Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 12, Pages 4472-4477
Publisher
Proceedings of the National Academy of Sciences
Online
2014-02-25
DOI
10.1073/pnas.1324136111
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Contralateral mastectomy improves survival in women with BRCA1/2-associated breast cancer
- (2013) D. Gareth R. Evans et al. BREAST CANCER RESEARCH AND TREATMENT
- 17β-Estradiol Activates Glucose Uptake via GLUT4 Translocation and PI3K/Akt Signaling Pathway in MCF-7 Cells
- (2013) Pablo Garrido et al. ENDOCRINOLOGY
- Overcoming endocrine resistance in breast cancer: role of the PI3K and the mTOR pathways
- (2013) Aaron Provenzano et al. Expert Review of Anticancer Therapy
- BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival
- (2013) Chiara Gorrini et al. JOURNAL OF EXPERIMENTAL MEDICINE
- ROS-mediated activation of AKT induces apoptosis via pVHL in prostate cancer cells
- (2013) Mahandranauth A. Chetram et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Phosphoinositide 3-Kinase p110δ Mediates Estrogen- and FSH-Stimulated Ovarian Follicle Growth
- (2013) Qian Li et al. MOLECULAR ENDOCRINOLOGY
- Modulation of oxidative stress as an anticancer strategy
- (2013) Chiara Gorrini et al. NATURE REVIEWS DRUG DISCOVERY
- DJ-1-Dependent Regulation of Oxidative Stress in the Retinal Pigment Epithelium (RPE)
- (2013) Karen G. Shadrach et al. PLoS One
- Parkinson-susceptibility gene DJ-1/PARK7 protects the murine heart from oxidative damage in vivo
- (2013) F. Billia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress
- (2013) C. Bassi et al. SCIENCE
- Estrogen receptor signaling as a target for novel breast cancer therapeutics
- (2012) Jack-Michel Renoir et al. BIOCHEMICAL PHARMACOLOGY
- Ligand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells
- (2012) Anne-Marie Gaben et al. BMC CANCER
- Molecular insights on basal-like breast cancer
- (2012) Mev Dominguez Valentin et al. BREAST CANCER RESEARCH AND TREATMENT
- Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
- (2012) Yoichiro Mitsuishi et al. CANCER CELL
- ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons
- (2012) Alvin P. Joselin et al. HUMAN MOLECULAR GENETICS
- Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition
- (2012) Kevin Bray et al. PLoS One
- PI3K Inhibition Impairs BRCA1/2 Expression and Sensitizes BRCA-Proficient Triple-Negative Breast Cancer to PARP Inhibition
- (2012) Yasir H. Ibrahim et al. Cancer Discovery
- Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer
- (2012) Ashish Juvekar et al. Cancer Discovery
- Abrogating endocrine resistance by targeting ERα and PI3K in breast cancer
- (2012) Emily M. Fox et al. Frontiers in Oncology
- Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer
- (2011) Todd W. Miller et al. JOURNAL OF CLINICAL ONCOLOGY
- Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor
- (2011) S.-M. Maira et al. MOLECULAR CANCER THERAPEUTICS
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers
- (2010) Susan M. Domchek et al. BREAST CANCER RESEARCH AND TREATMENT
- Global Downstream Pathway Analysis Reveals a Dependence of Oncogenic NF-E2-Related Factor 2 Mutation on the mTOR Growth Signaling Pathway
- (2010) T. Shibata et al. CANCER RESEARCH
- Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
- (2010) I. Irrcher et al. HUMAN MOLECULAR GENETICS
- Progesterone induces adult mammary stem cell expansion
- (2010) Purna A. Joshi et al. NATURE
- Alkylation of the Tumor Suppressor PTEN Activates Akt and β-Catenin Signaling: A Mechanism Linking Inflammation and Oxidative Stress with Cancer
- (2010) Tracy M. Covey et al. PLoS One
- Breast cancer risks in individuals testing negative for a known family mutation in BRCA1 or BRCA2
- (2009) S. M. Domchek et al. BREAST CANCER RESEARCH AND TREATMENT
- Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
- (2009) Zachary T. Schafer et al. NATURE
- BRCA1—sowing the seeds crooked in the furrow
- (2007) William D Foulkes NATURE GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started