Readily Accessible Bulky Iron Catalysts exhibiting Site Selectivity in the Oxidation of Steroidal Substrates

The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

(2016) Tim Cernak et al.   CHEMICAL SOCIETY REVIEWS

Site-Selective Aliphatic C–H Chlorination Using N-Chloroamides Enables a Synthesis of Chlorolissoclimide

(2016) Ryan K. Quinn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tuning Reactivity and Selectivity in Hydrogen Atom Transfer from Aliphatic C–H Bonds to Alkoxyl Radicals: Role of Structural and Medium Effects

(2015) Michela Salamone et al.   ACCOUNTS OF CHEMICAL RESEARCH

Molecular iron complexes as catalysts for selective C–H bond oxygenation reactions

(2015) A. C. Lindhorst et al.   CHEMICAL COMMUNICATIONS

Expanding the toolbox of organic chemists: directed evolution of P450 monooxygenases as catalysts in regio- and stereoselective oxidative hydroxylation

(2015) Gheorghe-Doru Roiban et al.   CHEMICAL COMMUNICATIONS

Enhanced Reactivity in Hydrogen Atom Transfer from Tertiary Sites of Cyclohexanes and Decalins via Strain Release: Equatorial C–H Activation vs Axial C–H Deactivation

(2015) Michela Salamone et al.   JOURNAL OF ORGANIC CHEMISTRY

Scalable C–H Oxidation with Copper: Synthesis of Polyoxypregnanes

(2015) Yi Yang See et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzymatic hydroxylation of an unactivated methylene C–H bond guided by molecular dynamics simulations

(2015) Alison R. H. Narayan et al.   Nature Chemistry

Comparative Study of the Limitations and Challenges in Atom-Transfer C–H Oxidations

(2015) Ashley M. Adams et al.   ORGANIC LETTERS

The Iron(II) Complex [Fe(CF3SO3)2(mcp)] as a Convenient, Readily Available Catalyst for the Selective Oxidation of Methylenic Sites in Alkanes

(2014) Mercè Canta et al.   ADVANCED SYNTHESIS & CATALYSIS

Directing Group-Controlled Regioselectivity in an Enzymatic C–H Bond Oxygenation

(2014) Solymar Negretti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-Selective Oxidation of Unactivated C sp 3H Bonds with Hypervalent Iodine(III) Reagents

(2013) Shin A. Moteki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New Site-Selective Organoradical Based on Hypervalent Iodine Reagent for Controlled Alkane sp3CH Oxidations

(2013) Toshifumi Dohi et al.   ChemCatChem

Regioselective Oxidation of Nonactivated Alkyl C–H Groups Using Highly Structured Non-Heme Iron Catalysts

(2013) Laura Gómez et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalyst-Controlled Aliphatic C–H Oxidations with a Predictive Model for Site-Selectivity

(2013) Paul E. Gormisky et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Iron Catalyst for Oxidation of Alkyl CH Bonds Showing Enhanced Selectivity for Methylenic Sites

(2012) Irene Prat et al.   CHEMISTRY-A EUROPEAN JOURNAL

Controlled Oxidation of Remote sp3 C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity

(2012) Kaidong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient, Regioselective, and Stereospecific Oxidation of Aliphatic C–H Groups with H2O2, Catalyzed by Aminopyridine Manganese Complexes

(2012) Roman V. Ottenbacher et al.   ORGANIC LETTERS

Adding Aliphatic C-H Bond Oxidations to Synthesis

(2012) M. C. White   SCIENCE

Tuning P450 Enzymes as Oxidation Catalysts

(2012) Rudi Fasan   ACS Catalysis

If CH Bonds Could Talk: Selective CH Bond Oxidation

(2011) Timothy Newhouse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Steric Modifications Tune the Regioselectivity of the Alkane Oxidation Catalyzed by Non-Heme Iron Complexes

(2011) Yu He et al.   INORGANIC CHEMISTRY

Predictable Stereoselective and Chemoselective Hydroxylations and Epoxidations with P450 3A4

(2011) Aaron T. Larsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution

(2011) Sabrina Kille et al.   Nature Chemistry

Efficient stereo- and regioselective hydroxylation of alkanes catalysed by a bulky polyoxometalate

(2010) Keigo Kamata et al.   Nature Chemistry

Selectivity enhancement in functionalization of C–H bonds: A review

(2010) Georgiy B. Shul'pin   ORGANIC & BIOMOLECULAR CHEMISTRY

Strain Release in CH Bond Activation?

(2009) Ke Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereospecific CH Oxidation with H2O2Catalyzed by a Chemically Robust Site-Isolated Iron Catalyst

(2009) Laura Gómez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Cyclopamine Using a Biomimetic and Diastereoselective Approach

(2009) Athanassios Giannis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of (+)-Cephalostatin 1

(2009) Kevin C. Fortner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Asymmetric Olefincis-Dihydroxylation with 97 % Enantiomeric Excess

(2008) Ken Suzuki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION