Article
Nutrition & Dietetics
Katarzyna Domaszewska, Sara Gorna, Malwina Pietrzak, Tomasz Podgorski
Summary: Endurance training in the extended pulmonary rehabilitation program for COPD patients does not exacerbate oxidative stress and blood total phenolics concentration.
Article
Biochemistry & Molecular Biology
Mohammad Haki, Amir Shamloo, Sara-Sadat Eslami, Fatemeh Mir-Mohammad-Sadeghi, Sasan Maleki, Arman Hajizadeh
Summary: The field of tissue engineering aims to overcome the limitations of traditional tissue replacements, and a recent study introduces a chitosan-coated porous skin scaffold based on sodium carboxymethyl cellulose (NaCMC) and sodium alginate (SA) hydrogels. The study found that adding a chitosan coating and allantoin significantly improved the antibacterial properties and cell viability of the scaffolds. Additionally, the composition ratio and cross-linking agent concentration also influenced the performance of the scaffolds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Agriculture, Dairy & Animal Science
Yajing Ban, Le Luo Guan
Summary: DFMs, as feed additives, are considered as alternatives to antibiotics in the livestock industry. They have been mainly utilized to improve feed efficiency and ruminant productivity, but their effects and modes of action on young ruminants still need further investigation.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Agronomy
Kumiko Ochiai, Yosuke Nomura, Asuka Uesugi, Toru Matoh
Summary: This study investigates the accumulation of biuret and changes in metabolites in rice plants under biuret toxicity. Transgenic rice plants overexpressing bacterial biuret hydrolase were found to have improved biuret tolerance. The results suggest that rice plants subjected to biuret toxicity need to reduce the concentration of surplus ammonium ions via synthesizing nitrogen-rich compounds.
Article
Environmental Sciences
Slawomir Dresler, Robert Zubel, Izabela Baczewska, Michal Karakula, Jan Sawicki, Agnieszka Hanaka, Sylwia Zieliinska, Bartosz J. Plachano, Ireneusz Sowa, Magdalena Wojciak, Maciej Strzemski
Summary: The study examined the accumulation of allantoin and trace metals in nine moss species under stress conditions. Both environmental anthropopressure effect and laboratory-simulated stress conditions were monitored. Different moss samples from non-TM contaminated area, urban area, and metalliferous area were collected and tested for their allantoin content in response to Cd, Pb, Hg, Ni, Zn, salinity, and an acidic environment. The results showed that there were large differences in the metal and allantoin accumulation capability of mosses from different locations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Multidisciplinary Sciences
Nazli Deger, Xuemei Cao, Christopher P. Selby, Saygin Gulec, Hiroaki Kawara, Evan B. Dewey, Li Wang, Yanyan Yang, Sierra Archibald, Berkay Selcuk, Ogun Adebali, Jeff Sekelsky, Aziz Sancar, Zhenxing Liu
Summary: This study reveals the transcription-coupled repair (TCR) ability in Drosophila comparable to human cells, and identifies XPC repair factor as a crucial component for both global and transcription-coupled repair in Drosophila.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Biochemistry & Molecular Biology
Ping Zhang, Yanjie Wang, Jingyu Zhang, Tie Hong
Summary: This study investigates the anti-pseudoallergy effect of allantoin (AT) and its underlying mechanism. The results demonstrate that AT can inhibit degranulation and improve pathological changes induced by Compound 48/80. Additionally, AT helps restore body temperature decrease caused by Compound 48/80.
Review
Biochemistry & Molecular Biology
Arrigo F. G. Cicero, Federica Fogacci, Valentina Di Micoli, Cristina Angeloni, Marina Giovannini, Claudio Borghi
Summary: Purines, such as adenine and guanine, have various important roles in cells, including being found in nucleic acids, serving as structural components of coenzymes, and playing crucial roles in energy metabolism and signal transduction. They also contribute significantly to the physiology of platelets, muscles, and neurotransmission. Maintaining a balanced purine ratio is essential for cell growth, proliferation, and survival. Dysfunctions in purine metabolism, such as hyperuricemia, have been associated with certain human diseases, particularly cardiovascular ones. Investigating purine metabolism dysfunctions, the functionality of xanthine oxidoreductase, and the formation of catabolites in urine and saliva can provide insights and potential markers for oxidative stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Jinseok Kim, Chia-Lung Li, Xuemin Chen, Yanxiang Cui, Filip M. Golebiowski, Huaibin Wang, Fumio Hanaoka, Kaoru Sugasawa, Wei Yang
Summary: Nucleotide excision repair is responsible for removing DNA lesions caused by ultraviolet light, cisplatin-like compounds, and bulky adducts. This study reveals the structures of human XPC recognizing DNA lesions and transferring them to the TFIIH core complex for verification and further repair.
Article
Environmental Sciences
Hong-Jie Zhang, Hao-Ran Zhou, Wei Pan, Chuan Wang, Yue-Yue Liu, Liuyan Yang, Martin Tsz-Ki Tsui, Ai-Jun Miao
Summary: In this study, a label-free technique called hyperspectral imaging with enhanced dark-field microscopy (HSI-DFM) was used to visualize and quantify the bioaccumulation of nanoparticles (NPs) in human cells. The technique was optimized to accurately identify intracellular NPs, and its accuracy was evaluated by comparing the results with fluorescence microscopy and flow cytometry. HSI-DFM was found to be a useful tool for studying the accumulation and distribution of NPs in different cell lines and with varying chemical compositions.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Juan Wang, Yingbo Li, Yinxiao Wang, Fengping Du, Yue Zhang, Ming Yin, Xiuqin Zhao, Jianlong Xu, Yongqing Yang, Wensheng Wang, Binying Fu
Summary: In this study, the effects of exogenous allantoin on salt-stressed rice seedlings were comprehensively analyzed. The results showed that allantoin positively affects salt tolerance by increasing endogenous allantoin levels, enhancing antioxidant activities, and maintaining sodium and potassium homeostasis. Transcriptome analysis revealed upregulated genes involved in ion transport and redox regulation, as well as downregulated genes related to transcription and post-transcriptional regulation, carbohydrate metabolism, chromosome remodeling, and cell wall organization. Metabolite analysis detected the accumulation of metabolites with antioxidant activities and intermediate products of the allantoin biosynthetic pathway, suggesting that allantoin enhances salt tolerance by inducing ROS scavenging cascades.
Article
Pharmacology & Pharmacy
Laura Tamayo, Paula Santana, Juan C. Forero, Matias Leal, Nicolas Gonzalez, Mauricio Diaz, Nicolas Guiliani, Eugenio Hamm, Marcela Urzua
Summary: The prevalence of chronic and acute wounds presents a challenge for health systems globally. A new study has developed a wound dressing material that releases active agents to prevent infection and promote healing. The material effectively inhibits bacterial growth and promotes fibroblast cell proliferation, making it suitable for non-adherent wound dressings.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Biochemistry & Molecular Biology
Rosa Alicia Saucedo-Acuna, Karen Zulema Meza-Valle, Juan Carlos Cuevas-Gonzalez, Elsa Gabriela Ordonez-Casanova, Manuel Ivan Castellanos-Garcia, Erasto Armando Zaragoza-Contreras, Genaro Federico Tamayo-Perez
Summary: This study presents a liquid allantoin-enriched pectin hydrogel with hydrophilic behavior for wound healing. The hydrogel exhibits hydrophilic properties and contains functional groups related to healing efficacy. Experimental results show that the hydrogel promotes wound drying and improves interaction between the hydrogel and cells, leading to reduced healing time and complete wound closure in 15 days.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Plant Sciences
Marco Antonio Bosse, Mariana Bocchi da Silva, Natalia Gabriela Ros Marques de Oliveira, Maycon Anderson de Araujo, Cleverson Rodrigues, Jaquelyne Poliszuk de Azevedo, Andre Rodrigues dos Reis
Summary: Legume plants from the Fabaceae family have the ability to fix atmospheric nitrogen into ammonia through a symbiotic relationship with rhizobia bacteria. Flavonoids, especially isoflavonoids, induce nod genes in rhizobia bacteria and play a crucial role in nodulation and ureide production. Ureides are the main nitrogen transport form in tropical legumes, catabolized in leaves to produce amino acids and proteins essential for plant growth and yield.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Review
Biotechnology & Applied Microbiology
Abir Zebian, Maya El-Dor, Abdullah Shaito, Frederic Mazurier, Hamid Reza Rezvani, Kazem Zibara
Summary: XPC plays a crucial role in DNA damage recognition and repair, as well as DNA damage response and cell fate decisions. Its interactions with other proteins can influence cell apoptosis, senescence, or tumorigenesis. Understanding the status of XPC is important for successful cancer treatment and patient survival.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
(2022)
Article
Agriculture, Dairy & Animal Science
Telisson Ribeiro Goncalves, Jose Renaldo Vilar da Silva Filho, Gilmar Amaro Pereira, Tarcisio Martins Meira, Moema Kelly Nogueira de Sa, Glayciane Costa Gois, Crislane de Souza Silva, Fleming Sena Campos, Sandra Mari Yamamoto, Gherman Garcia Leal de Araujo
Summary: This study evaluated the effects of diets containing vitiviniculture waste on intake, digestibility, water balance, nitrogen balance, ingestive behavior, performance, and carcass traits of lambs. The results showed that feeding lambs with diets containing 216 g/kg cactus pear and 144 g/kg vitiviniculture waste resulted in higher intake and digestibility.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2024)
Article
Agriculture, Dairy & Animal Science
Q. Zhang, C. L. Walk, A. J. Cowieson, K. Stamatopoulos, J. L. Wu, J. O. B. Sorbara
Summary: This study evaluated the efficacy of a novel phytase in terms of phytate hydrolysis and the digestibility of phosphorus and calcium in broiler chickens fed low and high phytate diets. The results showed that the phytase effectively hydrolyzed phytate and increased digestible phosphorus and calcium. The response to dietary phytate varied in terms of age and the specific nutrient being evaluated.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2024)
Article
Agriculture, Dairy & Animal Science
J. Song, D. M. Holanda, C. H. Heuer, C. M. Nyachoti
Summary: This study determined the energy contents of hybrid rye fed to growing pigs, and investigated the effects of particle size on energy values. Results showed that finely ground hybrid rye had higher digestible energy and metabolizable energy compared to coarsely ground hybrid rye, while net energy only showed a slight improvement.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2024)
Article
Agriculture, Dairy & Animal Science
Mohamed Salah Ayyat, Ahmed Mohamed Nabil Ayyat, Mohamed S. Abdel-Rahman, Adham A. Al-Sagheer
Summary: This study evaluated the impact of replacing fish meal with sugar beet and carrot leaf protein concentrate in Nile tilapia. The results showed that replacing 75% of fish meal with leaf protein concentrate had no adverse effects on growth and health, and it was more efficient in terms of economic benefits.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2024)