The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells

An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance

(2018) Assaf C. Bester et al.   CELL

The Long Noncoding RNA TP73-AS1 Interacted with miR-124 to Modulate Glioma Growth by Targeting Inhibitor of Apoptosis-Stimulating Protein of p53

(2018) Shuai Xiao et al.   DNA AND CELL BIOLOGY

Temozolomide-induced increase of tumorigenicity can be diminished by targeting of mitochondria in in vitro models of patient individual glioblastoma

(2018) Doreen William et al.   PLoS One

Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators

(2017) Harry Bulstrode et al.   GENES & DEVELOPMENT

Differential Functional Roles of ALDH1A1 and ALDH1A3 in Mediating Metastatic Behavior and Therapy Resistance of Human Breast Cancer Cells

(2017) Alysha Croker et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Long Non-Coding RNA TP73-AS1 Interacted With miR-142 to Modulate Brain Glioma Growth Through HMGB1/RAGE Pathway

(2017) Rong Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Role of AHR and HIF-1α in Glioblastoma Metabolism

(2017) Galina Gabriely et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Long Noncoding RNAs in Cancer Pathways

(2016) Adam M. Schmitt et al.   CANCER CELL

Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines

(2016) Radosſaw Januchowski et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

An ID2-dependent mechanism for VHL inactivation in cancer

(2016) Sang Bae Lee et al.   NATURE

Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development

(2016) Kelly M. Anderson et al.   NATURE

Local regulation of gene expression by lncRNA promoters, transcription and splicing

(2016) Jesse M. Engreitz et al.   NATURE

Advances in the molecular genetics of gliomas — implications for classification and therapy

(2016) Guido Reifenberger et al.   Nature Reviews Clinical Oncology

Enhancers as non-coding RNA transcription units: recent insights and future perspectives

(2016) Wenbo Li et al.   NATURE REVIEWS GENETICS

p73 promotes glioblastoma cell invasion by directly activating POSTN (periostin) expression

(2016) Vivien Landré et al.   Oncotarget

Aldehyde dehydrogenase 1A1 in stem cells and cancer

(2016) Hiroyuki Tomita et al.   Oncotarget

The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches

(2016) Marco Mineo et al.   Cell Reports

Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation

(2016) Sophia M Blake et al.   eLife

Cancer stem cells in glioblastoma

(2015) Justin D. Lathia et al.   GENES & DEVELOPMENT

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

Glioblastoma Stem Cells Respond to Differentiation Cues but Fail to Undergo Commitment and Terminal Cell-Cycle Arrest

(2015) Helena Carén et al.   Stem Cell Reports

The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation

(2014) D. Raha et al.   CANCER RESEARCH

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

(2014) Luke A. Gilbert et al.   CELL

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

(2014) Mario L. Suvà et al.   CELL

The evolution of lncRNA repertoires and expression patterns in tetrapods

(2014) Anamaria Necsulea et al.   NATURE

HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response

(2014) B. Rotblat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells

(2013) N. A. Kearns et al.   DEVELOPMENT

Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A

(2013) C. G. Hubert et al.   GENES & DEVELOPMENT

Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner

(2013) S. H. Stricker et al.   GENES & DEVELOPMENT

Long non-coding RNAs: new players in cell differentiation and development

(2013) Alessandro Fatica et al.   NATURE REVIEWS GENETICS

A long non-coding RNA signature in glioblastoma multiforme predicts survival

(2013) Xiao-Qin Zhang et al.   NEUROBIOLOGY OF DISEASE

TAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptor

(2013) M. V. Niklison-Chirou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells

(2013) A. A. Sigova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

(2012) Pierre Bady et al.   ACTA NEUROPATHOLOGICA

Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells

(2012) P Liu et al.   BRITISH JOURNAL OF CANCER

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

(2012) Dominik Sturm et al.   CANCER CELL

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Aldehyde dehydrogenase 1A1—a new mediator of resistance to temozolomide in glioblastoma

(2012) Andrea Schäfer et al.   NEURO-ONCOLOGY

Chemoresistance of glioblastoma cancer stem cells - much more complex than expected

(2011) Dagmar Beier et al.   Molecular Cancer

Metabolic state of glioma stem cells and nontumorigenic cells

(2011) E. Vlashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long noncoding RNAs and human disease

(2011) Orly Wapinski et al.   TRENDS IN CELL BIOLOGY

p73 regulates maintenance of neural stem cell

(2010) Massimiliano Agostini et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

KIAA0495/PDAM Is Frequently Downregulated in Oligodendroglial Tumors and Its Knockdown by siRNA Induces Cisplatin Resistance in Glioma Cells

(2010) Jesse Chung-Sean Pang et al.   BRAIN PATHOLOGY

TAp73 Acts via the bHLH Hey2 to Promote Long-Term Maintenance of Neural Precursors

(2010) Masashi Fujitani et al.   CURRENT BIOLOGY

Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity

(2010) M. Rasper et al.   NEURO-ONCOLOGY

Interaction of Hypoxia-Inducible Factor-1α and Notch Signaling Regulates Medulloblastoma Precursor Proliferation and Fate

(2010) Francesca Pistollato et al.   STEM CELLS

p63 and p73, the Ancestors of p53

(2010) V. Dotsch et al.   Cold Spring Harbor Perspectives in Biology

Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens

(2009) Steven M. Pollard et al.   Cell Stem Cell

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

Survival of the Fittest: Cancer Stem Cells in Therapeutic Resistance and Angiogenesis

(2008) Christine E. Eyler et al.   JOURNAL OF CLINICAL ONCOLOGY