IL-4 together with IL-1β induces antitumor Th9 cell differentiation in the absence of TGF-β signaling

Th9 Cells Represent a Unique Subset of CD4 + T Cells Endowed with the Ability to Eradicate Advanced Tumors

(2018) Yong Lu et al.   CANCER CELL

Cholesterol negatively regulates IL-9–producing CD8+T cell differentiation and antitumor activity

(2018) Xingzhe Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Foxo1 and Foxp1 play opposing roles in regulating the differentiation and antitumor activity of TH9 cells programmed by IL-7

(2017) Enguang Bi et al.   Science Signaling

Foxo1 and Foxp1 play opposing roles in regulating the differentiation and antitumor activity of TH9 cells programmed by IL-7

(2017) Enguang Bi et al.   Science Signaling

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Histone Deacetylase SIRT1 Negatively Regulates the Differentiation of Interleukin-9-Producing CD4 + T Cells

(2016) Yu Wang et al.   IMMUNITY

Peripheral blood Th9 cells are a possible pharmacodynamic biomarker of nivolumab treatment efficacy in metastatic melanoma patients

(2016) Yumi Nonomura et al.   OncoImmunology

The DNA-binding inhibitor Id3 regulates IL-9 production in CD4+ T cells

(2015) Hiroko Nakatsukasa et al.   NATURE IMMUNOLOGY

Glucocorticoid-induced tumor necrosis factor receptor–related protein co-stimulation facilitates tumor regression by inducing IL-9–producing helper T cells

(2015) Il-Kyu Kim et al.   NATURE MEDICINE

GITR subverts Foxp3+ Tregs to boost Th9 immunity through regulation of histone acetylation

(2015) Xiang Xiao et al.   Nature Communications

Murine Th9 cells promote the survival of myeloid dendritic cells in cancer immunotherapy

(2014) Jungsun Park et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Role of TGF-β Signaling in Generation of CD39+CD73+Myeloid Cells in Tumors

(2014) Sergey V. Ryzhov et al.   JOURNAL OF IMMUNOLOGY

The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells

(2014) Frédérique Végran et al.   NATURE IMMUNOLOGY

Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression

(2014) Wei Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of NF-κB by TNF family cytokines

(2014) Matthew S. Hayden et al.   SEMINARS IN IMMUNOLOGY

Characterization of T-Bet and Eomes in Peripheral Human Immune Cells

(2014) James J. Knox et al.   Frontiers in Immunology

Th9 cell development requires a BATF-regulated transcriptional network

(2013) Rukhsana Jabeen et al.   JOURNAL OF CLINICAL INVESTIGATION

Utilizing TH9 cells as a novel therapeutic strategy for malignancies

(2013) Yong Lu et al.   OncoImmunology

Activin A and TGF-β promote TH9 cell–mediated pulmonary allergic pathology

(2012) Carla P. Jones et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Th9 cells promote antitumor immune responses in vivo

(2012) Yong Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: In the Absence of TGF-  Signaling in T Cells, Fewer CD103+ Regulatory T Cells Develop, but Exuberant IFN-  Production Renders Mice More Susceptible to Helminth Infection

(2012) L. A. Reynolds et al.   JOURNAL OF IMMUNOLOGY

Inflammasome-Derived IL-1  Regulates the Production of GM-CSF by CD4+ T Cells and    T Cells

(2012) J. R. Lukens et al.   JOURNAL OF IMMUNOLOGY

The Tick Salivary Protein Sialostatin L Inhibits the Th9-Derived Production of the Asthma-Promoting Cytokine IL-9 and Is Effective in the Prevention of Experimental Asthma

(2012) H. Horka et al.   JOURNAL OF IMMUNOLOGY

OX40 signaling favors the induction of TH9 cells and airway inflammation

(2012) Xiang Xiao et al.   NATURE IMMUNOLOGY

VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R

(2011) Hanbo Chen et al.   BMC BIOINFORMATICS

Generation of anti-inflammatory adenosine byleukocytes is regulated by TGF-β

(2011) Frederico S. Regateiro et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

STAT6-Dependent Regulation of Th9 Development

(2011) R. Goswami et al.   JOURNAL OF IMMUNOLOGY

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells

(2010) Valérie Staudt et al.   IMMUNITY

Regulation of human Th9 differentiation by type I interferons and IL-21

(2010) Michael T Wong et al.   IMMUNOLOGY AND CELL BIOLOGY

Regulation of IL-9 expression by IL-25 signaling

(2010) Pornpimon Angkasekwinai et al.   NATURE IMMUNOLOGY

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation

(2010) Hua-Chen Chang et al.   NATURE IMMUNOLOGY

Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes

(2009) A. Jager et al.   JOURNAL OF IMMUNOLOGY

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY