Stereoselective Organocatalyzed Synthesis of α-Fluorinated β-Amino Thioesters and Their Application in Peptide Synthesis

An Enantio- and Diastereoselective Chemoenzymatic Synthesis of α-Fluoro β-Hydroxy Carboxylic Esters

(2016) James K. Howard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective aldol reactions with masked fluoroacetates

(2016) Jakub Saadi et al.   Nature Chemistry

Stereoselective Organocatalytic Synthesis of Oxindoles with Adjacent Tetrasubstituted Stereocenters

(2015) Oliver D. Engl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

Peptide therapeutics: Targeting the undruggable space

(2015) Natia Tsomaia   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Diastereoselective Addition of Metal α-Fluoroenolates of Carboxylate Esters to N-tert-Butylsulfinyl Imines: Synthesis of α-Fluoro-β-amino Acids

(2015) Huaqi Shang et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Construction of Vicinal Tetrasubstituted Stereocenters by the Mannich Reaction of Linear α-Substituted Monothiomalonates with Isatin N-Boc Ketimines

(2015) Teng Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Catalytic Asymmetric Mannich-Type Reaction of α- and β-Fluorinated Amides

(2015) Lennart Brewitz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric synthesis of syn-propargylamines and unsaturated β-amino acids under Brønsted base catalysis

(2015) Yingcheng Wang et al.   Nature Communications

Stereoselective Metal-Free Synthesis of β-Amino Thioesters with Tertiary and Quaternary Stereogenic Centers

(2014) Annette Bahlinger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Dual-Reagent Catalysis: Mannich-type Reactions Catalyzed by Ion Pair

(2014) Hong-Yu Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Stereoselective Synthesis of Acyclic γ-Nitrothioesters with All-Carbon Quaternary Stereogenic Centers

(2014) Yukihiro Arakawa et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereoselective Synthesis of Indolines via Organocatalytic Thioester Enolate Addition Reactions

(2014) Andrej Kolarovic et al.   ORGANIC LETTERS

Organocatalytic Route to Dihydrocoumarins and Dihydroquinolinones in All Stereochemical Configurations

(2014) Oliver D. Engl et al.   ORGANIC LETTERS

Synthesis, Structure, and Biological Applications ofα-Fluorinatedβ-Amino Acids and Derivatives

(2012) Taryn L. March et al.   CHEMISTRY & BIODIVERSITY

Synthesis and Conformation of Fluorinated β-Peptidic Compounds

(2012) Victoria Peddie et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Synthesis of AG-041R by using N-Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts

(2012) Noriyuki Hara et al.   CHEMISTRY-A EUROPEAN JOURNAL

Therapeutic peptides

(2012) Fernando Albericio et al.   Future Medicinal Chemistry

Fluorinated amino acids: compatibility with native protein structures and effects on protein–protein interactions

(2011) Mario Salwiczek et al.   CHEMICAL SOCIETY REVIEWS

Expanding the Utility of Brønsted Base Catalysis: Biomimetic Enantioselective Decarboxylative Reactions

(2011) Yuanhang Pan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Note: Helix or No Helix of β-Peptides Containing β3hAla(αF) Residues?

(2011) Bernhard Jaun et al.   HELVETICA CHIMICA ACTA

Stereoselective Preparation of 3-Amino-2-fluoro Carboxylic Acid Derivatives, and Their Incorporation in Tetrahydropyrimidin-4(1H)-ones, and in Open-Chain and Cyclic β-Peptides

(2011) Tomohiro Yoshinari et al.   HELVETICA CHIMICA ACTA

Mono thiomalonates as thioester enolate equivalents—enantioselective 1,4-addition reactions to nitroolefins under mild conditions

(2011) Paolo Clerici et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chiral Phosphoric Acid Catalyzed Enantioselective Synthesis of β-Amino-α,α-difluoro Carbonyl Compounds

(2011) Wataru Kashikura et al.   ORGANIC LETTERS

Catalytic asymmetric Mannich-type reactions of fluorinated ketoesters with N-Boc aldimines in the presence of chiral palladium complexes

(2011) Young Ku Kang et al.   TETRAHEDRON LETTERS

Enantioselective Synthesis of α-Fluoro-β3-amino Esters: Synthesis of Enantiopure, Orthogonally Protected α-Fluoro-β3-lysine

(2010) Peter J. Duggan et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Enantioselective Olefin Aminofluorination

(2010) Chandrakumar Appayee et al.   ORGANIC LETTERS

Asymmetric Mannich Reaction of Fluorinated Ketoesters with a Tryptophan-Derived Bifunctional Thiourea Catalyst

(2009) Xiao Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of α-Fluorinated β-Amino Acid Derivatives by an Asymmetric Mannich Reaction and Selective Deacylation/Decarboxylation Reactions

(2009) Yuanhang Pan et al.   CHEMISTRY-A EUROPEAN JOURNAL

β-Peptidic Peptidomimetics

(2008) Dieter Seebach et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chemoselective Ligation and Modification Strategies for Peptides and Proteins

(2008) Christian P. R. Hackenberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Squaramide Derivatives are Excellent Hydrogen Bond Donor Catalysts

(2008) Jeremiah P. Malerich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS