An In-tether Chiral Center Modulates the Helicity, Cell Permeability, and Target Binding Affinity of a Peptide

Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction

(2016) Thomas E. Speltz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Peptide stapling techniques based on different macrocyclisation chemistries

(2015) Yu Heng Lau et al.   CHEMICAL SOCIETY REVIEWS

Towards understanding cell penetration by stapled peptides

(2015) Qian Chu et al.   MedChemComm

Constraining Cyclic Peptides To Mimic Protein Structure Motifs

(2014) Timothy A. Hill et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modulators of Protein–Protein Interactions

(2014) Lech-Gustav Milroy et al.   CHEMICAL REVIEWS

Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

(2014) Loren D. Walensky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dynamic covalent side-chain cross-links via intermolecular oxime or hydrazone formation from bifunctional peptides and simple organic linkers

(2014) Conor M. Haney et al.   JOURNAL OF PEPTIDE SCIENCE

Stitched α-Helical Peptides via Bis Ring-Closing Metathesis

(2014) Gerard J. Hilinski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functionalised staple linkages for modulating the cellular activity of stapled peptides

(2014) Yu Heng Lau et al.   Chemical Science

Enhancement of the helical content and stability induced in a linear oligopeptide by ani, i+4 intramolecularly double stapled, overlapping, bicyclic [31, 22, 5]-(E)ene motif

(2013) Daniela Mazzier et al.   BIOPOLYMERS

Inhibition of α-helix-mediated protein–protein interactions using designed molecules

(2013) Valeria Azzarito et al.   Nature Chemistry

Convergent diversity-oriented side-chain macrocyclization scan for unprotected polypeptides

(2013) Yekui Zou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy

(2013) Yong S. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational Design of Proteolytically Stable, Cell-Permeable Peptide-Based Selective Mcl-1 Inhibitors

(2012) Avinash Muppidi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the Stapled p53 Peptide Bound to Mdm2

(2011) Sohee Baek et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design and Structure of Stapled Peptides Binding to Estrogen Receptors

(2011) Chris Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural and biological mimicry of protein surface recognition by  / -peptide foldamers

(2009) W. S. Horne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Peptidic Peptidomimetics

(2008) Dieter Seebach et al.   ACCOUNTS OF CHEMICAL RESEARCH

Contemporary strategies for the stabilization of peptides in the α-helical conformation

(2008) Laura K Henchey et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Synthesis and Conformational Analysis of a Cyclic Peptide Obtained viaitoi+4 Intramolecular Side-Chain to Side-Chain Azide−Alkyne 1,3-Dipolar Cycloaddition

(2008) Sonia Cantel et al.   JOURNAL OF ORGANIC CHEMISTRY