Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1

Checkpoint inhibitors in triple-negative breast cancer (TNBC): Where to go from here

(2018) Maryann J. Kwa et al.   CANCER

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

(2018) Elham Azizi et al.   CELL

Regulation of Programmed Death Ligand 1 (PD-L1) Expression in Breast Cancer Cell Lines In Vitro and in Immunodeficient and Humanized Tumor Mice

(2018) Eva-Maria Rom-Jurek et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chemotherapy induces enrichment of CD47+/CD73+/PDL1+immune evasive triple-negative breast cancer cells

(2018) Debangshu Samanta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-κB/SOX4 signaling

(2018) Neng Wang et al.   Cell Death & Disease

Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer

(2018) Peter Schmid et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti–PD-L1)

(2018) Marcin Kowanetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

COX2/mPGES1/PGE2pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells

(2017) Victor Prima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

(2017) Woosung Chung et al.   Nature Communications

Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition

(2017) Carlos R. Gil Del Alcazar et al.   Cancer Discovery

Macrophages promote the progression of premalignant mammary lesions to invasive cancer

(2017) Emily C. Carron et al.   Oncotarget

Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents

(2017) Oakley C. Olson et al.   Cell Reports

Functional Expression of Programmed Death-Ligand 1 (B7-H1) by Immune Cells and Tumor Cells

(2017) Rachel M. Gibbons Johnson et al.   Frontiers in Immunology

nab-Paclitaxel as a potential partner with checkpoint inhibitors in solid tumors

(2016) Hatem Soliman   OncoTargets and Therapy

Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells

(2016) A. Spiegel et al.   Cancer Discovery

IL-1 drives breast cancer growth and bone metastasis in vivo

(2016) Ingunn Holen et al.   Oncotarget

Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2015) E. Senkus et al.   ANNALS OF ONCOLOGY

Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor- B to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer

(2015) J. Peng et al.   CANCER RESEARCH

Classifying Cancers Based on T-cell Infiltration and PD-L1

(2015) Michele W.L. Teng et al.   CANCER RESEARCH

Clinical relevance of host immunity in breast cancer: from TILs to the clinic

(2015) Peter Savas et al.   Nature Reviews Clinical Oncology

Combination cancer immunotherapies tailored to the tumour microenvironment

(2015) Mark J. Smyth et al.   Nature Reviews Clinical Oncology

The Interplay of Immunotherapy and Chemotherapy: Harnessing Potential Synergies

(2015) Leisha A. Emens et al.   Cancer Immunology Research

Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

(2014) Brian Ruffell et al.   CANCER CELL

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

IL-10 enhances the phenotype of M2 macrophages induced by IL-4 and confers the ability to increase eosinophil migration

(2014) Naoyuki Makita et al.   INTERNATIONAL IMMUNOLOGY

Depletion of the Aryl Hydrocarbon Receptor in MDA-MB-231 Human Breast Cancer Cells Altered the Expression of Genes in Key Regulatory Pathways of Cancer

(2014) Gennifer Goode et al.   PLoS One

Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway

(2014) C. Gorrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Macrophages Different from M1/M2 Macrophages Inhibit T Cell Mitogenesis while Upregulating Th17 Polarization

(2014) Yutaka Tatano et al.   Scientific Reports

An aryl hydrocarbon receptor induces VEGF expression through ATF4 under glucose deprivation in HepG2

(2013) Jun Terashima et al.   BMC MOLECULAR BIOLOGY

CX3CL1 Promotes Breast Cancer via Transactivation of the EGF Pathway

(2013) M. Tardaguila et al.   CANCER RESEARCH

Cross-talk between Aryl Hydrocarbon Receptor and the Inflammatory Response

(2013) Christoph F. A. Vogel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deciphering Signatures of Mutational Processes Operative in Human Cancer

(2013) Ludmil B. Alexandrov et al.   Cell Reports

Sequence analysis of mutations and translocations across breast cancer subtypes

(2012) Shantanu Banerji et al.   NATURE

The Specificity of Innate Immune Responses Is Enforced by Repression of Interferon Response Elements by NF- B p50

(2011) C. S. Cheng et al.   Science Signaling

Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

(2011) David G. DeNardo et al.   Cancer Discovery

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Bcl-6 and NF- B cistromes mediate opposing regulation of the innate immune response

(2010) G. D. Barish et al.   GENES & DEVELOPMENT

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

(2010) Serena Ghisletti et al.   IMMUNITY

CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages

(2009) David G. DeNardo et al.   CANCER CELL

Molecular mechanism and function of CD40/CD40L engagement in the immune system

(2009) Raul Elgueta et al.   IMMUNOLOGICAL REVIEWS

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

Nuclear Ubiquitin Ligases, NF- B Degradation, and the Control of Inflammation

(2008) G. Natoli et al.   Science Signaling