Generation and Reaction of Carbamoyl Anions in Flow: Applications in the Three-Component Synthesis of Functionalized α-Ketoamides
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Title
Generation and Reaction of Carbamoyl Anions in Flow: Applications in the Three-Component Synthesis of Functionalized α-Ketoamides
Authors
Keywords
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Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 55, Issue 17, Pages 5327-5331
Publisher
Wiley
Online
2016-03-19
DOI
10.1002/anie.201601386
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Note: Only part of the references are listed.- Formamidine hydrochloride as an amino surrogate: I2-catalyzed oxidative amidation of aryl methyl ketones leading to free (N–H) α-ketoamides
- (2015) Shan Liu et al. ORGANIC & BIOMOLECULAR CHEMISTRY
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- (2013) Julio C. Pastre et al. CHEMICAL SOCIETY REVIEWS
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- (2013) D. Tyler McQuade et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2012) Aiichiro Nagaki et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- Copper-catalyzed direct oxidative synthesis of α-ketoamides from aryl methyl ketones, amines, and molecular oxygen
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- (2011) Heejin Kim et al. Nature Communications
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- (2010) Jonathan P. McMullen et al. Annual Review of Analytical Chemistry
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- (2010) Zhiguo Zhang et al. CHEMICAL COMMUNICATIONS
- Photochemical type II reaction of atropchiral benzoylformamides to point chiral oxazolidin-4-ones. Axial chiral memory leading to enantiomeric resolution of photoproducts
- (2010) Josepha L. Jesuraj et al. CHEMICAL COMMUNICATIONS
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- Microchemical systems for continuous-flow synthesis
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- Protecting-group-free synthesis as an opportunity for invention
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