Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code

MicroRNA-34a regulates cardiac ageing and function

(2013) Reinier A. Boon et al.   NATURE

The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin

(2013) Simina Grigoriu et al.   PLOS BIOLOGY

PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth

(2013) Anita Ciurciu et al.   PLoS Genetics

Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins

(2012) Tamara D. Skene-Arnold et al.   BIOCHEMICAL JOURNAL

Regulation of protein phosphatase 1 by intrinsically disordered proteins

(2012) Meng S. Choy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Structural basis for protein phosphatase 1 regulation and specificity

(2012) Wolfgang Peti et al.   FEBS Journal

The PP1 binding code: a molecular-lego strategy that governs specificity

(2012) Ewald Heroes et al.   FEBS Journal

NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes

(2012) Nikki Minnebo et al.   NUCLEIC ACIDS RESEARCH

The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme

(2012) Nichole O'Connell et al.   STRUCTURE

Downregulation of the Phosphatase Nuclear Targeting Subunit (PNUTS) triggers pRB dephosphorylation and apoptosis in pRB positive tumor cell lines

(2010) Xavier Graña   CANCER BIOLOGY & THERAPY

Reduced expression of PNUTS leads to activation of Rb-phosphatase and caspase-mediated apoptosis

(2010) Gabriel De Leon et al.   CANCER BIOLOGY & THERAPY

The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response

(2010) Helga B Landsverk et al.   EMBO REPORTS

Flexibility in the PP1:spinophilin holoenzyme

(2010) Michael J. Ragusa et al.   FEBS LETTERS

Structural Signature of the MYPT1−PP1 Interaction

(2010) Anderson S. Pinheiro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mass spectrometry and biochemical analysis of RNA polymerase II: targeting by protein phosphatase-1

(2010) Marina Jerebtsova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

(2010) Michael J Ragusa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein

(2010) Alexander Hirschi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Diversity in Free and Bound States of Intrinsically Disordered Protein Phosphatase 1 Regulators

(2010) Joseph A. Marsh et al.   STRUCTURE

The extended PP1 toolkit: designed to create specificity

(2010) Mathieu Bollen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Detailed Structural Characterization of Unbound Protein Phosphatase 1 Inhibitors†

(2008) Barbara Dancheck et al.   BIOCHEMISTRY