A critical evaluation of TRPA1-mediated locomotor behavior in zebrafish as a screening tool for novel anti-nociceptive drug discovery

A zebrafish and mouse model for selective pruritus via direct activation of TRPA1

(2018) Kali Esancy et al.   eLife

Utilizing Zebrafish Visual Behaviors in Drug Screening for Retinal Degeneration

(2017) Logan Ganzen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for animal nociception

(2017) Oscar M. Arenas et al.   NATURE NEUROSCIENCE

A novel zebrafish-based model of nociception

(2017) J. Christopher Taylor et al.   PHYSIOLOGY & BEHAVIOR

Zebrafish Locomotor Responses Reveal Irritant Effects of Fine Particulate Matter Extracts and a Role for TRPA1

(2017) Joey S Stevens et al.   TOXICOLOGICAL SCIENCES

Sensitivities of Two Zebrafish TRPA1 Paralogs to Chemical and Thermal Stimuli Analyzed in Heterologous Expression Systems

(2016) Mai Oda et al.   CHEMICAL SENSES

Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia

(2016) Elisangela Bressan et al.   PAIN

Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain

(2016) Katrin Kistner et al.   Scientific Reports

Definition of two agonist types at the mammalian cold-activated channel TRPM8

(2016) Annelies Janssens et al.   eLife

TRP channel mediated neuronal activation and ablation in freely behaving zebrafish

(2015) Shijia Chen et al.   NATURE METHODS

TRPA1 as a drug target—promise and challenges

(2015) Jun Chen et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Modeling Nociception in Zebrafish: A Way Forward for Unbiased Analgesic Discovery

(2015) Andrew Curtright et al.   PLoS One

Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain

(2013) Ryosuke Kojima et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the rat

(2013) Michael R. Due et al.   JOURNAL OF NEUROCHEMISTRY

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(2013) Veronica Gonzalez-Nunez et al.   MOLECULAR MEDICINE

Towards a Comprehensive Catalog of Zebrafish Behavior 1.0 and Beyond

(2013) Allan V. Kalueff et al.   Zebrafish

Activation characteristics of transient receptor potential ankyrin 1 and its role in nociception

(2011) Manish Raisinghani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Differences of acute versus chronic ethanol exposure on anxiety-like behavioral responses in zebrafish

(2011) Priya Mathur et al.   BEHAVIOURAL BRAIN RESEARCH

Emergence of Functional Spinal Delta Opioid Receptors After Chronic Ethanol Exposure

(2011) Richard M. van Rijn et al.   BIOLOGICAL PSYCHIATRY

Transient receptor potential channels as therapeutic targets

(2011) Magdalene M. Moran et al.   NATURE REVIEWS DRUG DISCOVERY

Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

(2011) Jun Chen et al.   PAIN

Pungent General Anesthetics Activate Transient Receptor Potential-A1 to Produce Hyperalgesia and Neurogenic Bronchoconstriction

(2010) Helge Eilers et al.   ANESTHESIOLOGY

High-Throughput Behavioral Screens: the First Step towards Finding Genes Involved in Vertebrate Brain Function Using Zebrafish

(2010) Robert Gerlai   MOLECULES

Mu Opioid Receptor from the Zebrafish Exhibits Functional Characteristics as Those of Mammalian Mu Opioid Receptor

(2009) Ezequiel Marron Fdez. de Velasco et al.   Zebrafish

Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function

(2008) D. A. Prober et al.   JOURNAL OF NEUROSCIENCE

HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- and Neuropathy-Induced Mechanical Hypersensitivity

(2008) Samer R Eid et al.   Molecular Pain