ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail

KNL1 Binding to PP1 and Microtubules Is Mutually Exclusive

(2018) Rakhi Bajaj et al.   STRUCTURE

YAP/TAZ as therapeutic targets in cancer

(2016) Francesca Zanconato et al.   CURRENT OPINION IN PHARMACOLOGY

A genome-wide resource for the analysis of protein localisation in Drosophila

(2016) Mihail Sarov et al.   eLife

The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism

(2016) Ganesan Senthil Kumar et al.   eLife

The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly

(2015) Yuanyuan Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Strategies to make protein serine/threonine (PP1, calcineurin) and tyrosine phosphatases (PTP1B) druggable: Achieving specificity by targeting substrate and regulatory protein interaction sites

(2015) Wolfgang Peti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Drosophila MAGI interacts with RASSF8 to regulate E-Cadherin-based adherens junctions in the developing eye

(2015) S. Zaessinger et al.   DEVELOPMENT

Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits

(2015) Toon Verheyen et al.   NUCLEIC ACIDS RESEARCH

Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase

(2015) Meng S. Choy et al.   Cell Reports

G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases

(2015) Ruming Chen et al.   eLife

Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library

(2014) N. Lowe et al.   DEVELOPMENT

Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos

(2014) C. M. Lye et al.   DEVELOPMENT

ASPP2 Links the Apical Lateral Polarity Complex to the Regulation of YAP Activity in Epithelial Cells

(2014) Christophe Royer et al.   PLoS One

Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code

(2014) M. S. Choy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein phosphatase 1 catalytic isoforms: specificity toward interacting proteins

(2014) Luís Korrodi-Gregório et al.   Translational Research

Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery

(2014) Daniel G Booth et al.   eLife

Decision making inxia2

(2013) Graeme Winter et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A versatile platform for creating a comprehensive UAS-ORFeome library in Drosophila

(2013) J. Bischof et al.   DEVELOPMENT

Polyproline-II Helix in Proteins: Structure and Function

(2013) Alexei A. Adzhubei et al.   JOURNAL OF MOLECULAR BIOLOGY

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1

(2013) Simon Hauri et al.   Molecular Systems Biology

The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin

(2013) Simina Grigoriu et al.   PLOS BIOLOGY

Challenges and Opportunities in the Development of Protein Phosphatase-Directed Therapeutics

(2012) Sofie De Munter et al.   ACS Chemical Biology

Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins

(2012) Tamara D. Skene-Arnold et al.   BIOCHEMICAL JOURNAL

Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention

(2012) Pavel Tsaytler et al.   FEBS Journal

Structural basis for protein phosphatase 1 regulation and specificity

(2012) Wolfgang Peti et al.   FEBS Journal

The PP1 binding code: a molecular-lego strategy that governs specificity

(2012) Ewald Heroes et al.   FEBS Journal

SH3 domain ligand binding: What's the consensus and where's the specificity?

(2012) Kalle Saksela et al.   FEBS LETTERS

Structural Basis for ASPP2 Recognition by the Tumor Suppressor p73

(2012) Peter Canning et al.   JOURNAL OF MOLECULAR BIOLOGY

The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme

(2012) Nichole O'Connell et al.   STRUCTURE

Inhibitory Member of the Apoptosis-stimulating Proteins of the p53 Family (iASPP) Interacts with Protein Phosphatase 1 via a Noncanonical Binding Motif

(2011) Susana Llanos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis

(2010) Asha Recino et al.   BIOCHEMICAL JOURNAL

ASPP2 Regulates Epithelial Cell Polarity through the PAR Complex

(2010) Weili Cong et al.   CURRENT BIOLOGY

ASPP2 Binds Par-3 and Controls the Polarity and Proliferation of Neural Progenitors during CNS Development

(2010) Roberta Sottocornola et al.   DEVELOPMENTAL CELL

PP1 Cooperates with ASPP2 to Dephosphorylate and Activate TAZ

(2010) Chen-Ying Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

(2010) Michael J Ragusa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The extended PP1 toolkit: designed to create specificity

(2010) Mathieu Bollen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Docking Motif-Guided Mapping of the Interactome of Protein Phosphatase-1

(2009) Annick Hendrickx et al.   CHEMISTRY & BIOLOGY

The dASPP-dRASSF8 Complex Regulates Cell-Cell Adhesion during Drosophila Retinal Morphogenesis

(2009) Paul F. Langton et al.   CURRENT BIOLOGY

Basis for the Isoform-specific Interaction of Myosin Phosphatase Subunits Protein Phosphatase 1c β and Myosin Phosphatase Targeting Subunit 1

(2009) Elizabeth Scotto-Lavino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

From Promiscuity to Precision: Protein Phosphatases Get a Makeover

(2009) David M. Virshup et al.   MOLECULAR CELL

An integrated workflow for charting the human interaction proteome: insights into the PP2A system

(2009) Timo Glatter et al.   Molecular Systems Biology

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Selective targeting of the γ1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin

(2008) Leigh C. Carmody et al.   FASEB JOURNAL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY