Par3 is essential for the establishment of planar cell polarity of inner ear hair cells

The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain

(2017) Zhen Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles

(2017) Kimberly Siletti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells

(2017) Tao Jiang et al.   eLife

The GPSM2/LGN GoLoco motifs are essential for hearing

(2015) Yoni Bhonker et al.   MAMMALIAN GENOME

Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling

(2015) Sung-Ho Huh et al.   eLife

Developmental regulation of planar cell polarity and hair-bundle morphogenesis in auditory hair cells: lessons from human and mouse genetics

(2015) Xiaowei Lu et al.   Wiley Interdisciplinary Reviews-Developmental Biology

The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea

(2015) A. Kirjavainen et al.   Biology Open

Par3–mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN

(2014) Scott E. Williams et al.   NATURE CELL BIOLOGY

Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities

(2013) T. Fukuda et al.   DEVELOPMENT

Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization

(2013) C. W. Sipe et al.   DEVELOPMENT

Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion

(2013) R. Moore et al.   DEVELOPMENT

A Molecular Blueprint at the Apical Surface Establishes Planar Asymmetry in Cochlear Hair Cells

(2013) Basile Tarchini et al.   DEVELOPMENTAL CELL

Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton

(2013) Jerome Ezan et al.   NATURE CELL BIOLOGY

A balance of form and function: Planar polarity and development of the vestibular maculae

(2013) Michael R. Deans   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of Microtubule Stability and Organization by Mammalian Par3 in Specifying Neuronal Polarity

(2012) She Chen et al.   DEVELOPMENTAL CELL

The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility

(2012) Maki Ishida-Takagishi et al.   Nature Communications

Differentiation of the Lateral Compartment of the Cochlea Requires a Temporally Restricted FGF20 Signal

(2012) Sung-Ho Huh et al.   PLOS BIOLOGY

Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice

(2011) Katrin Arnold et al.   Cell Stem Cell

Principles of planar polarity in animal development

(2011) L. V. Goodrich et al.   DEVELOPMENT

Kif3a regulates planar polarization of auditory hair cells through both ciliary and non-ciliary mechanisms

(2011) Conor W. Sipe et al.   DEVELOPMENT

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

Nectins Establish a Checkerboard-Like Cellular Pattern in the Auditory Epithelium

(2011) H. Togashi et al.   SCIENCE

Emx2 and early hair cell development in the mouse inner ear

(2010) Matthew Holley et al.   DEVELOPMENTAL BIOLOGY

The cell biology of hearing

(2010) Martin Schwander et al.   JOURNAL OF CELL BIOLOGY

PI3 Kinase Signals BCR-Dependent Mature B Cell Survival

(2009) Lakshmi Srinivasan et al.   CELL

Par3 and Dynein Associate to Regulate Local Microtubule Dynamics and Centrosome Orientation during Migration

(2009) Jan Schmoranzer et al.   CURRENT BIOLOGY

The Small GTPase Rac1 Regulates Auditory Hair Cell Morphogenesis

(2009) C. M. Grimsley-Myers et al.   JOURNAL OF NEUROSCIENCE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Rho-Kinase Phosphorylates PAR-3 and Disrupts PAR Complex Formation

(2008) Masanori Nakayama et al.   DEVELOPMENTAL CELL