Ergosterol Ameliorates Diabetic Nephropathy by Attenuating Mesangial Cell Proliferation and Extracellular Matrix Deposition via the TGF-β1/Smad2 Signaling Pathway

Tangeretin inhibits high glucose-induced extracellular matrix accumulation in human glomerular mesangial cells

(2018) Fang Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Repression of microRNA-382 inhibits glomerular mesangial cell proliferation and extracellular matrix accumulation via FoxO1 in mice with diabetic nephropathy

(2018) Shan Wang et al.   CELL PROLIFERATION

SIRT3 Facilitates Amniotic Fluid Stem Cells to Repair Diabetic Nephropathy Through Protecting Mitochondrial Homeostasis by Modulation of Mitophagy

(2018) Jianxun Feng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Ergosterol Attenuates LPS-Induced Myocardial Injury by Modulating Oxidative Stress and Apoptosis in Rats

(2018) Jianjun Xu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Role of Matrix Metalloproteinases in Degenerative Kidney Disorders

(2018) Shifa Narula et al.   CURRENT MEDICINAL CHEMISTRY

Antidiabetic Activity of Ergosterol from Pleurotus Ostreatus in KK-Ay Mice with Spontaneous Type 2 Diabetes Mellitus

(2018) Mingrui Xiong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

In vitro and ex vivo anti-fibrotic effects of LY2109761, a small molecule inhibitor against TGF-β

(2018) Theerut Luangmonkong et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chrysin Inhibits Advanced Glycation End Products-Induced Kidney Fibrosis in Renal Mesangial Cells and Diabetic Kidneys

(2018) Eun-Jung Lee et al.   Nutrients

Plant sterols lower LDL-cholesterol and triglycerides in dyslipidemic individuals with or at risk of developing type 2 diabetes; a randomized, double-blind, placebo-controlled study

(2018) Elke A. Trautwein et al.   Nutrition & Diabetes

Transforming growth factor-β1 in children with diabetic nephropathy

(2018) Happy Sawires et al.   PEDIATRIC NEPHROLOGY

Scoparone attenuates high glucose-induced extracellular matrix accumulation in rat mesangial cells

(2017) Yunqian Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dencichine ameliorates kidney injury in induced type II diabetic nephropathy via the TGF-β/Smad signalling pathway

(2017) Li Jie et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Selective activation of epidermal growth factor receptor in renal proximal tubule induces tubulointerstitial fibrosis

(2017) Jessica M. Overstreet et al.   FASEB JOURNAL

Effects of Ergosterol on COPD in Mice via JAK3/STAT3/NF-κB Pathway

(2017) Wang Huan et al.   INFLAMMATION

Prevention of renal apoB retention is protective against diabetic nephropathy: role of TGF-β inhibition

(2017) Patricia G. Wilson et al.   JOURNAL OF LIPID RESEARCH

Modelling diabetic nephropathy in mice

(2017) Kengo Azushima et al.   Nature Reviews Nephrology

Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy

(2017) Magdalena Krochmal et al.   Scientific Reports

C66 ameliorates diabetic nephropathy in mice by both upregulating NRF2 function via increase in miR-200a and inhibiting miR-21

(2016) Hao Wu et al.   DIABETOLOGIA

Renoprotective effect of berberineviaregulating the PGE2-EP1-Gαq-Ca2+signalling pathway in glomerular mesangial cells of diabetic rats

(2016) Wei-Jian Ni et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Recovery of ergosterol from the medicinal mushroom, Ganoderma tsugae var. Janniae, with a molecularly imprinted polymer derived from a cleavable monomer-template composite

(2016) Shima N.N.S. Hashim et al.   JOURNAL OF CHROMATOGRAPHY A

Aptamers: novel diagnostic and therapeutic tools for diabetes mellitus and metabolic diseases

(2016) Jingping Hu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

MicroRNA-26a inhibits TGF-β-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy

(2015) Kenichi Koga et al.   DIABETOLOGIA

Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin-induced diabetic nephropathy in rats

(2015) Wei-Jian Ni et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ergosterol Alleviates Kidney Injury in Streptozotocin-Induced Diabetic Mice

(2015) Li Ang et al.   Evidence-based Complementary and Alternative Medicine

Advances in Microalgae-Derived Phytosterols for Functional Food and Pharmaceutical Applications

(2015) Xuan Luo et al.   Marine Drugs

Administration of Danhong Injection to diabetic db/db mice inhibits the development of diabetic retinopathy and nephropathy

(2015) Mengyang Liu et al.   Scientific Reports

A Glimpse of Matrix Metalloproteinases in Diabetic Nephropathy

(2014) X. Xu et al.   CURRENT MEDICINAL CHEMISTRY

Matrix metalloproteinase-9 deficiency attenuates diabetic nephropathy by modulation of podocyte functions and dedifferentiation

(2014) Szu-Yuan Li et al.   KIDNEY INTERNATIONAL

Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease

(2013) Helena Gylling et al.   ATHEROSCLEROSIS

Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus

(2013) Lishuai Ma et al.   FOOD CHEMISTRY

Inhibition of collagen I accumulation reduces glomerulosclerosis by a Hic-5-dependent mechanism in experimental diabetic nephropathy

(2013) Nick Hornigold et al.   LABORATORY INVESTIGATION

Mesangial cell biology

(2012) Hanna E. Abboud   EXPERIMENTAL CELL RESEARCH

Effects of Combined Endothelin A Receptor and Renin-Angiotensin System Blockade on the Course of End-Organ Damage in 5/6 Nephrectomized Ren-2 Hypertensive Rats

(2012) Ivana Vanecková et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide

(2011) P. Yuan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential

(2010) H. Y. Chen et al.   DIABETES

Transforming growth factor-β/connective tissue growth factor axis in the kidney

(2007) Weier Qi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Moderately elevated plant sterol levels are associated with reduced cardiovascular risk—The LASA study

(2006) Klaus Fassbender et al.   ATHEROSCLEROSIS