Back to the Future for Influenza Preimmunity—Looking Back at Influenza Virus History to Infer the Outcome of Future Infections

Imprinting of Repeated Influenza A/H3 Exposures on Antibody Quantity and Antibody Quality: Implications on Seasonal Vaccine Strain Selection and Vaccine Performance

(2018) Martina Kosikova et al.   CLINICAL INFECTIOUS DISEASES

From Original Antigenic Sin to the Universal Influenza Virus Vaccine

(2018) Carole Henry et al.   TRENDS IN IMMUNOLOGY

Host Immune Response to Influenza A Virus Infection

(2018) Xiaoyong Chen et al.   Frontiers in Immunology

Influenza Vaccine Effectiveness in Preventing Influenza-associated Hospitalizations During Pregnancy: A Multi-country Retrospective Test Negative Design Study, 2010–2016

(2018) Mark G Thompson et al.   CLINICAL INFECTIOUS DISEASES

Vaccine Effectiveness Against Lineage-matched and -mismatched Influenza B Viruses Across 8 Seasons in Canada, 2010–2011 to 2017–2018

(2018) Danuta M Skowronski et al.   CLINICAL INFECTIOUS DISEASES

Serial Vaccination and the Antigenic Distance Hypothesis: Effects on Influenza Vaccine Effectiveness During A(H3N2) Epidemics in Canada, 2010–2011 to 2014–2015

(2017) Danuta M. Skowronski et al.   JOURNAL OF INFECTIOUS DISEASES

The Doctrine of Original Antigenic Sin: Separating Good From Evil

(2017) Arnold S. Monto et al.   JOURNAL OF INFECTIOUS DISEASES

Why is the flu vaccine so mediocre?

(2017) Jon Cohen   SCIENCE

Immune history and influenza virus susceptibility

(2017) Sarah Cobey et al.   Current Opinion in Virology

Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes

(2016) Nicole L. Kallewaard et al.   CELL

Heads, stalks and everything else: how can antibodies eradicate influenza as a human disease?

(2016) Karlynn E Neu et al.   CURRENT OPINION IN IMMUNOLOGY

Taking the Broad View on B Cell Affinity Maturation

(2016) Karlynn E. Neu et al.   IMMUNITY

Consecutive Infections With Influenza A and B Virus in Children During the 2014–2015 Seasonal Influenza Epidemic

(2016) Johannes Möst et al.   JOURNAL OF INFECTIOUS DISEASES

Antigenic Fingerprinting of Antibody Response in Humans following Exposure to Highly Pathogenic H7N7 Avian Influenza Virus: Evidence for Anti-PA-X Antibodies

(2016) Surender Khurana et al.   JOURNAL OF VIROLOGY

Global epidemiology of avian influenza A H5N1 virus infection in humans, 1997–2015: a systematic review of individual case data

(2016) Shengjie Lai et al.   LANCET INFECTIOUS DISEASES

Potent protection against H5N1 and H7N9 influenza via childhood hemagglutinin imprinting

(2016) Katelyn M. Gostic et al.   SCIENCE

Human influenza viruses and CD8 + T cell responses

(2016) Emma J Grant et al.   Current Opinion in Virology

Antibodies with ‘Original Antigenic Sin’ Properties Are Valuable Components of Secondary Immune Responses to Influenza Viruses

(2016) Susanne L. Linderman et al.   PLoS Pathogens

Sterilizing immunity to influenza virus infection requires local antigen-specific T cell response in the lungs

(2016) Avijit Dutta et al.   Scientific Reports

Sequential Infection in Ferrets with Antigenically Distinct Seasonal H1N1 Influenza Viruses Boosts Hemagglutinin Stalk-Specific Antibodies

(2015) Greg A. Kirchenbaum et al.   JOURNAL OF VIROLOGY

Correlation between Virus Replication and Antibody Responses in Macaques following Infection with Pandemic Influenza A Virus

(2015) Gerrit Koopman et al.   JOURNAL OF VIROLOGY

Hemagglutinin Stalk Immunity Reduces Influenza Virus Replication and Transmission in Ferrets

(2015) Raffael Nachbagauer et al.   JOURNAL OF VIROLOGY

Advances in the development of influenza virus vaccines

(2015) Florian Krammer et al.   NATURE REVIEWS DRUG DISCOVERY

Immune history profoundly affects broadly protective B cell responses to influenza

(2015) Sarah F. Andrews et al.   Science Translational Medicine

Innate Immunity and the Inter-exposure Interval Determine the Dynamics of Secondary Influenza Virus Infection and Explain Observed Viral Hierarchies

(2015) Pengxing Cao et al.   PLoS Computational Biology

Influenza Transmission in the Mother-Infant Dyad Leads to Severe Disease, Mammary Gland Infection, and Pathogenesis by Regulating Host Responses

(2015) Stéphane G. Paquette et al.   PLoS Pathogens

Rates and determinants of seasonal influenza vaccination in pregnancy and association with neonatal outcomes

(2014) A. Legge et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Pathogenic influenza B virus in the ferret model establishes lower respiratory tract infection

(2014) S. S. H. Huang et al.   JOURNAL OF GENERAL VIROLOGY

Induction of Broadly Reactive Anti-Hemagglutinin Stalk Antibodies by an H5N1 Vaccine in Humans

(2014) R. Nachbagauer et al.   JOURNAL OF VIROLOGY

Characterization of a Broadly Neutralizing Monoclonal Antibody That Targets the Fusion Domain of Group 2 Influenza A Virus Hemagglutinin

(2014) G. S. Tan et al.   JOURNAL OF VIROLOGY

Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus

(2014) M. Worobey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody landscapes after influenza virus infection or vaccination

(2014) J. M. Fonville et al.   SCIENCE

Impaired heterologous immunity in aged ferrets during sequential influenza A H1N1 infection

(2014) Stéphane G. Paquette et al.   VIROLOGY

Immunogenicity and Reactogenicity of an Inactivated Quadrivalent Influenza Vaccine Administered Intramuscularly to Children 6 to 35 Months of Age in 2012–2013: A Randomized, Double-Blind, Controlled, Multicenter, Multicountry, Clinical Trial

(2014) Joanne M. Langley et al.   Journal of the Pediatric Infectious Diseases Society

The evolving history of influenza viruses and influenza vaccines

(2013) Claude Hannoun   Expert Review of Vaccines

Immune history shapes specificity of pandemic H1N1 influenza antibody responses

(2013) Yang Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Memory B Cells in Mouse Models

(2013) B. Bergmann et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Neutralizing Antibodies Against Previously Encountered Influenza Virus Strains Increase over Time: A Longitudinal Analysis

(2013) M. S. Miller et al.   Science Translational Medicine

Visualizing influenza virus infection in living mice

(2013) Weiqi Pan et al.   Nature Communications

Role of T cell immunity in recovery from influenza virus infection

(2013) Jie Sun et al.   Current Opinion in Virology

Influenza virus hemagglutinin stalk-based antibodies and vaccines

(2013) Florian Krammer et al.   Current Opinion in Virology

A randomized, controlled non-inferiority trial comparing A(H1N1)pmd09 vaccine antigen, with and without AS03 adjuvant system, co-administered or sequentially administered with an inactivated trivalent seasonal influenza vaccine

(2012) Joanne M Langley et al.   BMC INFECTIOUS DISEASES

Differential Pathological and Immune Responses in Newly Weaned Ferrets Are Associated with a Mild Clinical Outcome of Pandemic 2009 H1N1 Infection

(2012) S. S. H. Huang et al.   JOURNAL OF VIROLOGY

Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice

(2012) F. Krammer et al.   JOURNAL OF VIROLOGY

Sequencing, Annotation, and Characterization of the Influenza Ferret Infectome

(2012) A. J. Leon et al.   JOURNAL OF VIROLOGY

Neonatal Plasma Polarizes TLR4-Mediated Cytokine Responses towards Low IL-12p70 and High IL-10 Production via Distinct Factors

(2012) Mirjam E. Belderbos et al.   PLoS One

Phylogenetic and Evolutionary History of Influenza B Viruses, which Caused a Large Epidemic in 2011–2012, Taiwan

(2012) Ji-Rong Yang et al.   PLoS One

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

(2012) N. Pica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cells and influenza A virus infection

(2012) Jason Waithman et al.   Virulence

Evidence for Antigenic Seniority in Influenza A (H3N2) Antibody Responses in Southern China

(2012) Justin Lessler et al.   PLoS Pathogens

Re-Engaging Cross-Reactive Memory B Cells: The Influenza Puzzle

(2012) Ali H. Ellebedy et al.   Frontiers in Immunology

Influenza-induced innate immunity: regulators of viral replication, respiratory tract pathology & adaptive immunity

(2011) Karen L Oslund et al.   Future Virology

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

Contributions of Antinucleoprotein IgG to Heterosubtypic Immunity against Influenza Virus

(2011) Mark W. LaMere et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells and CD28 Costimulation Are Required To Sustain Virus-Specific CD8+ T Cell Responses during the Effector Phase In Vivo

(2011) D. V. Dolfi et al.   JOURNAL OF IMMUNOLOGY

Seasonal H1N1 Influenza Virus Infection Induces Cross-Protective Pandemic H1N1 Virus Immunity through a CD8-Independent, B Cell-Dependent Mechanism

(2011) Y. Fang et al.   JOURNAL OF VIROLOGY

Histopathological and immunohistochemical findings of 20 autopsy cases with 2009 H1N1 virus infection

(2011) Noriko Nakajima et al.   MODERN PATHOLOGY

The development of inducible bronchus-associated lymphoid tissue depends on IL-17

(2011) Javier Rangel-Moreno et al.   NATURE IMMUNOLOGY

Why Do Influenza Virus Subtypes Die Out? A Hypothesis

(2011) P. Palese et al.   mBio

Immune memory redefined: characterizing the longevity of natural killer cells

(2010) Joseph C. Sun et al.   IMMUNOLOGICAL REVIEWS

Influenza Hemagglutinin and Neuraminidase Membrane Glycoproteins

(2010) Steven J. Gamblin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiviral CD8+T cell effector activities in situ are regulated by target cell type

(2010) Matthew M. Hufford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multiple Infections with Seasonal Influenza A Virus Induce Cross‐Protective Immunity against A(H1N1) Pandemic Influenza Virus in a Ferret Model

(2010) Karen L. Laurie et al.   JOURNAL OF INFECTIOUS DISEASES

Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes

(2010) Ana Clara Monsalvo et al.   NATURE MEDICINE

The Re-Emergence of H1N1 Influenza Virus in 1977: A Cautionary Tale for Estimating Divergence Times Using Biologically Unrealistic Sampling Dates

(2010) Joel O. Wertheim   PLoS One

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

(2010) B. Manicassamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seasonal influenza and vaccination coverage

(2010) Arnold S. Monto   VACCINE

Modeling host responses in ferrets during A/California/07/2009 influenza infection

(2010) Thomas Rowe et al.   VIROLOGY

Memory B cells: Effectors of long-lived immune responses

(2009) Stuart G. Tangye et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-10 Deficiency Unleashes an Influenza-Specific Th17 Response and Enhances Survival against High-Dose Challenge

(2009) K. K. McKinstry et al.   JOURNAL OF IMMUNOLOGY

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10

(2009) Jie Sun et al.   NATURE MEDICINE

Triple-Reassortant Swine Influenza A (H1) in Humans in the United States, 2005–2009

(2009) Vivek Shinde et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cross-Reactive Antibody Responses to the 2009 Pandemic H1N1 Influenza Virus

(2009) Kathy Hancock et al.   NEW ENGLAND JOURNAL OF MEDICINE

Influenza seasonality: Lifting the fog

(2009) M. Lipsitch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dating the emergence of pandemic influenza viruses

(2009) Gavin J. D. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza vaccines

(2009) A.H. Ellebedy et al.   VACCINE

Influenza virus antigenic variation, host antibody production and new approach to control epidemics

(2009) Jiezhong Chen et al.   Virology Journal

The biology of influenza viruses

(2008) Nicole M. Bouvier et al.   VACCINE