Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease

Krebs cycle rewired for macrophage and dendritic cell effector functions

(2017) Dylan Gerard Ryan et al.   FEBS LETTERS

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth

(2016) Jared Wallace et al.   PLoS One

miR-155 Deletion in Female Mice Prevents Diet-Induced Obesity

(2016) Andrew D. Gaudet et al.   Scientific Reports

miR-146a-mediated suppression of the inflammatory response in human adipocytes

(2016) Julian Roos et al.   Scientific Reports

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

The cell biology of fat expansion

(2015) Joseph M. Rutkowski et al.   JOURNAL OF CELL BIOLOGY

Anti-Inflammatory Role of MicroRNA-146a in the Pathogenesis of Diabetic Nephropathy

(2015) K. Bhatt et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Control of macrophage metabolism and activation by mTOR and Akt signaling

(2015) Anthony J. Covarrubias et al.   SEMINARS IN IMMUNOLOGY

MicroRNA-146a regulates ICOS–ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres

(2015) Alvin Pratama et al.   Nature Communications

MicroRNA-146a constrains multiple parameters of intestinal immunity and increases susceptibility to DSS colitis

(2015) Marah C. Runtsch et al.   Oncotarget

miR-155 Promotes T Follicular Helper Cell Accumulation during Chronic, Low-Grade Inflammation

(2014) Ruozhen Hu et al.   IMMUNITY

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

Decreased Serum Level of miR-146a as Sign of Chronic Inflammation in Type 2 Diabetic Patients

(2014) Lucy Baldeón R. et al.   PLoS One

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

(2014) A. Chatzigeorgiou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis C virus and human miR-122: insights from the bench to the clinic

(2014) Joyce A Wilson et al.   Current Opinion in Virology

Decreased miR-146 expression in peripheral blood mononuclear cells is correlated with ongoing islet autoimmunity in type 1 diabetes patients 1型糖尿病患者外周血单个核细胞miR-146表达下调与胰岛持续免疫失衡相关

(2014) Minglan Yang et al.   Journal of Diabetes

Association between Class III Obesity (BMI of 40–59 kg/m2) and Mortality: A Pooled Analysis of 20 Prospective Studies

(2014) Cari M. Kitahara et al.   PLOS MEDICINE

K63 Polyubiquitination and Activation of mTOR by the p62-TRAF6 Complex in Nutrient-Activated Cells

(2013) Juan F. Linares et al.   MOLECULAR CELL

miR-146acontrols the resolution of T cell responses in mice

(2012) Lili Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epistasis between MicroRNAs 155 and 146a during T Cell-Mediated Antitumor Immunity

(2012) Thomas B. Huffaker et al.   Cell Reports

miR-146a–Mediated Extracellular Matrix Protein Production in Chronic Diabetes Complications

(2011) Biao Feng et al.   DIABETES

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes

(2011) M. Balasubramanyam et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

Annual Medical Spending Attributable To Obesity: Payer-And Service-Specific Estimates

(2009) Eric A. Finkelstein et al.   HEALTH AFFAIRS

The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

(2009) W.-L. Yang et al.   SCIENCE

Insulin Resistance and Hyperinsulinemia: Is hyperinsulinemia the cart or the horse?

(2008) M. H. Shanik et al.   DIABETES CARE