An Apoptosis-Inducing Peptidic Heptad That Efficiently Clusters Death Receptor 5

Unexpected hepatotoxicity in a phase I study of TAS266, a novel tetravalent agonistic Nanobody® targeting the DR5 receptor

(2015) Kyriakos P. Papadopoulos et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)

(2015) Franziska Maaß et al.   JOURNAL OF PEPTIDE SCIENCE

Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity

(2014) Jonathan D. Graves et al.   CANCER CELL

Getting TRAIL back on track for cancer therapy

(2014) J Lemke et al.   CELL DEATH AND DIFFERENTIATION

Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction

(2014) Heather A Huet et al.   mAbs

Reprogramming the specificity of sortase enzymes

(2014) Brent M. Dorr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APG350 Induces Superior Clustering of TRAIL Receptors and Shows Therapeutic Antitumor Efficacy Independent of Cross-Linking via Fc  Receptors

(2013) C. Gieffers et al.   MOLECULAR CANCER THERAPEUTICS

Translating TRAIL-receptor targeting agents to the clinic

(2012) Martha W. den Hollander et al.   CANCER LETTERS

Multimerization of an Apoptogenic TRAIL-Mimicking Peptide by Using Adamantane-Based Dendrons

(2012) Giuseppe Lamanna et al.   CHEMISTRY-A EUROPEAN JOURNAL

Arranged Sevenfold: Structural Insights into the C-Terminal Oligomerization Domain of Human C4b-Binding Protein

(2012) Thomas Hofmeyer et al.   JOURNAL OF MOLECULAR BIOLOGY

A general strategy for the evolution of bond-forming enzymes using yeast display

(2011) I. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multivalent DR5 Peptides Activate the TRAIL Death Pathway and Exert Tumoricidal Activity

(2010) V. Pavet et al.   CANCER RESEARCH

Death receptors: Targets for cancer therapy

(2009) Zafar Mahmood et al.   EXPERIMENTAL CELL RESEARCH