Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

Zinc Signals Are Essential for Lipopolysaccharide-Induced Signal Transduction in Monocytes

(2014) H. Haase et al.   JOURNAL OF IMMUNOLOGY

Antimicrobial activity of metals: mechanisms, molecular targets and applications

(2013) Joseph A. Lemire et al.   NATURE REVIEWS MICROBIOLOGY

High Dose Zinc Supplementation Induces Hippocampal Zinc Deficiency and Memory Impairment with Inhibition of BDNF Signaling

(2013) Yang Yang et al.   PLoS One

ZIP8 Regulates Host Defense through Zinc-Mediated Inhibition of NF-κB

(2013) Ming-Jie Liu et al.   Cell Reports

Silver(I), Mercury(II), Cadmium(II), and Zinc(II) Target Exposed Enzymic Iron-Sulfur Clusters when They Toxify Escherichia coli

(2012) Fang Fang Xu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Copper redistribution in murine macrophages in response toSalmonellainfection

(2012) Maud E. S. Achard et al.   BIOCHEMICAL JOURNAL

Copper in Microbial Pathogenesis: Meddling with the Metal

(2012) Marie I. Samanovic et al.   Cell Host & Microbe

Zip14 expression induced by lipopolysaccharides in macrophages attenuates inflammatory response

(2012) Ahmed Sayadi et al.   INFLAMMATION RESEARCH

Streptococcus pneumoniae Uses Glutathione To Defend against Oxidative Stress and Metal Ion Toxicity

(2012) A. J. Potter et al.   JOURNAL OF BACTERIOLOGY

Copper Homeostasis at the Host-Pathogen Interface: FIGURE 1.

(2012) Victoria Hodgkinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of human zinc deficiency: 50 years later

(2012) Ananda S. Prasad   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Nutritional immunity: transition metals at the pathogen–host interface

(2012) M. Indriati Hood et al.   NATURE REVIEWS MICROBIOLOGY

Prophylactic zinc supplementation reduces bacterial load and improves survival in a murine model of sepsis

(2012) Jeffrey E. Nowak et al.   Pediatric Critical Care Medicine

Zinc Transporter ZIP14 Functions in Hepatic Zinc, Iron and Glucose Homeostasis during the Innate Immune Response (Endotoxemia)

(2012) Tolunay Beker Aydemir et al.   PLoS One

Evidence for additive and interaction effects of host genotype and infection in malaria

(2012) Y. Idaghdour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis

(2012) Ahmed Achouiti et al.   PLoS Pathogens

A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission

(2011) Beth Y Besecker et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Mycobacterial P1-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages

(2011) Hélène Botella et al.   Cell Host & Microbe

The disposition and intestinal absorption of zinc in rats

(2011) Tohru Yasuno et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The Efficacy of Zinc Supplementation on Outcome of Children with Severe Pneumonia. A Randomized Double-blind Placebo-controlled Clinical Trial

(2011) Ehsan Valavi et al.   INDIAN JOURNAL OF PEDIATRICS

Regulation of T cell receptor signaling by activation-induced zinc influx

(2011) Mingcan Yu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Genomic analysis, cytokine expression, and microRNA profiling reveal biomarkers of human dietary zinc depletion and homeostasis

(2011) M.-S. Ryu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Molecular Mechanism for Bacterial Susceptibility to Zinc

(2011) Christopher A. McDevitt et al.   PLoS Pathogens

Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-κB

(2010) Shengying Bao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

TheDrosophilaCopper Transporter Ctr1C Functions in Male Fertility

(2010) Dominik Steiger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Copper Homeostasis inSalmonellaIs Atypical and Copper-CueP Is a Major Periplasmic Metal Complex

(2010) Deenah Osman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH Oxidase-Dependent Reactive Oxygen Species Mediate Amplified TLR4 Signaling and Sepsis-Induced Mortality in Nrf2-Deficient Mice

(2010) X. Kong et al.   JOURNAL OF IMMUNOLOGY

Metallomic Analysis of Macrophages Infected withHistoplasma capsulatumReveals a Fundamental Role for Zinc in Host Defenses

(2010) Michael S. Winters et al.   JOURNAL OF INFECTIOUS DISEASES

Oral Zinc for the Treatment of Acute Gastroenteritis in Polish Children: A Randomized, Double-Blind, Placebo-Controlled Trial

(2010) Bernadeta Patro et al.   JOURNAL OF PEDIATRICS

Zinc-suppressed inflammatory cytokines by induction of A20-mediated inhibition of nuclear factor-κB

(2010) Ananda S. Prasad et al.   NUTRITION

Randomized controlled trial of zinc and vitamin A as co-adjuvants for the treatment of pulmonary tuberculosis

(2010) Lovett Lawson et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Functional Significance of Zinc-Related Signaling Pathways in Immune Cells

(2009) Hajo Haase et al.   Annual Review of Nutrition

Mammalian Zinc Transporters: Nutritional and Physiologic Regulation

(2009) Louis A. Lichten et al.   Annual Review of Nutrition

Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis*

(2009) Daren L. Knoell et al.   CRITICAL CARE MEDICINE

Zinc: role in immunity, oxidative stress and chronic inflammation

(2009) Ananda S Prasad   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Pannexin-1-dependent caspase-1 activation and secretion of IL-1β is regulated by zinc

(2009) David Brough et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase

(2009) Nicholas A. Veldhuis et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Differential Processing of α- and β-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7)

(2009) Carole L. Wilson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Role for the ATP7A Copper-transporting ATPase in Macrophage Bactericidal Activity

(2009) Carine White et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-γ expression in activated human T cells

(2009) Tolunay B. Aydemir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Diarrhoea: why children are still dying and what can be done

(2009) Tessa Wardlaw et al.   LANCET

Cellular multitasking: The dual role of human Cu-ATPases in cofactor delivery and intracellular copper balance

(2008) Svetlana Lutsenko et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells

(2008) Jesse Bertinato et al.   BIOCHEMICAL JOURNAL

Copper proteins and ferroxidases in human plasma and that of wild-type and ceruloplasmin knockout mice

(2008) Lawrence W. Gray et al.   BIOCHEMICAL JOURNAL

Hematological manifestations of copper deficiency: a retrospective review

(2008) Thorvardur R. Halfdanarson et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

DFT-based molecular modeling and vibrational study of the La(III) complex of 3,3′-(benzylidene)bis(4-hydroxycoumarin)

(2008) Tzvetan Mihaylov et al.   JOURNAL OF MOLECULAR MODELING

A Meta-analysis of the Effects of Oral Zinc in the Treatment of Acute and Persistent Diarrhea

(2008) M. Lukacik et al.   PEDIATRICS

Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

(2008) Brian D. Corbin et al.   SCIENCE

Zinc supplementation increases resistance to experimental infection by Trypanosoma cruzi

(2008) Vânia Brazão et al.   VETERINARY PARASITOLOGY

Synchronizing Ca2+ and cAMP oscillations in pancreatic β-cells: a role for glucose metabolism and GLP-1 receptors?Focus on “Regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic β-cell: a computational approach”

(2007) George G. Holz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY