A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics

Site-Specific Polymer Conjugation Stabilizes Therapeutic Enzymes in the Gastrointestinal Tract

(2015) Jessica D. Schulz et al.   ADVANCED MATERIALS

Biopharmaceutical benchmarks 2014

(2014) Gary Walsh   NATURE BIOTECHNOLOGY

Semi-permeable coatings fabricated from comb-polymers efficiently protect proteins in vivo

(2014) Mi Liu et al.   Nature Communications

Growing polymers from peptides and proteins: a biomedical perspective

(2013) Yizhi Qi et al.   Polymer Chemistry

Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control

(2013) M. Amiram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Site-Specific PEGylated Exendin-4 Modified with a High Molecular Weight Trimeric PEG Reduces Steric Hindrance and Increases Type 2 Antidiabetic Therapeutic Effects

(2012) Tae Hyung Kim et al.   BIOCONJUGATE CHEMISTRY

Discovery and development of exenatide: the first antidiabetic agent to leverage the multiple benefits of the incretin hormone, GLP-1

(2012) David G Parkes et al.   Expert Opinion on Drug Discovery

Emerging synthetic approaches for protein–polymer conjugations

(2011) Rebecca M. Broyer et al.   CHEMICAL COMMUNICATIONS

PEGylation improves pharmacokinetic profile, liver uptake and efficacy of Interferon gamma in liver fibrosis

(2011) Ruchi Bansal et al.   JOURNAL OF CONTROLLED RELEASE

Poly(zwitterionic)protein conjugates offer increased stability without sacrificing binding affinity or bioactivity

(2011) Andrew J. Keefe et al.   Nature Chemistry

Proteins as Initiators of Controlled Radical Polymerization: Grafting-from via ATRP and RAFT

(2011) Brent S. Sumerlin   ACS Macro Letters

Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications

(2010) Jeremiah A Johnson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Recent advances in the design of bioconjugates from controlled/living radical polymerization

(2010) Benjamin Le Droumaguet et al.   Polymer Chemistry

Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition

(2009) Marjoke F. Debets et al.   CHEMICAL COMMUNICATIONS

Poly(2-methacryloyloxyethyl phosphorylcholine) for Protein Conjugation

(2008) Andrew Lewis et al.   BIOCONJUGATE CHEMISTRY

Peptide/protein–polymer conjugates: synthetic strategies and design concepts

(2008) Marc A. Gauthier et al.   CHEMICAL COMMUNICATIONS

Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of Exenatide in Japanese Patients With Type 2 Diabetes Mellitus

(2008) Prajakti A. Kothare et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Protein therapeutics: a summary and pharmacological classification

(2007) Benjamin Leader et al.   NATURE REVIEWS DRUG DISCOVERY