Chlorotoxin targets ERα/VASP signaling pathway to combat breast cancer

ER-α36 mediates cisplatin resistance in breast cancer cells through EGFR/HER-2/ERK signaling pathway

(2018) Linlin Zhu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial

(2018) Debu Tripathy et al.   LANCET ONCOLOGY

Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors

(2018) Theodoros T. Karalis et al.   MATRIX BIOLOGY

MTSS1 and SCAMP1 cooperate to prevent invasion in breast cancer

(2018) Jayakumar Vadakekolathu et al.   Cell Death & Disease

Discovery of Selective Estrogen Receptor Covalent Antagonists (SERCAs) for the treatment of ERa(WT) and ERa(MUT) breast cancer.

(2018) Xiaoling Puyang et al.   Cancer Discovery

Vectorized Delivery of Alpha-GalactosylCeramide and Tumor Antigen on Filamentous Bacteriophage fd Induces Protective Immunity by Enhancing Tumor-Specific T Cell Response

(2018) Rossella Sartorius et al.   Frontiers in Immunology

Molecular mechanisms mediating the neuroprotective role of the selective estrogen receptor modulator, bazedoxifene, in acute ischemic stroke: A comparative study with 17β-estradiol

(2017) Teresa Jover-Mengual et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Interleukin-17 augments tumor necrosis factor α-mediated increase of hypoxia-inducible factor-1α and inhibits vasodilator-stimulated phosphoprotein expression to reduce the adhesion of breast cancer cells

(2017) Kuang Changchun et al.   Oncology Letters

Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging

(2016) Liang Han et al.   ACS Nano

Cooperative Dynamics of AR and ER Activity in Breast Cancer

(2016) N. C. D'Amato et al.   MOLECULAR CANCER RESEARCH

Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE

(2016) G Carmona et al.   ONCOGENE

Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers

(2015) Sheng-Bin Peng et al.   CANCER CELL

Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion

(2015) Lucie Dardevet et al.   Toxins

The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3

(2014) Chao Qin et al.   BIOMATERIALS

Estrogen Receptor (ER)α-regulated Lipocalin 2 Expression in Adipose Tissue Links Obesity with Breast Cancer Progression

(2014) Brian G. Drew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Metastatic Tumor Growth and Metastasis via Targeting Metastatic Breast Cancer by Chlorotoxin-Modified Liposomes

(2014) Chao Qin et al.   MOLECULAR PHARMACEUTICS

A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1

(2014) T. Justin Rettenmaier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chlorotoxin-Fc Fusion Inhibits Release of MMP-2 from Pancreatic Cancer Cells

(2014) Samah El-Ghlban et al.   Biomed Research International

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer

(2013) Weiyi Toy et al.   NATURE GENETICS

Targeting BIG3–PHB2 interaction to overcome tamoxifen resistance in breast cancer cells

(2013) Tetsuro Yoshimaru et al.   Nature Communications

HIF-1α Acts Downstream of TNF-α to Inhibit Vasodilator-Stimulated Phosphoprotein Expression and Modulates the Adhesion and Proliferation of Breast Cancer Cells

(2012) Ke Su et al.   DNA AND CELL BIOLOGY

Platinum(IV)-chlorotoxin (CTX) conjugates for targeting cancer cells

(2012) Nora Graf et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Icariin exterts negative effects on human gastric cancer cell invasion and migration by vasodilator-stimulated phosphoprotein via Rac1 pathway

(2010) Yongping Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Green tea (−)-epigallocatechin-3-gallate down-regulates VASP expression and inhibits breast cancer cell migration and invasion by attenuating Rac1 activity

(2009) Yimin Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Annexin A2 Is a Molecular Target for TM601, a Peptide with Tumor-targeting and Anti-angiogenic Effects

(2009) Kamala Kesavan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological functions and clinical implications of oestrogen receptors alfa and beta in epithelial tissues

(2008) A. Morani et al.   JOURNAL OF INTERNAL MEDICINE

In Vivo MRI Detection of Gliomas by Chlorotoxin-Conjugated Superparamagnetic Nanoprobes

(2008) Conroy Sun et al.   Small

Inhibition of Tumor-Cell Invasion with Chlorotoxin-Bound Superparamagnetic Nanoparticles

(2008) Omid Veiseh et al.   Small