A joint study of whole exome sequencing and structural MRI analysis in major depressive disorder

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Mediation analysis for common binary outcomes

(2018) Sheila M. Gaynor et al.   STATISTICS IN MEDICINE

Genome-wide association studies of brain imaging phenotypes in UK Biobank

(2018) Lloyd T. Elliott et al.   NATURE

Common and distinct brain networks underlying verbal and visual creativity

(2017) Wenfeng Zhu et al.   HUMAN BRAIN MAPPING

The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability

(2017) Tarjinder Singh et al.   NATURE GENETICS

Brain grey and white matter predictors of verbal ability traits in older age: The Lothian Birth Cohort 1936

(2017) Paul Hoffman et al.   NEUROIMAGE

Distinct and Shared Endophenotypes of Neural Substrates in Bipolar and Major Depressive Disorders

(2017) Toshio Matsubara et al.   PLoS One

High-Coverage Whole-Exome Sequencing Identifies Candidate Genes for Suicide in Victims with Major Depressive Disorder

(2017) Dóra Tombácz et al.   Scientific Reports

RVTESTS: an efficient and comprehensive tool for rare variant association analysis using sequence data: Table 1.

(2016) Xiaowei Zhan et al.   BIOINFORMATICS

Unexplained Painful Physical Symptoms in Patients with Major Depressive Disorder: Prevalence, Pathophysiology and Management

(2016) Jan Jaracz et al.   CNS DRUGS

Depression as a risk factor for Alzheimer’s disease: Genes, steroids, cytokines and neurogenesis – What do we need to know?

(2016) Joe Herbert et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Theo Vos et al.   LANCET

Erratum: Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms

(2016) N Amin et al.   MOLECULAR PSYCHIATRY

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

(2016) Craig L Hyde et al.   NATURE GENETICS

Brain gray matter alterations in first episodes of depression: A meta-analysis of whole-brain studies

(2016) Huawei Zhang et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Cortical grey matter volume reduction in people with schizophrenia is associated with neuro-inflammation

(2016) Y Zhang et al.   Translational Psychiatry

Changes of grey matter volume in first-episode drug-naive adult major depressive disorder patients with different age-onset

(2016) Zonglin Shen et al.   NeuroImage-Clinical

So depression is an inflammatory disease, but where does the inflammation come from?

(2016) Michael Berk et al.   BMC Medicine

New suggestive genetic loci and biological pathways for attention function in adult attention-deficit/hyperactivity disorder

(2015) Silvia Alemany et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

In pursuit of neuroimaging biomarkers to guide treatment selection in major depressive disorder: a review of the literature

(2015) Marc S. Lener et al.   Annals of the New York Academy of Sciences

Enriched environment decreases microglia and brain macrophages inflammatory phenotypes through adiponectin-dependent mechanisms: Relevance to depressive-like behavior

(2015) Joëlle Chabry et al.   BRAIN BEHAVIOR AND IMMUNITY

Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder

(2015) Kristiina Tammimies et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Decreased insular connectivity in drug-naive major depressive disorder at rest

(2015) Wenbin Guo et al.   JOURNAL OF AFFECTIVE DISORDERS

Erratum: Sex differences in glutamate receptor gene expression in major depression and suicide

(2015) A L Gray et al.   MOLECULAR PSYCHIATRY

Sparse whole-genome sequencing identifies two loci for major depressive disorder

(2015) Na Cai et al.   NATURE

What Twin Studies Tell Us About the Heritability of Brain Development, Morphology, and Function: A Review

(2015) Arija G. Jansen et al.   NEUROPSYCHOLOGY REVIEW

State-dependent and trait-related gray matter changes in nonrefractory depression

(2015) Ling-Li Zeng et al.   NEUROREPORT

High Throughput Sequencing Identifies MicroRNAs Mediating α-Synuclein Toxicity by Targeting Neuroactive-Ligand Receptor Interaction Pathway in Early Stage of Drosophila Parkinson's Disease Model

(2015) Yan Kong et al.   PLoS One

Dissociated large-scale functional connectivity networks of the precuneus in medication-naïve first-episode depression

(2015) Daihui Peng et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Molecular and cellular neuroinflammatory status of mouse brain after systemic lipopolysaccharide challenge: importance of CCR2/CCL2 signaling

(2014) Julie Cazareth et al.   Journal of Neuroinflammation

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission

(2014) T. Karayannis et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia

(2014) S. A. Meda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Anti-inflammatory Treatment on Depression, Depressive Symptoms, and Adverse Effects

(2014) Ole Köhler et al.   JAMA Psychiatry

Substance P receptor antagonist in lateral habenula improves rat depression-like behavior

(2013) Li-Min Yang et al.   BRAIN RESEARCH BULLETIN

Memory outcome after hippocampus sparing resections in the temporal lobe

(2013) K. Wagner et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression

(2013) Anu Tammiste et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

Astrocyte-derived ATP modulates depressive-like behaviors

(2013) Xiong Cao et al.   NATURE MEDICINE

Neuropsychological Deficits in Mice Depleted of the Schizophrenia Susceptibility Gene CSMD1

(2013) Vidar M. Steen et al.   PLoS One

Detecting and Estimating Contamination of Human DNA Samples in Sequencing and Array-Based Genotype Data

(2012) Goo Jun et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-Wide Association Study of Multiplex Schizophrenia Pedigrees

(2012) Douglas F. Levinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

Systematic review of the neural basis of social cognition in patients with mood disorders

(2012) Andrée Cusi et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

A mega-analysis of genome-wide association studies for major depressive disorder

(2012)   MOLECULAR PSYCHIATRY

Multifaceted genomic risk for brain function in schizophrenia

(2012) Jiayu Chen et al.   NEUROIMAGE

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Alzheimer's disease risk factor complement receptor 1 is associated with depression

(2012) Gillian Hamilton et al.   NEUROSCIENCE LETTERS

Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development

(2012) G. R. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic plasticity in depression: Molecular, cellular and functional correlates

(2012) W.N. Marsden   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

CNTNAP2 is significantly associated with schizophrenia and major depression in the Han Chinese population

(2012) Weidong Ji et al.   PSYCHIATRY RESEARCH

Gray matter volume in major depressive disorder: A meta-analysis of voxel-based morphometry studies

(2012) Chien-Han Lai   PSYCHIATRY RESEARCH-NEUROIMAGING

The current state of play on the molecular genetics of depression

(2012) S. Cohen-Woods et al.   PSYCHOLOGICAL MEDICINE

Escitalopram reduces circulating pro-inflammatory cytokines and improves depressive behavior without affecting sleep in a rat model of post-cardiac infarct depression

(2011) Thierno Madjou Bah et al.   BEHAVIOURAL BRAIN RESEARCH

Plasticity of gray matter volume: The cellular and synaptic plasticity that underlies volumetric change

(2011) Brenda J. Anderson   DEVELOPMENTAL PSYCHOBIOLOGY

An evidence-based approach to establish the functional and clinical significance of copy number variants in intellectual and developmental disabilities

(2011) Erin B. Kaminsky et al.   GENETICS IN MEDICINE

Voxelwise meta-analysis of gray matter reduction in major depressive disorder

(2011) Ming-Ying Du et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

SNP-based analysis of neuroactive ligand–receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response: Data from the CATIE study

(2011) Daniel E. Adkins et al.   SCHIZOPHRENIA RESEARCH

Genome-Wide Association Scan of Trait Depression

(2010) Antonio Terracciano et al.   BIOLOGICAL PSYCHIATRY

Genome-Wide Association-, Replication-, and Neuroimaging Study Implicates HOMER1 in the Etiology of Major Depression

(2010) Marcella Rietschel et al.   BIOLOGICAL PSYCHIATRY

Genetic Associations of Brain Structural Networks in Schizophrenia: A Preliminary Study

(2010) Kanchana Jagannathan et al.   BIOLOGICAL PSYCHIATRY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample

(2010) Srdjan Djurovic et al.   JOURNAL OF AFFECTIVE DISORDERS

The Prostaglandin E2 E-Prostanoid 4 Receptor Exerts Anti-Inflammatory Effects in Brain Innate Immunity

(2010) J. Shi et al.   JOURNAL OF IMMUNOLOGY

Chemerin Contributes to Inflammation by Promoting Macrophage Adhesion to VCAM-1 and Fibronectin through Clustering of VLA-4 and VLA-5

(2010) R. Hart et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association study of recurrent early-onset major depressive disorder

(2010) J Shi et al.   MOLECULAR PSYCHIATRY

Genome-wide association study of major depressive disorder: new results, meta-analysis and lessons learned

(2010) N R Wray et al.   MOLECULAR PSYCHIATRY

Investigating the Interaction between Spatial Perception and Working Memory in the Human Medial Temporal Lobe

(2009) Andy C. H. Lee et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics

(2009) J L McClay et al.   MOLECULAR PSYCHIATRY

Involvement of Medial Temporal Lobe Structures in Memory and Perception

(2009) Mark G. Baxter   NEURON

Immune Proteins in Brain Development and Synaptic Plasticity

(2009) Lisa M. Boulanger   NEURON

The Brain's Default Network

(2008) Randy L. Buckner et al.   Annals of the New York Academy of Sciences

Functional connectivity of default mode network components: Correlation, anticorrelation, and causality

(2008) Lucina Q. Uddin et al.   HUMAN BRAIN MAPPING

A Parallel Independent Component Analysis Approach to Investigate Genomic Influence on Brain Function

(2008) Jingyu Liu et al.   IEEE SIGNAL PROCESSING LETTERS

Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts

(2008) P Muglia et al.   MOLECULAR PSYCHIATRY

Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA

(2007) Jingyu Liu et al.   HUMAN BRAIN MAPPING