A cancer-associated point mutation disables the steric gate of human PrimPol
Published 2019 View Full Article
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Title
A cancer-associated point mutation disables the steric gate of human PrimPol
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-02-04
DOI
10.1038/s41598-018-37439-0
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- (2018) María I Martínez-Jiménez et al. NUCLEIC ACIDS RESEARCH
- Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model
- (2017) Chloe F. Moss et al. NUCLEIC ACIDS RESEARCH
- Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired
- (2017) Paulina H. Wanrooij et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2017) Rubén Torregrosa-Muñumer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides
- (2016) Kaori Kobayashi et al. CELL CYCLE
- PrimPol Is Required for Replicative Tolerance of G Quadruplexes in Vertebrate Cells
- (2016) Davide Schiavone et al. MOLECULAR CELL
- TruePrime is a novel method for whole-genome amplification from single cells based on TthPrimPol
- (2016) Ángel J. Picher et al. Nature Communications
- Structure and mechanism of human PrimPol, a DNA polymerase with primase activity
- (2016) O. Rechkoblit et al. Science Advances
- Alternative solutions and new scenarios for translesion DNA synthesis by human PrimPol
- (2015) María I. Martínez-Jiménez et al. DNA REPAIR
- Kinetic Analysis of Human PrimPol DNA Polymerase Activity Reveals a Generally Error-Prone Enzyme Capable of Accurately Bypassing 7,8-Dihydro-8-oxo-2′-deoxyguanosine
- (2014) Maroof K. Zafar et al. BIOCHEMISTRY
- Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2·DNA and Top2·RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)
- (2014) Rui Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular dissection of the domain architecture and catalytic activities of human PrimPol
- (2014) Benjamin A. Keen et al. NUCLEIC ACIDS RESEARCH
- ATP insertion opposite 8-oxo-deoxyguanosine by Pol4 mediates error-free tolerance in Schizosaccharomyces pombe
- (2014) Guillermo Sastre-Moreno et al. NUCLEIC ACIDS RESEARCH
- hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity
- (2013) Li Wan et al. EMBO REPORTS
- PrimPol, an Archaic Primase/Polymerase Operating in Human Cells
- (2013) Sara García-Gómez et al. MOLECULAR CELL
- Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair
- (2013) Medini Manohar Ghodgaonkar et al. MOLECULAR CELL
- Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors
- (2013) Scott A. Lujan et al. MOLECULAR CELL
- Aprataxin resolves adenylated RNA–DNA junctions to maintain genome integrity
- (2013) Percy Tumbale et al. NATURE
- Repriming of DNA synthesis at stalled replication forks by human PrimPol
- (2013) Silvana Mourón et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure-function analysis of ribonucleotide bypass by B family DNA replicases
- (2013) A. R. Clausen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase
- (2013) Nigel C. Brissett et al. Cell Reports
- Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
- (2012) Martin A.M. Reijns et al. CELL
- Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛ
- (2012) Jessica S. Williams et al. DNA REPAIR
- Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ
- (2012) Anders R. Clausen et al. DNA REPAIR
- Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events
- (2012) J. Liu et al. GENOME RESEARCH
- Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity
- (2012) Bjoern Hiller et al. JOURNAL OF EXPERIMENTAL MEDICINE
- RNase H2-Initiated Ribonucleotide Excision Repair
- (2012) Justin L. Sparks et al. MOLECULAR CELL
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Ribonucleotides and manganese ions improve non-homologous end joining by human Polµ
- (2012) Maria Jose Martin et al. NUCLEIC ACIDS RESEARCH
- Unlocking the Sugar “Steric Gate” of DNA Polymerases
- (2011) Jessica A. Brown et al. BIOCHEMISTRY
- Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
- (2011) Assaf C. Bester et al. CELL
- Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases
- (2011) Danielle L. Watt et al. DNA REPAIR
- Structure of a Preternary Complex Involving a Prokaryotic NHEJ DNA Polymerase
- (2011) Nigel C. Brissett et al. MOLECULAR CELL
- Molecular architecture of a multifunctional MCM complex
- (2011) June Sanchez-Berrondo et al. NUCLEIC ACIDS RESEARCH
- Identification of a Novel Type of Spacer Element Required for Imprinting in Fission Yeast
- (2011) Suha Sayrac et al. PLoS Genetics
- Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases
- (2010) S. A. Nick McElhinny et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cohesin acetylation speeds the replication fork
- (2009) Marie-Emilie Terret et al. NATURE
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