Par3–mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN

Oriented divisions, fate decisions

(2013) Scott E Williams et al.   CURRENT OPINION IN CELL BIOLOGY

aPKCλ controls epidermal homeostasis and stem cell fate through regulation of division orientation

(2013) Michaela T. Niessen et al.   JOURNAL OF CELL BIOLOGY

An Autoinhibited Conformation of LGN Reveals a Distinct Interaction Mode between GoLoco Motifs and TPR Motifs

(2013) Zhu Pan et al.   STRUCTURE

Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis

(2013) Daichi Kawaguchi et al.   Nature Communications

Tumor Type-Dependent Function of the Par3 Polarity Protein in Skin Tumorigenesis

(2012) Sandra Iden et al.   CANCER CELL

The Par Complex and Integrins Direct Asymmetric Cell Division in Adult Intestinal Stem Cells

(2012) Spyros Goulas et al.   Cell Stem Cell

Spindle orientation in mammalian cerebral cortical development

(2012) Madeline A Lancaster et al.   CURRENT OPINION IN NEUROBIOLOGY

Drosophila neuroblasts: a model for stem cell biology

(2012) C. C. F. Homem et al.   DEVELOPMENT

Control of asymmetric cell division of mammalian neural progenitors

(2012) Atsunori Shitamukai et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration

(2012) Panteleimon Rompolas et al.   NATURE

Inscuteable Regulates the Pins-Mud Spindle Orientation Pathway

(2012) Jonathon F. Mauser et al.   PLoS One

Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium

(2011) Ahmed HK El-Hashash et al.   DEVELOPMENT

Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development

(2011) Xavier Morin et al.   DEVELOPMENTAL CELL

Cell polarity and spindle orientation in the distal epithelium of embryonic lung

(2011) Ahmed H. El-Hashash et al.   DEVELOPMENTAL DYNAMICS

A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells

(2011) Elise Peyre et al.   JOURNAL OF CELL BIOLOGY

LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways

(2011) Jinwei Zhu et al.   MOLECULAR CELL

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

(2011) Scott E. Williams et al.   NATURE

Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation

(2011) Chen Luxenburg et al.   NATURE CELL BIOLOGY

Mouse Inscuteable Induces Apical-Basal Spindle Orientation to Facilitate Intermediate Progenitor Generation in the Developing Neocortex

(2011) Maria Pia Postiglione et al.   NEURON

Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions

(2011) S. Culurgioni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)

(2011) S. Yuzawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Par3 Controls Epithelial Spindle Orientation by aPKC-Mediated Phosphorylation of Apical Pins

(2010) Yi Hao et al.   CURRENT BIOLOGY

The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex

(2010) Andrew B. Gladden et al.   DEVELOPMENTAL CELL

Robust control of mitotic spindle orientation in the developing epidermis

(2010) Nicholas D. Poulson et al.   JOURNAL OF CELL BIOLOGY

Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos

(2010) Slobodan Beronja et al.   NATURE MEDICINE

Asymmetric cell division: recent developments and their implications for tumour biology

(2010) Juergen A. Knoblich   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division

(2009) F. Coumailleau et al.   NATURE

Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi

(2009) Jennifer L. Mummery-Widmer et al.   NATURE

Spindle orientation during asymmetric cell division

(2009) Karsten H. Siller et al.   NATURE CELL BIOLOGY

Mammalian Par3 Regulates Progenitor Cell Asymmetric Division via Notch Signaling in the Developing Neocortex

(2009) Ronald S. Bultje et al.   NEURON

Polarization of Drosophila Neuroblasts During Asymmetric Division

(2009) K. E. Prehoda   Cold Spring Harbor Perspectives in Biology

Mechanisms of Asymmetric Stem Cell Division

(2008) Juergen A. Knoblich   CELL

Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity

(2008) Shadmehr Demehri et al.   PLOS BIOLOGY