Article
Agriculture, Dairy & Animal Science
Xin Zhu, Lijuan Tao, Haiying Liu, Guiqin Yang
Summary: The aim of this study was to investigate the effects of dietary fermented feed addition on growth performance, immune organ indices, serum biochemical parameters, cecal odorous compound production, and bacterial community in broilers. The results showed that fermentation increased the abundance of Lactobacillus, Yeast, and Bacillus, as well as improved growth performance and immune organ development. Dietary fermented feed supplementation also reduced cecal odorous compound production and regulated the composition of the cecal microbiota.
Article
Veterinary Sciences
Yi Wan, Ruiyu Ma, Hongyi Zhang, Ling Li, Lilong Chai, Renrong Qi, Wei Liu, Junying Li, Yan Li, Kai Zhan
Summary: The study compared the effects of plastic net housing system (NRS) and floor litter housing system (LRS) on the duodenal and cecal microbiota of Shendan chicken, finding that NRS was superior in improving laying performance and intestinal morphology and microecological environment compared to LRS.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Microbiology
Zhengxiao He, Ranran Liu, Mengjie Wang, Qiao Wang, Jumei Zheng, Jiqiang Ding, Jie Wen, Alan G. Fahey, Guiping Zhao
Summary: Improving feed efficiency is crucial in animal production, and SCFAs play an important role in regulating feed efficiency. Genome-wide association studies revealed significant associations between SCFAs and genetic variations, and the taxa Christensenellaceae and Christensenellaceae_R-7_group were identified as representative microbiota contributing to feed efficiency.
Article
Immunology
Arno R. Bourgonje, Geesje Roo-Brand, Paola Lisotto, Mehdi Sadaghian Sadabad, Rosanne D. Reitsema, Marcus C. de Goffau, Klaas Nico Faber, Gerard Dijkstra, Hermie J. M. Harmsen
Summary: The IgG immune response in patients with IBD is mainly directed at intestinal bacterial genera associated with the small intestine microbiota, with lower responses against colonic-type commensal bacteria. These findings suggest a strong immunological exposure to potentially pathogenic intestinal bacteria in patients with IBD.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Ayman H. Abd El-Aziz, Mahmoud M. Abo Ghanima, Walaa F. Alsanie, Ahmed Gaber, Abd El-Wahab Alsenosy, Ahmed A. Easa, Sherif A. Moawed, Sayed Haidar Abbas Raza, Ahmed Elfadadny, Hany Abo Yossef, Wafaa M. Ghoneem, Mustafa Shukry, Amin Omar Hendawy, Khalid Mahrose
Summary: The present study found that supplementation with fructooligosaccharide (FOS) has positive effects on the growth performance, carcass characteristics, hematological and biochemical parameters, antioxidant status, and cecal microbiota of New Zealand White (NZW) and APRI rabbits. FOS supplementation improved the rabbits' body weight, daily weight gain, carcass traits, hematobiochemical parameters, and antioxidant status, while reducing the population of cecal pathogenic bacteria.
Article
Agriculture, Dairy & Animal Science
Melanie Martignon, Christine Burel, Laurent Cauquil, Sylvie Combes, Thierry Gidenne
Summary: The study shows that feed restriction can improve rabbit growth performance and nutrient digestibility, while fragmented feed distribution does not have a significant impact on rabbit digestive health.
Article
Microbiology
Xiao Xing Ye, Ke Yao Li, Ya Fei Li, Jia Ning Lu, Ping Ting Guo, Hao Yu Liu, Li Wen Zhou, Shuai Shuai Xue, Cai Yun Huang, Shao Ming Fang, Qian Fu Gan
Summary: This study found that supplementation of Clostridium butyricum improved the growth performance and digestibility of Ira rabbits. It also had an impact on the cecal microbiota structure and plasma metabolome.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Yinglu Liu, Jia Feng, Yamin Wang, Jing Lv, Jinghe Li, Lijuan Guo, Yuna Min
Summary: This study evaluated the effects of fermented corn-soybean meal mixed feed on intestinal barrier function and cecal microbiota in laying hens, finding that fermented feed can improve the intestinal morphology and functions of laying hens.
Article
Veterinary Sciences
Laura Montoro-Dasi, Laura Lorenzo-Rebenaque, Adrian Ramon-Moragues, Maria Teresa Perez-Gracia, Maria de Toro, Clara Marin, Arantxa Villagra
Summary: The study aimed to evaluate the effect of antibiotic feed supplementation on microbiota and productive performance in rabbits during the growing period. Results showed that antibiotic supplementation had no effect on microbiota composition and productive performance in the robust genetic line.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Yun Huang, Huijiao Lv, Yingchao Song, Congjiao Sun, Zifu Zhang, Sirui Chen
Summary: The study revealed subtle differences in cecal microbiota composition between high and low feed conversion rate groups, with Bacteroides potentially serving as biomarkers for feed efficiency. Metabolic pathways were found to be significantly enriched in the high efficiency group.
Article
Microbiology
Liqi Wang, Fuping Zhang, Hui Li, Shenglin Yang, Xiang Chen, Shuihua Long, Shenghong Yang, Yongxian Yang, Zhong Wang
Summary: In this study, it was found that the cecal microbiota can explain 10.1% of the individual differences in chicken weights. Specific bacterial genera were identified that can promote growth, while others can inhibit growth.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
El-Sayed M. Abdel-Kafy, Kamel I. Kamel, Marco Severgnini, Shama H. A. Morsy, Paola Cremonesi, Shereen S. Ghoneim, Gabriele Brecchia, Neama I. Ali, Yasmein Z. Abdel-Ghafar, Wael A. H. Ali, Hoda M. A. Shabaan
Summary: The microbiota, a large population of bacteria, protozoa, fungi, and algae that colonizes an animal's body surface, plays an important physiological role in digestion, immune system development, and the overall health of the animal. This study evaluated the microbiota composition in the jejunum and cecum of two rabbit breeds with different growth rates and found significant differences in microbiota between the two regions. Additionally, the study identified specific correlations between certain bacterial genera and body weight and weight gain, highlighting the potential impact of microbiota on rabbit productivity.
Article
Microbiology
Yongsheng Hao, Zhanqing Ji, Zhongjian Shen, Youjia Xue, Bo Zhang, Daxin Yu, Tong Liu, Dawei Luo, Guangnan Xing, Jing Tang, Shuisheng Hou, Ming Xie
Summary: The study investigated the effects of total dietary fiber (TDF) levels on cecal morphology and microbiota in ducks. The results showed that increasing TDF levels improved duck growth and cecal morphology. It also influenced the concentrations of short-chain fatty acids (SCFAs) and enriched specific bacteria in the cecum.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Rossy Guillen-Watson, Maria Arias-Andres, Keilor Rojas-Jimenez, Ingo S. Wehrtmann
Summary: Microplastics are a hazardous pollutant that can cause dysbiosis of the intestinal microbiome and impair the immune system of crayfish, as observed in this study using Procambarus clarkii as a model.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Sasa Miao, Zuopeng Hong, Huafeng Jian, Qianqian Xu, Yating Liu, Xiaoming Wang, Yan Li, Xinyang Dong, Xiaoting Zou
Summary: Coated sodium butyrate can improve the intestinal health of laying hens by regulating immune factors, enhancing antioxidant activity, increasing production of short-chain fatty acids, and modulating cecal microbiota.
Article
Nutrition & Dietetics
Etienne Labussiere, Caroline Achard, Serge Dubois, Sylvie Combes, Mathieu Castex, David Renaudeau
Summary: Supplementing live yeast can improve feed intake, energy retention, and attenuate the effects of HS on fecal microbiota composition in finishing boars.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Environmental Sciences
Alix Pierron, Manon Neves, Sylvie Puel, Yannick Lippi, Laura Soler, J. David Miller, Isabelle P. Oswald
Summary: The study revealed that NX, DON, and 3ANX have similar impacts on the intestine, mainly involving cell proliferation, differentiation, apoptosis, growth, immune and pro-inflammatory responses, with NX showing greater transcriptional impacts compared to DON.
Article
Nutrition & Dietetics
Martin Beaumont, Eloise Mussard, Celine Barilly, Corinne Lencina, Laure Gress, Louise Painteaux, Beatrice Gabinaud, Laurent Cauquil, Patrick Aymard, Cecile Canlet, Charlotte Paes, Christelle Knudsen, Sylvie Combes
Summary: This study found that in rabbits, the maturation of the gut microbiota at the suckling-to-weaning transition is primarily driven by the introduction of solid food, while the maturation of the intestinal epithelium is influenced by the developmental stage, solid food introduction, and suckling cessation.
JOURNAL OF NUTRITION
(2022)
Article
Food Science & Technology
Leonie Dopavogui, Arnaud Polizzi, Anne Fougerat, Pascal Gourbeyre, Chloe Terciolo, Wendy Klement, Philippe Pinton, Joelle Laffite, Anne-Marie Cossalter, Jean-Denis Bailly, Olivier Puel, Yannick Lippi, Claire Naylies, Herve Guillou, Isabelle P. Oswald, Nicolas Loiseau
Summary: Fumonisin B1 (FB1) is a widespread mycotoxin produced mainly in maize, and pigs and horses are most susceptible to it. FB1 exposure can cause diverse clinical symptoms. By analyzing the transcriptomes of four organs, common biological processes and tissue-specific processes related to lipid outcomes were identified in response to FB1 exposure.
Article
Biotechnology & Applied Microbiology
Marion Allaoua, Elsa Bonnafe, Pierre Etienne, Virginie Noirot, Jean-Francois Gabarrou, Adrien Castinel, Geraldine Pascal, Vincent Darbot, Michel Treilhou, Sylvie Combes
Summary: This study aimed to test the effectiveness of a carvacrol-based formulation in reducing C. jejuni load in broiler chickens and to study the impact of C. jejuni inoculation alone or combined with the product on the caecal microbiota. The results showed that the carvacrol-based product significantly decreased the C. jejuni load and that the combination of C. jejuni inoculation and the product increased the diversity and altered the structure of the microbial community.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Environmental Sciences
Marion Garofalo, Delphine Payros, Eric Oswald, Jean-Philippe Nougayrede, Isabelle P. Oswald
Summary: This study found that the dose of DON found in food can exacerbate DNA damage caused by etoposide, cisplatin, and phleomycin, but not the DNA damage caused by de-epoxy-deoxynivalenol (DOM-1). Ribotoxicity plays a key role in exacerbating DNA damage.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Toxicology
Laura Soler, Ingrid Miller, Chloe Terciolo, Karin Hummel, Katharina Noebauer, Manon Neves, Isabelle P. Oswald
Summary: We compared the protein composition of pig intestinal explants exposed to DON or NX and found that the changes in the extracellular proteome were different between the two toxins. DON decreased cell viability and caused cell destruction, while NX led to an enrichment of mitochondrial proteins in the secretome, which may be related to its ability to induce intestinal inflammation.
ARCHIVES OF TOXICOLOGY
(2022)
Editorial Material
Mycology
Olivier Puel, Benedikt Cramer, Isabelle P. Oswald, Hans-Ulrich Humpf
MYCOTOXIN RESEARCH
(2022)
Article
Microbiology
Charlotte Paes, Thierry Gidenne, Karine Bebin, Joel Duperray, Charly Gohier, Emeline Guene-Grand, Gwenael Rebours, Celine Barilly, Beatrice Gabinaud, Laurent Cauquil, Adrien Castinel, Geraldine Pascal, Vincent Darbot, Patrick Aymard, Anne-Marie Debrusse, Martin Beaumont, Sylvie Combes
Summary: This study in a rabbit model showed that early introduction of solid food can accelerate gut microbiota maturation, and plant polysaccharides ingestion has a significant impact on the cecal microbiota.
Article
Food Science & Technology
Carine Al-Ayoubi, Justin Oules, Elodie Person, Sandrine Bruel, Alyssa Bouville, Philippe Pinton, Isabelle P. Oswald, Emilien L. Jamin, Olivier Puel, Laura Soler
Summary: This study generated a panel of metabolites derived from in-house purified VerA, suggesting the bioactivation of VerA into an epoxide form. These qualitative analytic data provide valuable information for further precise metabolism study of VerA.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Cell Biology
Eloise Mussard, Corinne Lencina, Lise Gallo, Celine Barilly, Maryse Poli, Katia Feve, Mikael Albin, Laurent Cauquil, Christelle Knudsen, Caroline Achard, Guillaume Devailly, Laura Soler, Sylvie Combes, Martin Beaumont
Summary: Intestinal organoids generated from piglets retained a location-specific phenotype but not a developmental stage-specific phenotype. The luminal environment of the organoids was not representative of the in vivo environment, suggesting that reproducing the luminal environment might improve the physiological relevance of intestinal organoids.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Guillermo Martinez Boggio, Christel Marie-Etancelin, Jean-Marie Menras, Regis Tomas, Marie-Luce Chemit, Beatrice Gabinaud, Geraldine Pascal, Annabelle Meynadier
Summary: Ruminants can convert plants into human food thanks to rumen bacteria, which can transform feed into microbial proteins and directly contribute to the composition of high-quality milk. In this study, daily records of milk yield, somatic cell score, and 17 milk components were obtained from 795 Lacaune dairy ewes, and ruminal samples were sequenced to determine the bacterial composition. The analysis revealed 2,059 OTUs attributed to 11 phyla, with Bacteroidota (50.6%) and Firmicutes (43.6%) being the most representative phyla. The shared datasets provided in this study will be valuable for investigating the relationship between rumen bacteria and milk traits, as well as proposing solutions to improve animal production and health.
Article
Biochemistry & Molecular Biology
Martin Beaumont, Corinne Lencina, Katia Feve, Celine Barilly, Laurence Le-Normand, Sylvie Combes, Guillaume Devailly, Gaelle Boudry
Summary: The disruption of the primocolonizing gut microbiota alters epithelial innate immunity in the colon and imprints stem cells, which could have long-term consequences for gut health. Colistin, an antibiotic, was used in a newborn piglet model to deplete specific gram-negative bacteria in the neonatal gut microbiota. The depletion of these bacteria resulted in altered gene expression in the colon epithelium, decreased toll-like receptor 4 (TLR4) and lysozyme (LYZ) levels, and an increased concentration of succinate in the colon.
Article
Microbiology
Martin Beaumont, Corinne Lencina, Allan Bertide, Lise Gallo, Celine Barilly, Christelle Marrauld, Laurent Cauquil, Arnaud Samson, Sylvie Combes
Summary: This study suggests that the gut microbiota during the suckling period is not a major factor underlying the susceptibility of piglets to post-weaning diarrhea (PWD).
MICROBIOLOGY SPECTRUM
(2023)