Exogenous Addition of 25-Hydroxycholesterol Reduces Level of Very Long-Chain Fatty Acids in X-Linked Adrenoleukodystrophy

25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism

(2018) Ying Liu et al.   JOURNAL OF LIPID RESEARCH

25-Hydroxycholesterol protects against acute lung injury via targeting MD-2

(2018) Wei Ouyang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model

(2017) Chunfeng Li et al.   IMMUNITY

Cholesterol 25-hydroxylase acts as a host restriction factor on pseudorabies virus replication

(2017) Jiang Wang et al.   JOURNAL OF GENERAL VIROLOGY

Adrenoleukodystrophy – neuroendocrine pathogenesis and redefinition of natural history

(2016) Stephan Kemp et al.   Nature Reviews Endocrinology

Oxysterols in Metabolic Syndrome: From Bystander Molecules to Bioactive Lipids

(2016) Owein Guillemot-Legris et al.   TRENDS IN MOLECULAR MEDICINE

25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome

(2016) Jiho Jang et al.   Nature Communications

Enzymatic characterization of ELOVL1, a key enzyme in very long-chain fatty acid synthesis

(2015) Martin J.A. Schackmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

X-linked adrenoleukodystrophy: Clinical, metabolic, genetic and pathophysiological aspects

(2012) Stephan Kemp et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol

(2012) Su-Yang Liu et al.   IMMUNITY

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

(2012) Mathieu Blanc et al.   IMMUNITY

The role of ELOVL1 in very long-chain fatty acid homeostasis and X-linked adrenoleukodystrophy

(2010) Rob Ofman et al.   EMBO Molecular Medicine

Lovastatin in X-Linked Adrenoleukodystrophy

(2010) Marc Engelen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Liver X Receptors (LXR) as Therapeutic Targets in Dyslipidemia

(2008) Jerzy Bełtowski   Cardiovascular Therapeutics