UropathogenicEscherichia coliemploys both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

New Insights into the Role of Zinc Acquisition and Zinc Tolerance in Group A Streptococcal Infection

(2018) Cheryl-lynn Y. Ong et al.   INFECTION AND IMMUNITY

For when bacterial infections persist: Toll-like receptor-inducible direct antimicrobial pathways in macrophages

(2018) Claudia J. Stocks et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages

(2018) Ambika M. V. Murthy et al.   Virulence

Investigation of the Role of Genes Encoding Zinc Exporters zntA, zitB, and fieF during Salmonella Typhimurium Infection

(2018) Kaisong Huang et al.   Frontiers in Microbiology

Nitric Oxide Disrupts Zinc Homeostasis in Salmonella enterica Serovar Typhimurium

(2018) Elaine R. Frawley et al.   mBio

Localization of all four ZnT zinc transporters in Dictyostelium and impact of ZntA and ZntB knockout on bacteria killing

(2018) Caroline Barisch et al.   JOURNAL OF CELL SCIENCE

Non-canonical activation of OmpR drives acid and osmotic stress responses in single bacterial cells

(2017) Smarajit Chakraborty et al.   Nature Communications

Identification of IncA/C Plasmid Replication and Maintenance Genes and Development of a Plasmid Multi-Locus Sequence-Typing Scheme

(2016) Steven J. Hancock et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages

(2016) Ronan Kapetanovic et al.   FASEB JOURNAL

Copper Is a Host Effector Mobilized to Urine during Urinary Tract Infection To Impair Bacterial Colonization

(2016) Amanda N. Hyre et al.   INFECTION AND IMMUNITY

IL-4 Induces Metallothionein 3- and SLC30A4-Dependent Increase in Intracellular Zn 2+ that Promotes Pathogen Persistence in Macrophages

(2016) Kavitha Subramanian Vignesh et al.   Cell Reports

UropathogenicEscherichia coliEngages CD14-Dependent Signaling to Enable Bladder-Macrophage-Dependent Control of Acute Urinary Tract Infection

(2015) Alison J. Carey et al.   JOURNAL OF INFECTIOUS DISEASES

Analyzing free zinc(ii) ion concentrations in cell biology with fluorescent chelating molecules

(2015) Wolfgang Maret   Metallomics

Back to the metal age: battle for metals at the host–pathogen interface during urinary tract infection

(2015) Sargurunathan Subashchandrabose et al.   Metallomics

Strain- and host species-specific inflammasome activation, IL-1β release and cell death in macrophages infected with uropathogenic Escherichia coli

(2015) K Schaale et al.   Mucosal Immunology

Zinc disrupts central carbon metabolism and capsule biosynthesis in Streptococcus pyogenes

(2015) Cheryl-lynn Y. Ong et al.   Scientific Reports

Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium

(2014) Marzena Schiwon et al.   CELL

An Antimicrobial Role for Zinc in Innate Immune Defense Against Group A Streptococcus

(2014) Cheryl-lynn Y. Ong et al.   JOURNAL OF INFECTIOUS DISEASES

Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Management in Streptococcus pneumoniae

(2014) Bart A. Eijkelkamp et al.   PLoS One

Global dissemination of a multidrug resistant Escherichia coli clone

(2014) N. K. Petty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host-specific induction ofEscherichia colifitness genes during human urinary tract infection

(2014) Sargurunathan Subashchandrabose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo mRNA Profiling of Uropathogenic Escherichia coli from Diverse Phylogroups Reveals Common and Group-Specific Gene Expression Profiles

(2014) P. Bielecki et al.   mBio

Cupric Yersiniabactin Is a Virulence-Associated Superoxide Dismutase Mimic

(2013) Kaveri S. Chaturvedi et al.   ACS Chemical Biology

The Biology of the PmrA/PmrB Two-Component System: The Major Regulator of Lipopolysaccharide Modifications

(2013) H. Deborah Chen et al.   Annual Review of Microbiology

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

(2013) Sian L. Stafford et al.   BIOSCIENCE REPORTS

Expression of the antimicrobial peptide cathelicidin in myeloid cells is required for lung tumor growth

(2013) D Li et al.   ONCOGENE

The Serum Resistome of a Globally Disseminated Multidrug Resistant Uropathogenic Escherichia coli Clone

(2013) Minh-Duy Phan et al.   PLoS Genetics

Iron, copper, zinc, and manganese transport and regulation in pathogenic Enterobacteria: correlations between strains, site of infection and the relative importance of the different metal transport systems for virulence

(2013) Gaëlle Porcheron et al.   Frontiers in Cellular and Infection Microbiology

Clonal Composition and Community Clustering of Drug-Susceptible and -Resistant Escherichia coli Isolates from Bloodstream Infections

(2012) Sheila Adams-Sapper et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Silver(I), Mercury(II), Cadmium(II), and Zinc(II) Target Exposed Enzymic Iron-Sulfur Clusters when They Toxify Escherichia coli

(2012) Fang Fang Xu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Copper redistribution in murine macrophages in response toSalmonellainfection

(2012) Maud E. S. Achard et al.   BIOCHEMICAL JOURNAL

Escherichia coli UropathogenesisIn Vitro: Invasion, Cellular Escape, and Secondary Infection Analyzed in a Human Bladder Cell Infection Model

(2012) Thomas E. Andersen et al.   INFECTION AND IMMUNITY

ZntR-mediated transcription of zntA responds to nanomolar intracellular free zinc

(2012) Da Wang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mycobacterial P1-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages

(2011) Hélène Botella et al.   Cell Host & Microbe

Immune Dysfunction and Infections in Patients With Cirrhosis

(2011) Alexander R. Bonnel et al.   Clinical Gastroenterology and Hepatology

Intramacrophage survival of uropathogenic Escherichia coli: Differences between diverse clinical isolates and between mouse and human macrophages

(2011) Nilesh J. Bokil et al.   IMMUNOBIOLOGY

Attenuation of human neutrophil migration and function by uropathogenic bacteria

(2011) Jennifer A. Loughman et al.   MICROBES AND INFECTION

Insights into a Multidrug Resistant Escherichia coli Pathogen of the Globally Disseminated ST131 Lineage: Genome Analysis and Virulence Mechanisms

(2011) Makrina Totsika et al.   PLoS One

A Molecular Mechanism for Bacterial Susceptibility to Zinc

(2011) Christopher A. McDevitt et al.   PLoS Pathogens

Intracellular Lifestyles and Immune Evasion Strategies of UropathogenicEscherichia coli

(2010) David A. Hunstad et al.   Annual Review of Microbiology

Cirrhotic Patients Are at Risk for Health Care–Associated Bacterial Infections

(2010) Manuela Merli et al.   Clinical Gastroenterology and Hepatology

The Multi-Copper-Ion Oxidase CueO of Salmonella enterica Serovar Typhimurium Is Required for Systemic Virulence

(2010) M. E. S. Achard et al.   INFECTION AND IMMUNITY

Genetic Diversity and Virulence Profiles of Escherichia coli Isolates Causing Spontaneous Bacterial Peritonitis and Bacteremia in Patients with Cirrhosis

(2010) F. Bert et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Dissemination and Systemic Colonization of Uropathogenic Escherichia coli in a Murine Model of Bacteremia

(2010) S. N. Smith et al.   mBio

Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis*

(2009) Daren L. Knoell et al.   CRITICAL CARE MEDICINE

A Role for the ATP7A Copper-transporting ATPase in Macrophage Bactericidal Activity

(2009) Carine White et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity

(2009) L. Macomber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of the Extraintestinal Pathogenic Escherichia coli ZnuACB and ZupT Zinc Transporters during Urinary Tract Infection

(2008) M. Sabri et al.   INFECTION AND IMMUNITY