Dissociation mechanism of GDP from Cdc42 via DOCK9 revealed by molecular dynamics simulations

Regulating Cdc42 and Its Signaling Pathways in Cancer: Small Molecules and MicroRNA as New Treatment Candidates

(2018) Xing-Hua Xiao et al.   MOLECULES

Rho GTPase signaling complexes in cell migration and invasion

(2017) Campbell D. Lawson et al.   JOURNAL OF CELL BIOLOGY

A disappearing act performed by magnesium: the nucleotide exchange mechanism of Ran GTPase by quantum mechanics/molecular mechanics studies

(2016) Maura C. Mooney et al.   THEORETICAL CHEMISTRY ACCOUNTS

Structural Mechanisms and Drug Discovery Prospects of Rho GTPases

(2016) Cameron Smithers et al.   Cells

Cdc42: Role in Cancer Management

(2015) Muhammad Imran Qadir et al.   Chemical Biology & Drug Design

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB

(2015) James A. Maier et al.   Journal of Chemical Theory and Computation

Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos

(2015) Thomas Jank et al.   Nature Communications

Dock-family exchange factors in cell migration and disease

(2014) Gilles Gadea et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Insights into the biological functions of Dock family guanine nucleotide exchange factors

(2014) M. Laurin et al.   GENES & DEVELOPMENT

Dock GEFs and their therapeutic potential: Neuroprotection and axon regeneration

(2014) Kazuhiko Namekata et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Taking into Account the Ion-Induced Dipole Interaction in the Nonbonded Model of Ions

(2013) Pengfei Li et al.   Journal of Chemical Theory and Computation

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

(2013) D R Cook et al.   ONCOGENE

MMPBSA.py: An Efficient Program for End-State Free Energy Calculations

(2012) Bill R. Miller et al.   Journal of Chemical Theory and Computation

Cdc42 in oncogenic transformation, invasion, and tumorigenesis

(2011) Kristy Stengel et al.   CELLULAR SIGNALLING

The VEGF/Rho GTPase signalling pathway: A promising target for anti-angiogenic/anti-invasion therapy

(2011) Roy van der Meel et al.   DRUG DISCOVERY TODAY

CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients

(2010) Leilei Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Faciogenital Dysplasia Protein Fgd1 Regulates Invadopodia Biogenesis and Extracellular Matrix Degradation and Is Up-regulated in Prostate and Breast Cancer

(2009) I. Ayala et al.   CANCER RESEARCH

The role of Dock family Rho-GEFs in dendrite morphogenesis

(2009) Hironori Katoh et al.   NEUROSCIENCE RESEARCH

Activation of Rho GTPases by DOCK Exchange Factors Is Mediated by a Nucleotide Sensor

(2009) J. Yang et al.   SCIENCE

DOCK10-Mediated Cdc42 Activation Is Necessary for Amoeboid Invasion of Melanoma Cells

(2008) Gilles Gadea et al.   CURRENT BIOLOGY

Insights into the interactions between HIV-1 integrase and human LEDGF/p75 by molecular dynamics simulation and free energy calculation

(2008) Yaxue Zhao et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS