Ibogaine Administration Modifies GDNF and BDNF Expression in Brain Regions Involved in Mesocorticolimbic and Nigral Dopaminergic Circuits

Psychedelics Promote Structural and Functional Neural Plasticity

(2018) Calvin Ly et al.   Cell Reports

Ibogaine Acute Administration in Rats Promotes Wakefulness, Long-Lasting REM Sleep Suppression, and a Distinctive Motor Profile

(2018) Joaquín González et al.   Frontiers in Pharmacology

Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes

(2018) Deborah C. Mash et al.   Frontiers in Pharmacology

Pharmacochaperoning in aDrosophilamodel system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism

(2017) H. M. Mazhar Asjad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal plasticity and neurotrophic factors in drug responses

(2017) E Castrén et al.   MOLECULAR PSYCHIATRY

Update of neurotrophic factors in neurobiology of addiction and future directions

(2017) Maryna Koskela et al.   NEUROBIOLOGY OF DISEASE

Ibogaine treatment outcomes for opioid dependence from a twelve-month follow-up observational study

(2017) Geoffrey E. Noller et al.   AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE

Treatment of opioid use disorder with ibogaine: detoxification and drug use outcomes

(2017) Thomas Kingsley Brown et al.   AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE

Neuroprotective Effects of Antidepressants via Upregulation of Neurotrophic Factors in the MPTP Model of Parkinson’s Disease

(2016) Sina Shadfar et al.   MOLECULAR NEUROBIOLOGY

Region-specific expression of precursor and mature brain-derived neurotrophic factors after chronic alcohol exposure

(2016) Jin-Wei Yang et al.   AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE

Deconstructing the Iboga Alkaloid Skeleton: Potentiation of FGF2-induced Glial Cell Line-Derived Neurotrophic Factor Release by a Novel Compound

(2015) Madalee M. Gassaway et al.   ACS Chemical Biology

Coronaridine congeners inhibit human α3β4 nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites

(2015) Hugo R. Arias et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Anti-Addiction Drug Ibogaine and the Heart: A Delicate Relation

(2015) Xaver Koenig et al.   MOLECULES

Brain-derived neurotrophic factor: Regulation, effects, and potential clinical relevance

(2015) E. E. Benarroch   NEUROLOGY

Noribogaine is a G-protein biased κ-opioid receptor agonist

(2015) Emeline L. Maillet et al.   NEUROPHARMACOLOGY

Escalation of cocaine self-administration in adulthood after social defeat of adolescent rats: role of social experience and adaptive coping behavior

(2015) Andrew R. Burke et al.   PSYCHOPHARMACOLOGY

NCAM Signaling Mediates the Effects of GDNF on Chronic Morphine-Induced Neuroadaptations

(2014) Li Li et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Treating drug dependence with the aid of ibogaine: A retrospective study

(2014) Eduardo Ekman Schenberg et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Direct and indirect pathways of basal ganglia: a critical reappraisal

(2014) Paolo Calabresi et al.   NATURE NEUROSCIENCE

Anti-aggressive effect elicited by coca-paste in isolation-induced aggression of male rats: Influence of accumbal dopamine and cortical serotonin

(2013) María Noel Meikle et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effect of Iboga Alkaloids on µ-Opioid Receptor-Coupled G Protein Activation

(2013) Tamara Antonio et al.   PLoS One

The Mechanistic Basis for Noncompetitive Ibogaine Inhibition of Serotonin and Dopamine Transporters

(2012) Simon Bulling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Upregulation of Nerve Growth Factor in Central Amygdala Increases Sensitivity to Opioid Reward

(2012) Bihua Bie et al.   NEUROPSYCHOPHARMACOLOGY

ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA

(2012) Ying Sun et al.   PLoS One

Endogenous proBDNF is a negative regulator of migration of cerebellar granule cells in neonatal mice

(2011) Zhi-Qiang Xu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Antidepressants elevate GDNF expression and release from C6 glioma cells in a β-arrestin1-dependent, CREB interactive pathway

(2011) Moran Golan et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Neuronal Brain-derived Neurotrophic Factor Is Synthesized in Excess, with Levels Regulated by Sortilin-mediated Trafficking and Lysosomal Degradation

(2011) Sarah Felice Evans et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin reverses corticosterone-induced depressive-like behavior and decrease in brain BDNF levels in rats

(2011) Zhen Huang et al.   NEUROSCIENCE LETTERS

Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration

(2010) Sebastien Carnicella et al.   ADDICTION BIOLOGY

Interaction of ibogaine with human α3β4-nicotinic acetylcholine receptors in different conformational states

(2010) Hugo R. Arias et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

GDNF is an Endogenous Negative Regulator of Ethanol-Mediated Reward and of Ethanol Consumption After a Period of Abstinence

(2009) Sebastien Carnicella et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

Endogenous BDNF in the Dorsolateral Striatum Gates Alcohol Drinking

(2009) J. Jeanblanc et al.   JOURNAL OF NEUROSCIENCE

Global signatures of protein and mRNA expression levels

(2009) Raquel de Sousa Abreu et al.   Molecular BioSystems

Role of BDNF and GDNF in drug reward and relapse: A review

(2009) Udi E. Ghitza et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review

(2008) R Mačiulaitis et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Serotonin (5-HT) induces glial cell line-derived neurotrophic factor (GDNF) mRNA expression via the transactivation of fibroblast growth factor receptor 2 (FGFR2) in rat C6 glioma cells

(2008) Mami Tsuchioka et al.   JOURNAL OF NEUROCHEMISTRY

Differential Excitability and Modulation of Striatal Medium Spiny Neuron Dendrites

(2008) M. Day et al.   JOURNAL OF NEUROSCIENCE

Neurotrophic factors and structural plasticity in addiction

(2008) Scott J. Russo et al.   NEUROPHARMACOLOGY

GDNF — A potential target to treat addiction

(2008) Sebastien Carnicella et al.   PHARMACOLOGY & THERAPEUTICS

GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse

(2008) S. Carnicella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of accumbens BDNF and TrkB in cocaine-induced psychomotor sensitization, conditioned-place preference, and reinstatement in rats

(2008) Amine Bahi et al.   PSYCHOPHARMACOLOGY

Antidepressant drug treatments induce glial cell line-derived neurotrophic factor (GDNF) synthesis and release in rat C6 glioblastoma cells

(2003) Kazue Hisaoka et al.   JOURNAL OF NEUROCHEMISTRY