Breast Cancer Stem Cell Potent Copper(II)-Non-Steroidal Anti-Inflammatory Drug Complexes

The Biological Activity of Zeise’s Salt and its Derivatives

(2015) Sandra Meieranz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Necroptosis-Inducing Rhenium(V) Oxo Complexes

(2015) Kogularamanan Suntharalingam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The cancer stem cell gamble

(2015) J. Kaiser   SCIENCE

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition

(2015) Rebecca Lamb et al.   Oncotarget

The Prodrug Platin-A: Simultaneous Release of Cisplatin and Aspirin

(2014) Rakesh K. Pathak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure and biological perspectives of Cu(II)–indomethacin complexes

(2014) Alketa Tarushi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

A Breast Cancer Stem Cell-Selective, Mammospheres-Potent Osmium(VI) Nitrido Complex

(2014) Kogularamanan Suntharalingam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Advances in Copper Complexes as Anticancer Agents

(2013) Carlo Santini et al.   CHEMICAL REVIEWS

Quinolones and non-steroidal anti-inflammatory drugs interacting with copper(ii), nickel(ii), cobalt(ii) and zinc(ii): structural features, biological evaluation and perspectives

(2013) George Psomas et al.   DALTON TRANSACTIONS

Expression of Cox-2 in human breast cancer cells as a critical determinant of epithelial-to-mesenchymal transition and invasiveness

(2013) Claudia Bocca et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Nonsteroidal anti-inflammatory drugs suppress cancer stem cellsviainhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer

(2013) Chang Mo Moon et al.   INTERNATIONAL JOURNAL OF CANCER

Copper(II) interacting with the non-steroidal antiinflammatory drug flufenamic acid: Structure, antioxidant activity and binding to DNA and albumins

(2013) Charikleia Tolia et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Copper Complexes as Anticancer Agents

(2012) Cristina Marzano et al.   Anti-Cancer Agents in Medicinal Chemistry

Reactive Oxygen Species in Cancer Stem Cells

(2012) Xiaoke Shi et al.   ANTIOXIDANTS & REDOX SIGNALING

Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells

(2012) P Liu et al.   BRITISH JOURNAL OF CANCER

Identification of inhibitors of ovarian cancer stem-like cells by high-throughput screening

(2012) Roman Mezencev et al.   Journal of Ovarian Research

Copper: An essential metal in biology

(2011) Richard A. Festa et al.   CURRENT BIOLOGY

Non-steroidal antiinflammatory drug–copper(ii) complexes: Structure and biological perspectives

(2011) Filitsa Dimiza et al.   DALTON TRANSACTIONS

Non-steroidal anti-inflammatory drug diflunisal interacting with Cu(II). Structure and biological features

(2011) Stella Fountoulaki et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Interaction of copper(II) with the non-steroidal anti-inflammatory drugs naproxen and diclofenac: Synthesis, structure, DNA- and albumin-binding

(2010) Filitsa Dimiza et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Role of COX-2 in Tumorospheres Derived from a Breast Cancer Cell Line

(2010) Balraj Singh et al.   JOURNAL OF SURGICAL RESEARCH

Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics

(2010) Anna Maria Calcagno et al.   JNCI-Journal of the National Cancer Institute

Targeting breast cancer stem cells

(2010) Sean P. McDermott et al.   Molecular Oncology

A mammalian functional-genetic approach to characterizing cancer therapeutics

(2010) Hai Jiang et al.   Nature Chemical Biology

Modulation of the Biological Properties of Aspirin by Formation of a Bioorganometallic Derivative

(2009) Ingo Ott et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Cancer stem cells: mirage or reality?

(2009) Piyush B Gupta et al.   NATURE MEDICINE

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL