Exosomes mediate Zika virus transmission through SMPD3 neutral Sphingomyelinase in cortical neurons

Coordination of different ligands to copper(II) and cobalt(III) metal centers enhances Zika virus and dengue virus loads in both arthropod cells and human keratinocytes

(2018) Shovan Dutta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Arthropod EVs mediate dengue virus transmission through interaction with a tetraspanin domain containing glycoprotein Tsp29Fb

(2018) Ashish Vora et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells

(2018) Wenshuo Zhou et al.   PLoS Pathogens

Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869

(2018) Yunlong Huang et al.   Cell Discovery

The pathogenesis of microcephaly resulting from congenital infections: why is my baby’s head so small?

(2017) L. D. Frenkel et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

How does Zika virus cause microcephaly?

(2017) Zhexing Wen et al.   GENES & DEVELOPMENT

Zika Virus Targeting in the Developing Brain

(2017) Anthony N. van den Pol et al.   JOURNAL OF NEUROSCIENCE

Zika virus induces astrocyte differentiation in neural stem cells

(2017) Olivia V. Lossia et al.   JOURNAL OF NEUROVIROLOGY

Zika virus directly infects peripheral neurons and induces cell death

(2017) Yohan Oh et al.   NATURE NEUROSCIENCE

Stress-induced unfolded protein response contributes to Zika virus–associated microcephaly

(2017) Ivan Gladwyn-Ng et al.   NATURE NEUROSCIENCE

Zika virus dynamics: When does sexual transmission matter?

(2017) Ondrej Maxian et al.   Epidemics

A novel mechanism of antibody-mediated enhancement of flavivirus infection

(2017) Denise Haslwanter et al.   PLoS Pathogens

Advances in Developing Therapies to Combat Zika Virus: Current Knowledge and Future Perspectives

(2017) Ashok Munjal et al.   Frontiers in Microbiology

Zika virus genome biology and molecular pathogenesis

(2017) Anyou Wang et al.   Emerging Microbes & Infections

Visual and Motor Deficits in Grown-up Mice with Congenital Zika Virus Infection

(2017) Liyuan Cui et al.   EBioMedicine

Exosomes and other extracellular vesicles in neural cells and neurodegenerative diseases

(2016) Anna M. Janas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Exosomes as new diagnostic tools in CNS diseases

(2016) Katja M. Kanninen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Structural Basis of Zika Virus-Specific Antibody Protection

(2016) Haiyan Zhao et al.   CELL

Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation

(2016) Hongda Li et al.   Cell Stem Cell

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

(2016) Hengli Tang et al.   Cell Stem Cell

Mechanisms of Zika Virus Infection and Neuropathogenesis

(2016) David Olagnier et al.   DNA AND CELL BIOLOGY

Zika Virus-Induced Microcephaly and Its Possible Molecular Mechanism

(2016) Md Imam Faizan et al.   INTERVIROLOGY

Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse

(2016) Michael B. Dinkins et al.   JOURNAL OF NEUROSCIENCE

Extracellular vesicles round off communication in the nervous system

(2016) Vivian Budnik et al.   NATURE REVIEWS NEUROSCIENCE

Exosomes in Alzheimer's disease

(2016) Tarja Malm et al.   NEUROCHEMISTRY INTERNATIONAL

Exosomes in Viral Disease

(2016) Monique R. Anderson et al.   Neurotherapeutics

Neutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition

(2016) Wilhelm Stoffel et al.   Cell Death & Disease

Comparative Analysis Between Flaviviruses Reveals Specific Neural Stem Cell Tropism for Zika Virus in the Mouse Developing Neocortex

(2016) Jean-Baptiste Brault et al.   EBioMedicine

Inhibiting Extracellular Vesicle Release from Human Cardiosphere Derived Cells with Lentiviral Knockdown of nSMase2 Differentially Effects Proliferation and Apoptosis in Cardiomyocytes, Fibroblasts and Endothelial Cells In Vitro

(2016) Jennifer K. Lang et al.   PLoS One

Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction

(2015) Kobina Essandoh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Proteomics characterization of exosome cargo

(2015) Kevin L. Schey et al.   METHODS

Exosomes: Implications in HIV-1 Pathogenesis

(2015) Marisa Madison et al.   Viruses-Basel

The Dual Role of Exosomes in Hepatitis A and C Virus Transmission and Viral Immune Activation

(2015) Andrea Longatti   Viruses-Basel

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

(2015) Jian Zhang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Exosome-associated hepatitis C virus in cell cultures and patient plasma

(2014) Ziqing Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification

(2014) C.-R. Xu et al.   EMBO JOURNAL

Exosomes from Hepatitis C Infected Patients Transmit HCV Infection and Contain Replication Competent Viral RNA in Complex with Ago2-miR122-HSP90

(2014) Terence N. Bukong et al.   PLoS Pathogens

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

HCV transmission by hepatic exosomes establishes a productive infection

(2013) François-Loïc Cosset et al.   JOURNAL OF HEPATOLOGY

Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity

(2013) Jianhua Li et al.   NATURE IMMUNOLOGY

Exosomes: New players in cell–cell communication

(2012) Claudia Bang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Semaphorin 7A Contributes to West Nile Virus Pathogenesis through TGF- 1/Smad6 Signaling

(2012) H. Sultana et al.   JOURNAL OF IMMUNOLOGY

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Emerging Role of Neuronal Exosomes in the Central Nervous System

(2012) Mathilde Chivet et al.   Frontiers in Physiology

Exosomes: Small vesicles participating in intercellular communication

(2011) Anna-Kristin Ludwig et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization

(2011) Zohreh Khavandgar et al.   JOURNAL OF CELL BIOLOGY

Fusion Loop Peptide of the West Nile Virus Envelope Protein Is Essential for Pathogenesis and Is Recognized by a Therapeutic Cross-Reactive Human Monoclonal Antibody

(2009) H. Sultana et al.   JOURNAL OF IMMUNOLOGY

HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells

(2009) Metka Lenassi et al.   TRAFFIC

Single-particle cryo-electron microscopy of Rift Valley fever virus

(2009) Michael B. Sherman et al.   VIROLOGY

Regulation of information passing by synaptic transmission: A short review

(2008) Vito Di Maio   BRAIN RESEARCH