Dual-targeting by CRISPR/Cas9 leads to efficient point mutagenesis but only rare targeted deletions in the rice genome

High-efficiency genome editing using a dmc1 promoter-controlled CRISPR/Cas9 system in maize

(2018) Chao Feng et al.   PLANT BIOTECHNOLOGY JOURNAL

Optimized paired-sgRNA/Cas9 cloning and expression cassette triggers high-efficiency multiplex genome editing in kiwifruit

(2018) Zupeng Wang et al.   PLANT BIOTECHNOLOGY JOURNAL

CRISPR/Cas9 cleavages in budding yeast reveal templated insertions and strand-specific insertion/deletion profiles

(2018) Brenda R. Lemos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly efficient heritable targeted deletions of gene clusters and non-coding regulatory regions in Arabidopsis using CRISPR/Cas9

(2018) Julius Durr et al.   Scientific Reports

CRISPR/Cas9-mediated efficient targeted mutagenesis in grape in the first generation

(2017) Xianhang Wang et al.   PLANT BIOTECHNOLOGY JOURNAL

Coordinated Functional Divergence of Genes after Genome Duplication inArabidopsis thaliana

(2017) Riet De Smet et al.   PLANT CELL

Deletion of a target gene in Indica rice via CRISPR/Cas9

(2017) Ying Wang et al.   PLANT CELL REPORTS

Dual-targeting by CRISPR/Cas9 for precise excision of transgenes from rice genome

(2017) Vibha Srivastava et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Discovery of rice essential genes by characterizing a CRISPR-edited mutation of closely related rice MAP kinase genes

(2017) Bastian Minkenberg et al.   PLANT JOURNAL

Single-Step qPCR and dPCR Detection of Diverse CRISPR-Cas9 Gene Editing Events in Vivo

(2017) Micol Falabella et al.   G3-Genes Genomes Genetics

Heritable Genomic Fragment Deletions and Small Indels in the Putative ENGase Gene Induced by CRISPR/Cas9 in Barley

(2017) Eszter Kapusi et al.   Frontiers in Plant Science

The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair

(2016) Maria Jasin et al.   DNA REPAIR

DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks

(2016) Megan van Overbeek et al.   MOLECULAR CELL

ARGOS8 variants generated by CRISPR-Cas9 improve maize grain yield under field drought stress conditions

(2016) Jinrui Shi et al.   PLANT BIOTECHNOLOGY JOURNAL

Genetic chimerism of CRISPR/Cas9-mediated rice mutants

(2016) Geupil Jang et al.   Plant Biotechnology Reports

Efficient CRISPR/Cas9-based gene knockout in watermelon

(2016) Shouwei Tian et al.   PLANT CELL REPORTS

Generation of chromosomal deletions in dicotyledonous plants employing a user-friendly genome editing toolkit

(2016) Jana Ordon et al.   PLANT JOURNAL

CRISP-ID: decoding CRISPR mediated indels by Sanger sequencing

(2016) Jonas Dehairs et al.   Scientific Reports

Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites

(2015) Jeongbin Park et al.   BIOINFORMATICS

Targeted genome modifications in soybean with CRISPR/Cas9

(2015) Thomas B Jacobs et al.   BMC BIOTECHNOLOGY

Evolution of cis-regulatory elements and regulatory networks in duplicated genes of Arabidopsis thaliana

(2015) Andrej A Arsovski et al.   PLANT PHYSIOLOGY

Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system

(2015) Kabin Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The polyploidy revolution then...and now: Stebbins revisited

(2014) D. E. Soltis et al.   AMERICAN JOURNAL OF BOTANY

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

(2014) Samuel H. Sternberg et al.   NATURE

Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice

(2014) Huanbin Zhou et al.   NUCLEIC ACIDS RESEARCH

The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation

(2014) Hui Zhang et al.   PLANT BIOTECHNOLOGY JOURNAL

Efficient Gene Editing in Tomato in the First Generation Using the Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-Associated9 System

(2014) C. Brooks et al.   PLANT PHYSIOLOGY

Plant Genome Engineering with Sequence-Specific Nucleases

(2013) Daniel F. Voytas   Annual Review of Plant Biology

Application of the CRISPR–Cas System for Efficient Genome Engineering in Plants

(2013) Yanfei Mao et al.   Molecular Plant

RNA-Guided Genome Editing in Plants Using a CRISPR–Cas System

(2013) Kabin Xie et al.   Molecular Plant

Plant genome editing made easy: targeted mutagenesis in model and crop plants using the CRISPR/Cas system

(2013) Khaoula Belhaj et al.   Plant Methods

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Redundancy and rewiring of genetic networks following genome-wide duplication events

(2012) Riet De Smet et al.   CURRENT OPINION IN PLANT BIOLOGY

Marker-free site-specific gene integration in rice based on the use of two recombination systems

(2012) Soumen Nandy et al.   PLANT BIOTECHNOLOGY JOURNAL

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Organ and Cell Type–Specific Complementary Expression Patterns and Regulatory Neofunctionalization between Duplicated Genes in Arabidopsis thaliana

(2011) Shao-Lun Liu et al.   Genome Biology and Evolution

Repairing breaks in the plant genome: the importance of keeping it together

(2011) Wanda M. Waterworth et al.   NEW PHYTOLOGIST

Recombinase technology: applications and possibilities

(2010) Yueju Wang et al.   PLANT CELL REPORTS

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

(2010) B. D. Wallace et al.   SCIENCE

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

(2009) H. J. Kim et al.   GENOME RESEARCH

Short motif sequences determine the targets of the prokaryotic CRISPR defence system

(2009)   MICROBIOLOGY-SGM

Natural variation at the DEP1 locus enhances grain yield in rice

(2009) Xianzhong Huang et al.   NATURE GENETICS

Site-specific excisional recombination strategies for elimination of undesirable transgenes from crop plants

(2008) David Gidoni et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT