Exosome-Like Vesicles as New Mediators and Therapeutic Targets for Treating Insulin Resistance and β-Cell Mass Failure in Type 2 Diabetes Mellitus

Exosomal cargo-loading and synthetic exosome-mimics as potential therapeutic tools

(2018) Song-pei Li et al.   ACTA PHARMACOLOGICA SINICA

Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds

(2018) Ammad Ahmad Farooqi et al.   BIOTECHNOLOGY ADVANCES

Altered Extracellular Vesicle Concentration, Cargo and Function in Diabetes Mellitus

(2018) David W. Freeman et al.   DIABETES

Regulation and mechanisms of extracellular vesicle biogenesis and secretion

(2018) Crislyn D’Souza-Schorey et al.   Essays in Biochemistry

Extracellular Vesicles from Hypoxic Adipocytes and Obese Subjects Reduce Insulin-Stimulated Glucose Uptake

(2018) Justyna Mleczko et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPARγ

(2018) Yang Yu et al.   Theranostics

Human Mesenchymal Stem Cell Derived Exosomes Alleviate Type 2 Diabetes Mellitus by Reversing Peripheral Insulin Resistance and Relieving β-Cell Destruction

(2018) Yaoxiang Sun et al.   ACS Nano

Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways

(2018) Ming Song et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

MicroRNAs 106b and 222 Improve Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes via Pancreatic β-Cell Proliferation

(2017) Sohei Tsukita et al.   EBioMedicine

Recent advances of exosomes in immune modulation and autoimmune diseases

(2016) Lina Tan et al.   AUTOIMMUNITY

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity

(2016) Chiara Cianciaruso et al.   DIABETES

Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice

(2016) Audrey Jalabert et al.   DIABETOLOGIA

Neutral Ceramidase Secreted Via Exosome Protects Against Palmitate-Induced Apoptosis in INS-1 Cells

(2016) S. Tang et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass

(2016) Monica J. Hubal et al.   Obesity

Pathologic function and therapeutic potential of exosomes in cardiovascular disease

(2015) Shaina Ailawadi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells

(2015) Claudiane Guay et al.   Cell Communication and Signaling

Exosomes: Natural Carriers for siRNA Delivery

(2015) Lalit Kumar et al.   CURRENT PHARMACEUTICAL DESIGN

Exosome mediated communication within the tumor microenvironment

(2015) Lara Milane et al.   JOURNAL OF CONTROLLED RELEASE

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

(2015) Huilin Shao et al.   Nature Communications

Nanovesicles engineered from ES cells for enhanced cell proliferation

(2014) Dayeong Jeong et al.   BIOMATERIALS

Exosomes in Neurologic and Psychiatric Disorders

(2014) Irene Tsilioni et al.   CLINICAL THERAPEUTICS

Novel therapeutics for type 2 diabetes: insulin resistance

(2014) Q.-A. Altaf et al.   DIABETES OBESITY & METABOLISM

Myokines in insulin resistance and type 2 diabetes

(2014) Kristin Eckardt et al.   DIABETOLOGIA

Exosomes participate in the alteration of muscle homeostasis during lipid-induced insulin resistance in mice

(2014) Hala Aswad et al.   DIABETOLOGIA

Effect of extracellular vesicles of human adipose tissue on insulin signaling in liver and muscle cells

(2014) Mariëtte E.G. Kranendonk et al.   Obesity

Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors

(2013) Su Chul Jang et al.   ACS Nano

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

(2013) Marina Colombo et al.   JOURNAL OF CELL SCIENCE

Human adipocyte extracellular vesicles in reciprocal signaling between adipocytes and macrophages

(2013) Mariëtte E.G. Kranendonk et al.   Obesity

MicroRNAs Regulated by Adiponectin as Novel Targets for Controlling Adipose Tissue Inflammation

(2012) Qian Ge et al.   ENDOCRINOLOGY

Exosome mimetics: a novel class of drug delivery systems

(2012) Raymond Schiffelers et al.   International Journal of Nanomedicine

Adipokines identified as new downstream targets for adiponectin: lessons from adiponectin-overexpressing or -deficient mice

(2011) Qian Ge et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance

(2009) Z.-b. Deng et al.   DIABETES