointegration at the bone-implant interface after immediately placed implants in the maxillae of 4-week-old mice. The lack of HA/beta-TCP on the implant surface affects the OPN immunoreactivity at the bone-implant interface and the rate of direct osteogenesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Materials Science, Multidisciplinary
Wei Xu, Aihua Yu, Yu Jiang, Yageng Li, Ce Zhang, Harsh-preet Singh, Bowen Liu, Chenjin Hou, Yun Zhang, Shiwei Tian, Jiazhen Zhang, Xin Lu
Summary: Functionally graded porous titanium scaffolds were designed and fabricated, showing high biocompatibility and mechanical properties, making them suitable for dental implants.
MATERIALS & DESIGN
(2022)
Article
Materials Science, Multidisciplinary
Agata Sotniczuk, Halina Garbacz
Summary: This article summarizes several strategies proposed in recent years to optimize the properties of nanostructured titanium products for dental applications, including bulk modifications, surface modifications, and deposition of bioactive coatings. Additionally, insights are provided on how changes in microstructure induced by the fabrication of nanograined Ti can be successfully exploited to improve surface properties.
ADVANCED ENGINEERING MATERIALS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Andres Stricker, Thomas Bergfeldt, Tobias Fretwurst, Owen Addison, Rainer Schmelzeisen, Rene Rothweiler, Katja Nelson, Christian Gross
Summary: The study found exogenous metal contaminants and other impurities in commercial titanium dental implants, which may provoke immunological reactions despite conforming to standard compositions. Further investigation into the clinical relevance of these findings and discussion on the adjustment of industry standards are warranted.
Article
Biotechnology & Applied Microbiology
Ruiying Li, Shuigen Li, Yi Zhang, Di Jin, Zhiming Lin, Xian Tao, Tianlai Chen, Liyuan Zheng, Zhisheng Zhang, Qianju Wu
Summary: In order to address the issues of insufficient osseointegration and implant-associated infections in Ti-based implants, scientists have developed a new biomimetic micro/nanoscale topography coating combined with antibacterial copper. This coating promotes cellular adhesion, spreading, and proliferation, while also reducing the viability of oral pathogens. These findings have valuable implications for orthopedic and dental implant applications.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Mahmoud Agour, Abdalla Abdal-hay, Mohamed K. Hassan, Michal Bartnikowski, Saso Ivanovski
Summary: The aim of this study was to form a functional layer on titanium implants to enhance bioactivity. Layers of polyurethane containing hydroxyapatite nanoparticles and magnesium particles were deposited on alkali-treated Ti surfaces. The results showed enhanced interfacial bonding and cell response to the coated Ti substrates, suggesting potential for inducing bone formation.
Article
Materials Science, Coatings & Films
Ana Barbara Batista, Michael Stanley, Ana Carolina Ferreira de Brito, Rebecca Vasconcellos, Michele Munk, Mario Jose-Bueno, Cristina Godoy, Erika Costa de Alvarenga, Claudia Karina Barbosa de Vasconcelos, Ariete Righi, Edesia M. B. de Sousa, Alan Barros de Oliveira, Ronaldo Junio Campos Batista, Jaqueline dos Santos Soares, Bernardo Ruegger Almeida Neves, Ana Paula Moreira Barbosa, Taise Matte Manhabosco
Summary: Nano-talc was successfully incorporated in the hydroxyapatite matrix through an eco-friendly liquid-phase exfoliation process, and it significantly improves the performance of bioceramic materials, including higher stiffness, reduced friction coefficient and wear damage, as well as corrosion resistance and biocompatibility.
SURFACE & COATINGS TECHNOLOGY
(2022)
Article
Chemistry, Physical
Frank A. Spitznagel, Estevam A. Bonfante, Tiago M. B. Campos, Maximilian A. Vollmer, Johannes Boldt, Sam Doerken, Petra C. Gierthmuehlen
Summary: The study evaluated the failure-load and survival-rate of screw-retained monolithic and bi-layered crowns bonded to titanium-bases before and after mouth-motion fatigue. It was found that porcelain-fused-to-zirconia crowns showed higher failure rate under fatigue compared to monolithic LDS crowns, indicating the latter's higher reliability as an all-ceramic material for screw-retained posterior hybrid-abutment-crowns.
Article
Chemistry, Physical
Lorena Kostelac, Luca Pezzato, Alessio Giorgio Settimi, Mattia Franceschi, Claudio Gennari, Katya Brunelli, Chiara Rampazzo, Manuele Dabala
Summary: In this study, bioactive coatings were produced on grade 2 titanium alloy using plasma electrolytic oxidation (PEO) process. The effects of KOH addition to electrolyte and working in direct or pulsed current mode were investigated. The coatings exhibited improved corrosion resistance and cell adhesion compared to the untreated sample.
SURFACES AND INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Eren Yilmaz, Fatih Caliskan
Summary: The study designed a functionally graded dental implant sample using different materials at the interface of different tissues and bones to improve biocompatibility and durability. This new type of dental implant shows promising results in terms of withstanding chewing forces and antibacterial properties.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Multidisciplinary Sciences
Yomna H. Shash, Mohamed T. El-Wakad, Mohamed A. A. El-Dosoky, Mohamed M. Dohiem
Summary: Fixed prostheses are common treatment options for edentulous patients, but researchers are exploring alternative materials due to limitations of titanium. This study used finite element analysis to evaluate the stress distribution in fixed prostheses with polymeric frameworks and different bone densities. The choice of framework material depended on spongy bone density. Soft frameworks were recommended for low-density cases to reduce stresses on bone tissues.
SCIENTIFIC REPORTS
(2023)
Article
Materials Science, Coatings & Films
Maria Helena R. Borges, Hemalatha Kanniyappan, Yani Sun, Bruna Egumi Nagay, Nilson C. da Cruz, Mathew T. Mathew, Valentim A. R. Barao
Summary: Polypyrrole (PPy) films electrodeposited on plasma electrolytic oxidation (PEO) surfaces exhibit excellent mechanical and electrochemical performance, making them promising for implant applications. This study investigates the tribocorrosion behavior of PEO-treated surfaces coated with PPy films with and without zinc (Zn), as well as the effect of PPy films on human osteoblast-like cells. The results show that PPy films improve tribocorrosion performance and the PPy/Zn-coated surface is cytocompatible, enhancing cell adhesion and proliferation.
SURFACE & COATINGS TECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Anderson Wagner Alves de Menezes, Ivan Alves de Souza, Thercio Henrique de Carvalho Costa, Tharsia Cristiany de Carvalho Costa, Romulo Ribeiro Magalhaes de Sousa, Rubens Maribondo Nascimento, Michelle de Medeiros Aires, Michelle Cequeira Feitor
Summary: The tissue-prosthesis relationship is crucial for the success of an implant, and efforts have been made to improve the affinity between the implant and the human body. This study successfully produced a hydroxyapatite coating on metallic surfaces using plasma electrolytic oxidation, and investigated the effects of treatment time, current behavior, and polarity on the coating formation.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Chemistry, Physical
Saeed Askari, Mohammad Mehdi Khodaei, Mohammad Jafarzadeh
Summary: This study reports the preparation and application of UiO-66-NH2-bis(aminomethyl)-phosphinic acid, which is designed via a multi-step post-synthesis modification of a Zr-based MOF, UiO-66-NH2. The modified MOF serves as a multifunctional heterogeneous catalyst in the multicomponent reaction of Hantzsch, showing a synergistic effect between the phosphinic acid and the support. The catalyst can be easily recycled and successfully reused multiple times.
Article
Engineering, Biomedical
Milad Mansouri Boroujeni, Seyed Mahmoud Barzi, Mahdi Zafari, Mohsen Chiani, Mojtaba Chehrazi, Hamed Nosrati, Mohammad Sadegh Shams Nosrati, Sara Nayyeri, Mohammad Khodaei, Shahin Bonakdar, Morvarid Shafiei
Summary: In this study, cefazolin-loaded niosomes were electrosprayed onto chitosan membrane for wound healing applications. In vitro and in vivo studies showed that the membrane had antibacterial properties and could enhance skin regeneration, suggesting its promising role in the treatment of chronic wounds and bacterial infections.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2022)
Article
Engineering, Multidisciplinary
Mojtaba Momeni, Kamran Amini, Ali Heidari, Mohammad Khodaei
Summary: In this study, nano-biocomposites of polycaprolactone (PCL) and nanofluorapatite (nFA) were prepared and used for 3D printing scaffold fabrication. The analysis results confirmed the even distribution of nFA particles in the PCL matrix without chemical interaction. The addition of nFA improved the thermal and mechanical properties of the composites, with the best performance achieved in the PCL/20nFA composite.
JOURNAL OF BIONIC ENGINEERING
(2022)
Article
Materials Science, Multidisciplinary
Sayed Hossein Mirdamadi, Mohammad Khodaei, Alireza Valanezhad, Ikuya Watanabe, Farahnaz Nejatidanesh, Omid Savabi
Summary: Different heat treatment temperatures were applied to titanium implants after surface modification using chemical treatment with hydrogen peroxide. XRD analysis showed that the main phase on the surface of heat-treated samples below 650 ? was anatase. Raman spectroscopy confirmed the presence of anatase as the dominant phase along the Raman shift with noticeable peak intensity. FESEM observation indicated that the porous structures did not significantly change in morphology with increasing temperature. Contact angle and ellipsometry measurements were used to determine the hydrophobicity and optical properties of the oxide surface, respectively.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Engineering, Biomedical
Sharareh Ghaziof, Shahrokh Shojaei, Mehdi Mehdikhani, Mohammad Khodaei, Milad Jafari Nodoushan
Summary: The human heart cannot regenerate itself after a wound, leading to damage and scar formation in myocardial tissue. To address this issue, scientists have proposed using 3D printing to create scaffolds with suitable properties. In this study, Poly epsilon-caprolactone (PCL)/Gold nanoparticles (GNPs) nanocomposite scaffolds were prepared using Fused Deposition Modeling (FDM) and characterized using various techniques. The results show that the scaffold containing 0.5 wt% GNPs exhibits optimal properties for cardiovascular applications.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Chemistry, Physical
Marzieh Rabiei, Motahareh Sadat Raziyan, Reza Ebrahimi-Kahrizsangi, Sohrab Nasiri, Arvydas Palevicius, Giedrius Janusas, Andrius Vilkauskas
Summary: Mg-based alloys have suitable properties for biomaterials, but they lack antibacterial properties and have low mechanical strength. In this study, a new combination of Ag/Zn/Mg was prepared to enhance bioactivity. The use of different polymers, including PolyCaproLactone, PolyHydroxyButyrate, and PolyVinylTriMethoxySilane, was also investigated. Experimental results showed that the best performance was achieved when PolyHydroxyButyrate was used.
Article
Materials Science, Multidisciplinary
Mohammad Khodaei, Farahnaz Nejatidanesh, Lobat Tayebi, Omid Savabi
Summary: In this study, lithium silicate glass frits with different SiO2/Li2O ratios were prepared by the melting method. The resulting glass frits were then hot-pressed at different temperatures to obtain lithium metasilicate glass ceramics (LMSGC). It was found that the wettability, hardness, and cell viability of LMSGC can be tuned by changing the SiO2/Li2O ratio, which is of great importance for dental applications.
MATERIALS TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Saeed Askari, Mohammad Mehdi Khodaei, Mohammad Jafarzadeh, Abdolhamid Mikaeili
Summary: In this study, a porous heterogeneous catalyst was prepared via green deposition of silver nanoparticles on the surface of a functionalized metal-organic framework. The catalyst showed effective catalytic activity for the reduction of 4-nitrophenol and cyanation of aryl halides, as well as prominent antibacterial activity against Staphylococcus aureus and Escherichia coli.
PROCESS BIOCHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Mohsen Karegar, Mohammad Mehdi Khodaei
Summary: In this study, a reusable magnetic catalyst was synthesized by immobilizing sulfonic acid on polythiophene-layered magnetite. The catalyst exhibited high catalytic efficiency for the green synthesis of compounds. Characterization techniques confirmed the successful attachment of the sulfonic group on the catalyst's surface. The increased number of acidic groups on the catalyst's surface led to enhanced yield, and the catalyst showed excellent stability and reusability.
Article
Chemistry, Physical
Nasim Batooie, Mohammad Mehdi Khodaei, Kiumars Bahrami, Seyyed Shahram Miraghaee, Nouraddin Hosseinzadeh, Soraya Sajadimajd
Summary: An efficient and environmentally friendly method using hexyltriphenylphosphonium bromide ionic liquid as a promoter and solvent has been developed for the synthesis of novel compounds. The method allows for the one-pot synthesis of the target products from CH acids, aldehydes, and 2-mercaptobenzimidazole at ambient temperature, with high yields and short reaction times. Furthermore, the synthesized compounds exhibit significant anti-cancer effects on skin, prostate, and pancreatic cancers.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Zahra Karami, Mohammad Mehdi Khodaei
Summary: A new metal-organic framework catalyst, UiO-66-N=CH-C6H3PO4H, was studied, which showed hydrogen phosphate groups as the main active catalytic sites on its surface. The catalyst exhibited durability and robustness in acid-catalyzed syntheses, making it a promising candidate for catalytic applications.
RESEARCH ON CHEMICAL INTERMEDIATES
(2023)
Article
Chemistry, Analytical
Sohrab Nasiri, Marzieh Rabiei, Ieva Markuniene, Mozhgan Hosseinnezhad, Reza Ebrahimi-Kahrizsangi, Arvydas Palevicius, Andrius Vilkauskas, Giedrius Janusas
Summary: A novel nanocrystalline composite material for gas/temperature sensing is proposed in this study. It addresses the sensitivity issue of the material to high temperatures by designing and fabricating a freeze-drying machine to prevent structural damage. Various analyses and experiments were conducted to investigate the influence of different environments on the composite material. The results indicate that the composite material exhibits good selectivity to oxygen, vaporized ethanol, N-2, and CO environments.
Article
Biochemistry & Molecular Biology
Mohammad Saeid Rostami, Mohammad Mehdi Khodaei
Summary: Regarding the existence of cationic and anionic dyes in water, it is crucial to develop new techniques for their simultaneous removal. In this study, a chitosan/poly-2-aminothiazole composite film reinforced with multi-walled carbon nanotube-Mg Al-layered double hydroxide (CPML) was created and used as an effective adsorbent for methylene blue (MB) and methyl orange (MO) dyes removal. The synthesized CPML was characterized using SEM, TGA, FTIR, XRD, and BET methods. The highest adsorption capacities were found to be 471.12 and 230.87 mg g-1 for MB and MO, respectively. Different isotherm and kinetic models showed that the adsorption of dyes onto CPML nanocomposite (NC) followed the Langmuir and pseudo-second-order kinetic model, indicating monolayer adsorption on the homogeneous surface of NCs. The reusability experiment demonstrated that the CPML NC could be used multiple times. Experimental results suggest that the CPML NC has significant potential for treating cationic and anionic dye-contaminated water.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Pharmacology & Pharmacy
Hamed Nosrati, Morteza Heydari, Zahra Tootiaei, Saeid Ganjbar, Mohammad Khodaei
Summary: Skin serves as the primary barrier against pathogenic microorganisms and any significant damage to the skin can lead to bacterial invasion and wound infection. Effective wound management is crucial to prevent complications like tissue necrosis or sepsis, which can be life-threatening. Polysaccharide-based scaffolds containing antibacterial nanobiomaterials have gained interest for their immunological safety and ability to enhance wound healing by reducing bacterial colonization and infection. This review focuses on the delivery of antibacterial agents and nanobiomaterials via polysaccharide-based scaffolds for wound healing applications.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Bita Derakhshani, Nader Parvin, Mohammad Khodaei
Summary: This study investigated the effects of sintering temperature on the mechanical behavior and biocompatibility of Ti/HA FGMs produced via SPS. The results showed that raising the sintering temperature to 1150℃ resulted in the formation of TiO2 and TCP phases, reducing compressive strength and increasing hardness. Moreover, increasing the sintering temperature to 1150℃ enhanced the biocompatibility of the fabricated Ti/HA FGMs.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
